Open Access

Ectopic gastric mucosa in the submucosa of the stomach: A case report

  • Authors:
    • Jian-Hua Xi
    • Nai-Ying Sun
    • Wen-Jun Guo
    • Xing-Jie Yang
  • View Affiliations

  • Published online on: October 2, 2023     https://doi.org/10.3892/etm.2023.12238
  • Article Number: 539
  • Copyright: © Xi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Under normal circumstances, gastric mucosa only exists within the stomach. However, in certain situations, gastric mucosal tissue may undergo ectopia, commonly occurring in the esophagus and intestine, with rare occurrences within the stomach itself. A comprehensive literature review was performed to understand the distinct characteristics of ectopic gastric mucosa (EGM) in the stomach and investigate a rare incident of this disease, providing an in‑depth analysis of the clinical, histopathologic, and differential diagnostic findings. The case was a 47‑year‑old man with acid reflux, heartburn, abdominal distension, and diarrhea (5‑10 times daily) for >10 years. A gastroscope indicated a submucosal protuberance lesion in the gastric body that felt hard with biopsy forceps. A well‑defined nodule under the mucosal muscle was revealed microscopically, composed of epithelial elements and no atypia. Immunohistochemical staining demonstrated similar EGM expression patterns compared with normal gastric mucosa. The present case report highlights the importance of accurate EGM diagnosis and understanding.
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November-2023
Volume 26 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Xi J, Sun N, Guo W and Yang X: Ectopic gastric mucosa in the submucosa of the stomach: A case report. Exp Ther Med 26: 539, 2023
APA
Xi, J., Sun, N., Guo, W., & Yang, X. (2023). Ectopic gastric mucosa in the submucosa of the stomach: A case report. Experimental and Therapeutic Medicine, 26, 539. https://doi.org/10.3892/etm.2023.12238
MLA
Xi, J., Sun, N., Guo, W., Yang, X."Ectopic gastric mucosa in the submucosa of the stomach: A case report". Experimental and Therapeutic Medicine 26.5 (2023): 539.
Chicago
Xi, J., Sun, N., Guo, W., Yang, X."Ectopic gastric mucosa in the submucosa of the stomach: A case report". Experimental and Therapeutic Medicine 26, no. 5 (2023): 539. https://doi.org/10.3892/etm.2023.12238