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Case Report

Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report

  • Authors:
    • Nan Liu
    • Yuefeng Jiang
    • Jiang Du
    • Chuifeng Fan
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    Affiliations: Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences of China Medical University, Heping, Shenyang 110001, P.R. China
  • Article Number: 261
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    Published online on: April 23, 2024
       https://doi.org/10.3892/etm.2024.12549
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Abstract

Ossifying fibromyxoid tumor (OFMT) of the soft parts is a mesenchymal neoplasm of uncertain lineage. Fibromyxoid matrix and peripheral metaplastic bone are common histological features of this type of tumor. In the present study, a case of OFMT in a 33‑year‑old female was reported. The patient was referred to the First Affiliated Hospital of China Medical University (Shenyan, China) in January 2018. The patient had developed a mass in the left upper arm 6 months prior to presentation, which was slowly enlarging. The tumor was 1.5 cm in diameter, with hard texture. Histologically, the tumor showed a clear boundary with no invasion into the adjacent tissue. The majority of tumor cells were round and medium‑sized, with abundant pale cytoplasm, without obvious atypia and densely arranged in sheets. The tumor tissue was characterized by cartilage‑like morphology and fibromyxoid and hyalinization matrix. Mitotic index was <1/10 high‑power fields. Additionally, tumor cells were positive for S‑100 and vimentin expression, but negative for smooth muscle actin, CD34, cytokeratin, desmin, human melanoma black 45 and melanoma A. Ki67 index was ~1%. The patient underwent surgery and the tumor was totally removed. No recurrence was observed at the final 6‑year follow‑up. Based on the aforementioned findings, the patient was diagnosed as typical OFMT. Slow growth and clear boundaries often suggest an indolent nature to this type of tumor. However, close follow‑up should be performed due to its malignant potential. 
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Copy and paste a formatted citation
Spandidos Publications style
Liu N, Jiang Y, Du J and Fan C: Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report. Exp Ther Med 27: 261, 2024.
APA
Liu, N., Jiang, Y., Du, J., & Fan, C. (2024). Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report. Experimental and Therapeutic Medicine, 27, 261. https://doi.org/10.3892/etm.2024.12549
MLA
Liu, N., Jiang, Y., Du, J., Fan, C."Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report". Experimental and Therapeutic Medicine 27.6 (2024): 261.
Chicago
Liu, N., Jiang, Y., Du, J., Fan, C."Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report". Experimental and Therapeutic Medicine 27, no. 6 (2024): 261. https://doi.org/10.3892/etm.2024.12549
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Spandidos Publications style
Liu N, Jiang Y, Du J and Fan C: Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report. Exp Ther Med 27: 261, 2024.
APA
Liu, N., Jiang, Y., Du, J., & Fan, C. (2024). Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report. Experimental and Therapeutic Medicine, 27, 261. https://doi.org/10.3892/etm.2024.12549
MLA
Liu, N., Jiang, Y., Du, J., Fan, C."Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report". Experimental and Therapeutic Medicine 27.6 (2024): 261.
Chicago
Liu, N., Jiang, Y., Du, J., Fan, C."Ossifying fibromyxoid tumor of the soft tissue in the left upper arm and a review of the literature: A case report". Experimental and Therapeutic Medicine 27, no. 6 (2024): 261. https://doi.org/10.3892/etm.2024.12549
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