Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
August-2024 Volume 28 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2024 Volume 28 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Review Open Access

Potential clinical applications of current and future oral forms of desmopressin (Review)

  • Authors:
    • Karel Everaert
    • Tove Holm‑Larsen
    • George Bou Kheir
    • Sylvie Rottey
    • Jeffrey P. Weiss
    • Johan Vande Walle
    • Abdo E. Kabarriti
    • Lien Dossche
    • François Hervé
    • Anne-Françoise Spinoit
    • Jens Peter Nørgaard
    • Kristian Vinter Juul
  • View Affiliations / Copyright

    Affiliations: Faculty of Medicine and Health Sciences, Department of Human Structure and Repair, Ghent University Hospital, 9000 Ghent, Belgium, Department of Urology, Ghent University Hospital, 9000 Ghent, Belgium, Drug Research Unit and Department of Medical Oncology, Ghent University Hospital, 9000 Ghent, Belgium, Department of Urology, State University of New York Downstate Health Sciences University, New York City, NY 11203, USA, Department of Pediatric Nephrology, Ghent University Hospital, 9000 Ghent, Belgium, Faculty of Medicine and Health Sciences, Department of Internal Medicine and Pediatrics, Ghent University Hospital, 9000 Ghent, Belgium, Department of Pediatric & Reconstructive Urology, Ghent University Hospital, 9000 Ghent, Belgium, Research & Development, Ferring Pharmaceuticals A/S, Ferring International PharmaScience Center, 2770 Copenhagen, Denmark
    Copyright: © Everaert et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 303
    |
    Published online on: May 29, 2024
       https://doi.org/10.3892/etm.2024.12592
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Desmopressin is a synthetic analogue of vasopressin and a selective vasopressin receptor 2 agonist. It was first synthesised in 1967 and utilised for its antidiuretic properties. It is also used in bleeding disorders to enhance clotting. Other potential uses of the drug have been reported. The present review aims to provide a broad overview of the literature on potential further uses of oral forms of desmopressin. Key therapeutic areas of interest were identified based on known physiological activities/targets of desmopressin or reports of an effect of desmopressin in the literature. The feasibility of adequate dosing with oral forms of the drug was also considered. Systematic literature searches were carried out using the silvi.ai software for the identified areas, and summaries of available papers were included in tables and discussed. The results of the searches showed that desmopressin has been investigated for its efficacy in a number of areas, including bleeding control, renal colic, the central nervous system and oncology. Evidence suggests that oral desmopressin may have the potential to be of clinical benefit for renal colic and bleeding control in particular. However, further research is needed to clarify its effect in these areas, including randomised controlled studies and studies specifically of oral formulations (and doses). Further research may also yield findings for cancer, cognition and overactive bladder.
View Figures

Figure 1

View References

1 

Zaoral M, Kolc J and Šorm F: Amino acids and peptides. LXXI. Synthesis of 1-deamino-8-D-γ-aminobutyrine-vasopressin, 1-deamino-8-D-lysine-vasopressin, and 1-deamino-8-D-arginine-vasopressin. Collect Czech Chem Commun. 32:1250–1257. 1967.

2 

Robinson AG: DDAVP in the treatment of central diabetes insipidus. N Engl J Med. 294:507–511. 1976.PubMed/NCBI View Article : Google Scholar

3 

Desmopressin | Drugs | BNF content published by NICE. https://bnf.nice.org.uk/drugs/desmopressin/. Accessed March 22, 2023.

4 

Cash JD: DDAVP and factor VIII: A tale from Edinburgh. J Thromb Haemost. 1:619–621. 2003.PubMed/NCBI View Article : Google Scholar

5 

Mannucci PM, Ruggeri ZM, Pareti FI and Capitanio A: 1-Deamino-8-d-arginine vasopressin: A new pharmacological approach to the management of haemophilia and von Willebrands' diseases. Lancet. 1:869–872. 1977.PubMed/NCBI View Article : Google Scholar

6 

Mannucci PM: Use of desmopressin in the treatment of hemophilia A: Towards a golden jubilee. Haematologica. 103:379–381. 2018.PubMed/NCBI View Article : Google Scholar

7 

Robson WLM, Leung AKC and Norgaard JP: The comparative safety of oral versus intranasal desmopressin for the treatment of children with nocturnal enuresis. J Urol. 178:24–30. 2007.PubMed/NCBI View Article : Google Scholar

8 

Juul KV, Malmberg A, van der Meulen E, Walle JV and Nørgaard JP: Low-dose desmopressin combined with serum sodium monitoring can prevent clinically significant hyponatraemia in patients treated for Nocturia. BJU Int. 119:776–784. 2017.PubMed/NCBI View Article : Google Scholar

9 

De Bruyne P, De Guchtenaere A, Van Herzeele C, Raes A, Dehoorne J, Hoebeke P, Van Laecke E and Walle JV: Pharmacokinetics of desmopressin administered as tablet and oral lyophilisate formulation in children with monosymptomatic nocturnal enuresis. Eur J Pediatr. 173:223–228. 2014.PubMed/NCBI View Article : Google Scholar

10 

Dossche L, Michelet R, De Bruyne P, Van Herzeele C, Gasthuys E, Rittig S, Vermeulen A and Walle JV: Desmopressin oral lyophilisate in young children: New insights in pharmacokinetics and pharmacodynamics. Arch Dis Child. 106:597–602. 2021.PubMed/NCBI View Article : Google Scholar

11 

De Guchtenaere A, Van Herzeele C, Raes A, Dehoorne J, Hoebeke P, Van Laecke E and Walle JV: Oral lyophylizate formulation of desmopressin: Superior pharmacodynamics compared to tablet due to low food interaction. J Urol. 185:2308–2313. 2011.PubMed/NCBI View Article : Google Scholar

12 

Fjellestad-Paulsen A, Höglund P, Lundin S and Paulsen O: Pharmacokinetics of 1-deamino-8-D-arginine vasopressin after various routes of administration in healthy volunteers. Clin Endocrinol (Oxf). 38:177–182. 1993.PubMed/NCBI View Article : Google Scholar

13 

Rembratt A, Graugaard-Jensen C, Senderovitz T, Norgaard JP and Djurhuus JC: Pharmacokinetics and pharmacodynamics of desmopressin administered orally versus intravenously at daytime versus night-time in healthy men aged 55-70 years. Eur J Clin Pharmacol. 60:397–402. 2004.PubMed/NCBI View Article : Google Scholar

14 

Mohinani A, Patel S, Tan V, Kartika T, Olson S, DeLoughery TG and Shatzel J: Desmopressin as a hemostatic and blood sparing agent in bleeding disorders. Eur J Haematol. 110:470–479. 2023.PubMed/NCBI View Article : Google Scholar

15 

Mannucci PM: Desmopressin (DDAVP) in the treatment of bleeding disorders, Revised edition, 2012.

16 

Electronic Medicines Compendium: DDAVP/Desmopressin Injection-Summary of Product Characteristics (SmPC)-(emc). https://www.medicines.org.uk/emc/product/5447/smpc#gref. Last accessed July 12, 2023.

17 

Electronic medicines compendium: Octim Nasal Spray-Summary of Product Characteristics (SmPC) - (emc). https://www.medicines.org.uk/emc/product/89/smpc#gref. Last accessed 12 July, 2023.

18 

Akin M: Response to low-dose desmopressin by a subcutaneous route in children with type 1 von Willebrand disease. Hematology. 18:115–118. 2013.PubMed/NCBI View Article : Google Scholar

19 

Furqan F, Sham R and Kouides P: Efficacy and safety of half-dose desmopressin for bleeding prophylaxis in bleeding disorder patients undergoing predominantly low to moderate risk invasive procedures. Am J Hematol. 95:E285–E287. 2020.PubMed/NCBI View Article : Google Scholar

20 

Preijers T, Schütte LM, Kruip MJHA, Cnossen MH, Leebeek FWG, van Hest RM and Mathôt RAA: Strategies for individualized dosing of clotting factor concentrates and desmopressin in hemophilia A and B. Ther Drug Monit. 41:192–212. 2019.PubMed/NCBI View Article : Google Scholar

21 

Preijers T, Schütte LM, Kruip MJHA, Cnossen MH, Leebeek FWG, van Hest RM and Mathôt RAA: Population pharmacokinetics of clotting factor concentrates and desmopressin in hemophilia. Clin Pharmacokinet. 60:1–16. 2021.PubMed/NCBI View Article : Google Scholar

22 

Atiq F, Heijdra J, Snijders F, Boender J, Kempers E, van Heerde WL, Maas DPMSM, Krouwel S, Schoormans SC, de Meris J, et al: Desmopressin response depends on the presence and type of genetic variants in patients with type 1 and type 2 von Willebrand disease. Blood Adv. 6:5317–5326. 2022.PubMed/NCBI View Article : Google Scholar

23 

Trigg DE, Stergiotou I, Peitsidis P and Kadir RA: A systematic review: The use of desmopressin for treatment and prophylaxis of bleeding disorders in pregnancy. Haemophilia. 18:25–33. 2012.PubMed/NCBI View Article : Google Scholar

24 

Kouides PA, Byams VR, Philipp CS, Stein SF, Heit JA, Lukes AS, Skerrette NI, Dowling NF, Evatt BL, Miller CH, et al: Multisite management study of menorrhagia with abnormal laboratory haemostasis: A prospective crossover study of intranasal desmopressin and oral tranexamic acid. Br J Haematol. 145:212–220. 2009.PubMed/NCBI View Article : Google Scholar

25 

Saccullo G and Makris M: Prophylaxis in von Willebrand disease: Coming of age? Semin Thromb Hemost. 42:498–506. 2016.PubMed/NCBI View Article : Google Scholar

26 

Andersen LK, Hvas AM and Hvas CL: Effect of desmopressin on platelet dysfunction during antiplatelet therapy: A systematic review. Neurocrit Care. 34:1026–1046. 2021.PubMed/NCBI View Article : Google Scholar

27 

Benvenuto L, Qayum S, Kim H, Robbins H, Shah L, Dimango A, Magda G, Grewal H, Lemaitre P, Stanifer BP, et al: Lung transplantation for pulmonary fibrosis associated with hermansky-pudlak syndrome. A single-center experience. Transplant Direct. 8(e1303)2022.PubMed/NCBI View Article : Google Scholar

28 

Merideth MA, Introne WJ, Wang JA, O'Brien KJ, Huizing M and Gochuico BR: Genetic variants associated with Hermansky-Pudlak syndrome. Platelets. 31:544–547. 2020.PubMed/NCBI View Article : Google Scholar

29 

MacDonald S, Wright A, Beuche F, Downes K, Besser M, Symington E, Kelly A and Thomas W: Characterization of a large cohort of patients with unclassified bleeding disorder clinical features, management of haemostatic challenges and use of global haemostatic assessment with proposed recommendations for diagnosis and treatment. Int J Lab Hematol. 42:116–125. 2020.PubMed/NCBI View Article : Google Scholar

30 

Obaji S, Alikhan R, Rayment R, Carter P, Macartney N and Collins P: Unclassified bleeding disorders: Outcome of haemostatic challenges following tranexamic acid and/or desmopressin. Haemophilia. 22:285–291. 2016.PubMed/NCBI View Article : Google Scholar

31 

Czer LS, Bateman TM, Gray RJ, Raymond M, Stewart ME, Lee S, Goldfinger D, Chaux A and Matloff JM: Treatment of severe platelet dysfunction and hemorrhage after cardiopulmonary bypass: Reduction in blood product usage with desmopressin. J Am Coll Cardiol. 9:1139–1147. 1987.PubMed/NCBI View Article : Google Scholar

32 

Wademan BH and Galvin SD: Desmopressin for reducing postoperative blood loss and transfusion requirements following cardiac surgery in adults. Interact Cardiovasc Thorac Surg. 18:360–370. 2014.PubMed/NCBI View Article : Google Scholar

33 

Radhakrishnan S, Chanchlani R, Connolly B and Langlois V: Pre-procedure desmopressin acetate to reduce bleeding in renal failure: Does it really work? Nephron Clin Pract. 128:45–48. 2014.PubMed/NCBI View Article : Google Scholar

34 

Athavale A, Kulkarni H, Arslan CD and Hart P: Desmopressin and bleeding risk after percutaneous kidney biopsy. BMC Nephrol. 20(413)2019.PubMed/NCBI View Article : Google Scholar

35 

Akbarpour M, Jalali MM, Akbari M, Haddadi S and Fani G: Effect of desmopressin on bleeding during endoscopic sinus surgery: A randomized clinical trial. Laryngoscope Investig Otolaryngol. 7:920–927. 2022.PubMed/NCBI View Article : Google Scholar

36 

Haddady-Abianeh S, Rajabpour AA, Sanatkarfar M, Farahvash MR, Khorasani G and Molaei H: The hemostatic effect of desmopressin on bleeding as a nasal spray in open septorhinoplasty. Aesthetic Plast Surg. 43:1603–1606. 2019.PubMed/NCBI View Article : Google Scholar

37 

Jahanshahi J, Tayebi E, Hashemian F, Bakhshaei MH, Ahmadi MS and Rabiei MA: Effect of local desmopressin administration on intraoperative blood loss and quality of the surgical field during functional endoscopic sinus surgery in patients with chronic rhinosinusitis: A triple-blinded clinical trial. Eur Arch Otorhinolaryngol. 276:1995–1999. 2019.PubMed/NCBI View Article : Google Scholar

38 

Safaeian R, Hassani V, Ghandi A and Mohseni M: Desmopressin nasal spray reduces blood loss and improves the quality of the surgical field during functional endoscopic sinus surgery. J Anaesthesiol Clin Pharmacol. 37:261–265. 2021.PubMed/NCBI View Article : Google Scholar

39 

Shao H, Kuang LT, Hou WJ and Zhang T: Effect of desmopressin administration on intraoperative blood loss and quality of the surgical field during functional endoscopic sinus surgery: A randomized, clinical trial. BMC Anesthesiol. 15(53)2015.PubMed/NCBI View Article : Google Scholar

40 

Frontera JA, Lewin JJ III, Rabinstein AA, Aisiku IP, Alexandrov AW, Cook AM, Del Zoppo GJ, Kumar M, Peerschke EI, Stiefel MF, et al: Guideline for reversal of antithrombotics in intracranial hemorrhage: Executive summary. A statement for healthcare professionals from the neurocritical care society and the society of critical care medicine. Crit Care Med. 44:2251–2257. 2016.PubMed/NCBI View Article : Google Scholar

41 

Mengel A, Stefanou MI, Hadaschik KA, Wolf M, Stadler V, Poli K, Lindig T, Ernemann U, Grimm F, Tatagiba M, et al: Early administration of Desmopressin and platelet transfusion for reducing hematoma expansion in patients with acute antiplatelet therapy associated Intracerebral Hemorrhage. Crit Care Med. 48:1009–1017. 2020.PubMed/NCBI View Article : Google Scholar

42 

Loggini A, El Ammar F, Darzi AJ, Mansour A, Kramer CL, Goldenberg FD and Lazaridis C: Effect of desmopressin on hematoma expansion in antiplatelet-associated intracerebral hemorrhage: A systematic review and meta-analysis. J Clin Neurosci. 86:116–121. 2021.PubMed/NCBI View Article : Google Scholar

43 

Bultitude M and Rees J: Management of renal colic. BMJ. 345(e5499)2012.PubMed/NCBI View Article : Google Scholar

44 

Golzari SE, Soleimanpour H, Rahmani F, Mehr NZ, Safari S, Heshmat Y and Bakhtavar HE: Therapeutic approaches for renal colic in the emergency department: A review article. Anesth Pain Med. 4(e16222)2014.PubMed/NCBI View Article : Google Scholar

45 

Kapila V, Kapila AK, Tailly T, Rappe B, Juul KV and Everaert K: The analgesic action of desmopressin in renal colic. Acta Clin Belg. 72:179–185. 2017.PubMed/NCBI View Article : Google Scholar

46 

Patti L and Leslie SW: Acute renal colic. StatPearls Publishing, 2022.

47 

Juul KV, Schroeder MK, Rittig S and Nørgaard JP: Desmopressin as an adjuvant to opioids or NSAIDs in treatment of renal colic: A nationwide register-based study. Pharmacoepidemiol Drug Saf. 24:1155–1160. 2015.PubMed/NCBI View Article : Google Scholar

48 

Amer T, Osman B, Johnstone A, Mariappan M, Gupta A, Brattis N, Jones G, Somani BK, Keeley FX Jr and Aboumarzouk OM: Medical expulsive therapy for ureteric stones: Analysing the evidence from systematic reviews and meta-analysis of powered double-blinded randomised controlled trials. Arab J Urol. 15:83–93. 2017.PubMed/NCBI View Article : Google Scholar

49 

Campschroer T, Zhu X, Vernooij RW and Lock MT: Alpha-blockers as medical expulsive therapy for ureteral stones. Cochrane Database Syst Rev. 5(CD08509)2018.PubMed/NCBI View Article : Google Scholar

50 

Lim I, Sellers DJ and Chess-Williams R: Current and emerging pharmacological targets for medical expulsive therapy. Basic Clin Pharmacol Toxicol. 130 (Suppl 1):S16–S22. 2022.PubMed/NCBI View Article : Google Scholar

51 

European Association of Urology (EAU): EAU Guidelines on Urolithiasis. EAU, Arnhem, 2024. https://d56bochluxqnz.cloudfront.net/documents/full-guideline/EAU-Guidelines-on-Urolithiasis-2024.pdf.

52 

Jalili M, Shirani F, Entezari P, Hedayatshodeh M, Baigi V and Mirfazaelian H: Desmopressin/indomethacin combination efficacy and safety in renal colic pain management: A randomized placebo controlled trial. Am J Emerg Med. 37:1009–1012. 2019.PubMed/NCBI View Article : Google Scholar

53 

Kimoto Y and Constantinou CE: Effects of [1-desamino-8-D-arginine]vasopressin and papaverine on rabbit renal pelvis. Eur J Pharmacol. 175:359–362. 1990.PubMed/NCBI View Article : Google Scholar

54 

el-Sherif AE, Salem M, Yahia H, al-Sharkawy WA and al-Sayrafi M: Treatment of renal colic by desmopressin intranasal spray and diclofenac sodium. J Urol. 153:1395–1398. 1995.PubMed/NCBI

55 

Hazhir S, Badr YAA and Darabi JN: Comparison of intranasal desmopressin and intramuscular tramadol versus pethidine in patients with renal colic. Urol J. 7:148–151. 2010.PubMed/NCBI View Article : Google Scholar

56 

Kheirollahi AR, Tehrani M and Bashashati M: A comparison of the effect of intranasal desmopressin and intramuscular hyoscine N-butyl bromide combination with intramuscular hyoscine N-butyl bromide alone in acute renal colic. J Res Med Sci. 15:214–218. 2010.PubMed/NCBI

57 

Roshani A, Falahatkar S, Khosropanah I, Roshan ZA, Zarkami T, Palizkar M, Emadi SA, Akbarpour M and Khaki N: Assessment of clinical efficacy of intranasal desmopressin spray and diclofenac sodium suppository in treatment of renal colic versus diclofenac sodium alone. Urology. 75:540–542. 2010.PubMed/NCBI View Article : Google Scholar

58 

Masoumi K, Darian AS, Forouzan A, Barzegari H, Rahim F, Feli M, Sheidaii MF and Porozan S: The efficacy of intranasal desmopressin as an adjuvant in the acute renal colic pain management. Pain Res Treat. 2014(320327)2014.PubMed/NCBI View Article : Google Scholar

59 

Shirvani MK, Mahboub MD, Ghazi M and Delijani A: A comparison of the effects of morphine and sublingual desmopressin combination therapy with morphine alone in treatment of renal colic: A controlled clinical trial. Urol J. 12:2001–2004. 2015.PubMed/NCBI

60 

Shirazi M, Salehipour M, Afrasiabi MA and Aminsharifi A: Analgesic effects and safety of desmopressin, tramadol and indomethacin in patients with acute renal colic; A randomized clinical trial. Bull Emerg Trauma. 3:41–45. 2015.PubMed/NCBI

61 

Dolatabadi AA, Memary E, Kariman H, Gigloo KN and Baratloo A: Intranasal desmopressin compared with intravenous ketorolac for pain management of patients with renal colic referring to the emergency department: A randomized clinical trial. Anesth Pain Med. 7(e43595)2017.PubMed/NCBI View Article : Google Scholar

62 

Ghafouri HB, Abazarian N, Yasinzadeh M and Modirian E: Intravenous paracetamol vs intranasal desmopressin for renal colic in the emergency department: A randomized clinical trial. Pain Med. 21:3437–3442. 2020.PubMed/NCBI View Article : Google Scholar

63 

Pricop C, Branisteanu DD, Orsolya M, Puia D, Matei A and Checherita IA: Sublingual desmopressin is efficient and safe in the therapy of lithiasic renal colic. Int Urol Nephrol. 48:183–189. 2016.PubMed/NCBI View Article : Google Scholar

64 

Kumar S, Behera NC, Sarkar D, Prasad S, Mandal AK and Singh SK: A comparative assessment of the clinical efficacy of intranasal desmopressin spray and diclofenac in the treatment of renal colic. Urol Res. 39:397–400. 2011.PubMed/NCBI View Article : Google Scholar

65 

Lopes T, Dias JS, Marcelino J, Varela J, Ribeiro S and Dias J: An assessment of the clinical efficacy of intranasal desmopressin spray in the treatment of renal colic. BJU Int. 87:322–325. 2001.PubMed/NCBI View Article : Google Scholar

66 

Jalili M, Entezari P, Doosti-Irani A, Masoomi R and Mirfazaelian H: Desmopressin effectiveness in renal colic pain management: Systematic review and meta-analysis. Am J Emerg Med. 34:1535–1541. 2016.PubMed/NCBI View Article : Google Scholar

67 

Seghatoleslami G, Jahromi MS, Farzaneh R, Rahsepar S, Malekshoar M, Vatankhah M, Akhavan R, Abbasi B, Akhavan H, Abiri S, et al: Alternative medical interventions versus conventional treatment of renal colic: An updated systematic review and network meta-analysis. Urol J. 19:412–419. 2022.PubMed/NCBI View Article : Google Scholar

68 

Kreek MJ, Zhou Y and Levran O: Functions of arginine vasopressin and its receptors: Importance of human molecular genetics studies in bidirectional translational research. Biol Psychiatry. 70:502–503. 2011.PubMed/NCBI View Article : Google Scholar

69 

Albers HE: The regulation of social recognition, social communication and aggression: Vasopressin in the social behavior neural network. Horm Behav. 61:283–292. 2012.PubMed/NCBI View Article : Google Scholar

70 

Winter J and Jurek B: The interplay between oxytocin and the CRF system: Regulation of the stress response. Cell Tissue Res. 375:85–91. 2019.PubMed/NCBI View Article : Google Scholar

71 

Marsh N, Marsh AA, Lee MR and Hurlemann R: Oxytocin and the neurobiology of prosocial behavior. Neuroscientist. 27:604–619. 2021.PubMed/NCBI View Article : Google Scholar

72 

Müller D, Florkowski H, Chavez-Kattau K, Carlsson G and Eggert P: The effect of desmopressin on short-term memory in children with primary nocturnal enuresis. J Urol. 166:2432–2434. 2001.PubMed/NCBI

73 

Schulz-Juergensen S, Rieger M, Schaefer J, Neusuess A and Eggert P: Effect of 1-desamino-8-D-arginine vasopressin on prepulse inhibition of startle supports a central etiology of primary monosymptomatic enuresis. J Pediatr. 151:571–574. 2007.PubMed/NCBI View Article : Google Scholar

74 

Laczi F, Valkusz Z, Lászlo FA, Wagner A, Járdánházy T, Szász A, Szilárd J and Telegdy G: Effects of lysine-vasopressin and 1-deamino-8-D-arginine-vasopressin on memory in healthy individuals and diabetes insipidus patients. Psychoneuroendocrinology. 7:185–193. 1982.PubMed/NCBI View Article : Google Scholar

75 

EMBL-EBI: Expression Atlas-gene expression across species and biological conditions. https://www.ebi.ac.uk/gxa/home. Last accessed 12 July, 2023.

76 

Charles R, Sakurai T, Takahashi N, Elder GA, Sosa MA, Young LJ and Buxbaum JD: Introduction of the human AVPR1A gene substantially alters brain receptor expression patterns and enhances aspects of social behavior in transgenic mice. Dis Model Mech. 7:1013–1022. 2014.PubMed/NCBI View Article : Google Scholar

77 

Ebstein RP, Knafo A, Mankuta D, Chew SH and Lai PS: The contributions of oxytocin and vasopressin pathway genes to human behavior. Horm Behav. 61:359–379. 2012.PubMed/NCBI View Article : Google Scholar

78 

GTEX Consortium. Ardlie KG, Deluca DS, Segrè AV, Sullivan TJ, Young T, Gelfand ET, Trowbridge C, Maller JB, Tukiainen T, et al: The genotype-tissue expression (GTEx) pilot analysis: Multitissue gene regulation in humans. Science. 348:648–660. 2015.PubMed/NCBI View Article : Google Scholar

79 

Vargas KJ, Sarmiento JM, Ehrenfeld P, Añazco CC, Villanueva CI, Carmona PL, Brenet M, Navarro J, Müller-Esterl W and González CB: Postnatal expression of V2 vasopressin receptor splice variants in the rat cerebellum. Differentiation. 77:377–385. 2009.PubMed/NCBI View Article : Google Scholar

80 

Kato Y, Igarashi N, Hirasawa A, Tsujimoto G and Kobayashi M: Distribution and developmental changes in vasopressin V2 receptor mRNA in rat brain. Differentiation. 59:163–169. 1995.PubMed/NCBI View Article : Google Scholar

81 

Schmahmann JD: Emotional disorders and the cerebellum: Neurobiological substrates, neuropsychiatry, and therapeutic implications. Handb Clin Neurol. 183:109–154. 2021.PubMed/NCBI View Article : Google Scholar

82 

Tomlinson SP, Davis NJ, Morgan HM and Bracewell RM: Cerebellar contributions to verbal working memory. Cerebellum. 13:354–361. 2014.PubMed/NCBI View Article : Google Scholar

83 

Sakai Y, Horiba N, Tozawa F, Sakai K, Kuwayama A, Demura H and Suda T: Desmopressin stimulation test for diagnosis of ACTH-dependent Cushing's syndrome. Endocr J. 44:687–695. 1997.PubMed/NCBI View Article : Google Scholar

84 

Vassiliadi DA and Tsagarakis S: Diagnosis of Endocrine Disease: The role of the desmopressin test in the diagnosis and follow-up of Cushing's syndrome. Eur J Endocrinol. 178:R201–R214. 2018.PubMed/NCBI View Article : Google Scholar

85 

Jonat S, Santer R, Schneppenheim R, Obser T and Eggert P: Effect of DDAVP on nocturnal enuresis in a patient with nephrogenic diabetes insipidus. Arch Dis Child. 81:57–59. 1999.PubMed/NCBI View Article : Google Scholar

86 

Robben JH, Sze M, Knoers NV, Eggert P, Deen P and Müller D: Relief of nocturnal enuresis by desmopressin is kidney and vasopressin type 2 receptor independent. J Am Soc Nephrol. 18:1534–1539. 2007.PubMed/NCBI View Article : Google Scholar

87 

Stegner H, Artman HG, Leake RD and Fisher DA: Does DDAVP (1-desamino-8-D-arginine-vasopressin) cross the blood-CSF barrier? Neuroendocrinology. 37:262–265. 1983.PubMed/NCBI View Article : Google Scholar

88 

Sørensen PS, Vilhardt H, Gjerris F and Warberg J: Impermeability of the blood-cerebrospinal fluid barrier to 1-deamino-8-D-arginine-vasopressin (DDAVP) in patients with acquired, communicating hydrocephalus. Eur J Clin Invest. 14:435–439. 1984.PubMed/NCBI View Article : Google Scholar

89 

Ferring Pharmaceuticals: DDAVP Tablets 0.2mg SmPC, 2012.

90 

Banks WA, Kastin AJ, Horvath A and Michals EA: Carrier-mediated transport of vasopressin across the blood-brain barrier of the mouse. J Neurosci Res. 18:326–332. 1987.PubMed/NCBI View Article : Google Scholar

91 

Su Y, Sun B, Gao X, Dong X, Fu L, Zhang Y, Li Z, Wang Y, Jiang H and Han B: Intranasal delivery of targeted nanoparticles loaded with miR-132 to brain for the treatment of neurodegenerative diseases. Front Pharmacol. 11(1165)2020.PubMed/NCBI View Article : Google Scholar

92 

Lochhead JJ, Kellohen KL, Ronaldson PT and Davis TP: Distribution of insulin in trigeminal nerve and brain after intranasal administration. Sci Rep. 9(2621)2019.PubMed/NCBI View Article : Google Scholar

93 

Maeng J and Lee K: Systemic and brain delivery of antidiabetic peptides through nasal administration using cell-penetrating peptides. Front Pharmacol. 13(1068495)2022.PubMed/NCBI View Article : Google Scholar

94 

Hallschmid M: Intranasal insulin for Alzheimer's disease. CNS Drugs. 35:21–37. 2021.PubMed/NCBI View Article : Google Scholar

95 

Mutsuga N, Shahar T, Verbalis JG, Xiang CC, Brownstein MJ and Gainer H: Regulation of gene expression in magnocellular neurons in rat supraoptic nucleus during sustained hypoosmolality. Endocrinology. 146:1254–1267. 2005.PubMed/NCBI View Article : Google Scholar

96 

Landgraf R, Hess J and Hartmann E: Effect of oxytocin on regional 3H-orotic acid uptake in rat brain. Endokrinologie. 70:45–52. 1977.PubMed/NCBI(In German).

97 

Landgraf R, Hess J and Ermisch A: The influence of vasopressin on the regional uptake of [3H] orotic acid by rat brain. Acta Biol Med Ger. 37:655–658. 1978.PubMed/NCBI

98 

Burbach JP, Kovács GL, de Wied D, van Nispen JW and Greven HM: A major metabolite of arginine vasopressin in the brain is a highly potent neuropeptide. Science. 221:1310–1312. 1983.PubMed/NCBI View Article : Google Scholar

99 

Burbach JP, Bohus B, Kovács GL, Van Nispen JW, Greven HM and De Wied D: Oxytocin is a precursor of potent behaviourally active neuropeptides. Eur J Pharmacol. 94:125–131. 1983.PubMed/NCBI View Article : Google Scholar

100 

van Bree JB, de Boer AG, Verhoef JC, Danhof M and Breimer DD: Transport of vasopressin fragments across the blood-brain barrier: In vitro studies using monolayer cultures of bovine brain endothelial cells. J Pharmacol Exp Ther. 249:901–905. 1989.PubMed/NCBI

101 

Lee MR and Jayant RD: Penetration of the blood-brain-barrier by peripheral neuropeptides: New approaches to enhancing transport and endogenous expression. Cell Tissue Res. 375:287–293. 2019.PubMed/NCBI View Article : Google Scholar

102 

Lal S, Nair NP, Isaac I, Thavundayil J and Guyda H: Effect of some peptides on dopaminergic function in man. J Neural Transm Suppl. 29:173–181. 1990.PubMed/NCBI View Article : Google Scholar

103 

Brambilla F, Aguglia E, Massironi R, Maggioni M, Grillo W, Castiglioni R, Catalano M and Drago F: Neuropeptide therapies in chronic schizophrenia: TRH and vasopressin administration. Neuropsychobiology. 15:114–121. 1986.PubMed/NCBI View Article : Google Scholar

104 

Brambilla F, Bondiolotti GP, Maggioni M, Sciascia A, Grillo W, Sanna F, Latina A and Picotti GB: Vasopressin (DDAVP) therapy in chronic schizophrenia: Effects on negative symptoms and memory. Neuropsychobiology. 20:113–119. 1989.PubMed/NCBI View Article : Google Scholar

105 

Pifano M, Garona J, Capobianco CS, Gonzalez N, Alonso DF and Ripoll GV: Peptide agonists of vasopressin V2 receptor reduce expression of neuroendocrine markers and tumor growth in human lung and prostate tumor cells. Front Oncol. 7(11)2017.PubMed/NCBI View Article : Google Scholar

106 

Keegan BP, Akerman BL, Péqueux C and North WG: Provasopressin expression by breast cancer cells: Implications for growth and novel treatment strategies. Breast Cancer Res Treat. 95:265–277. 2006.PubMed/NCBI View Article : Google Scholar

107 

Sobol NT, Solernó LM, Beltrán B, Vásquez L, Ripoll GV, Garona J and Alonso DF: Anticancer activity of repurposed hemostatic agent desmopressin on AVPR2-expressing human osteosarcoma. Exp Ther Med. 21(566)2021.PubMed/NCBI View Article : Google Scholar

108 

Bass R, Roberto D, Wang DZ, Cantu FP, Mohamadi RM, Kelley SO, Klotz L and Venkateswaran V: Combining desmopressin and docetaxel for the treatment of castration-resistant prostate cancer in an orthotopic model. Anticancer Res. 39:113–118. 2019.PubMed/NCBI View Article : Google Scholar

109 

Weinberg RS, Grecco MO, Ferro GS, Seigelshifer DJ, Perroni NV, Terrier FJ, Sánchez-Luceros A, Maronna E, Sánchez-Marull R, Frahm I, et al: A phase II dose-escalation trial of perioperative desmopressin (1-desamino-8-d-arginine vasopressin) in breast cancer patients. Springerplus. 4(428)2015.PubMed/NCBI View Article : Google Scholar

110 

Iseas S, Roca EL, O'Connor JM, Eleta M, Sanchez-Luceros A, Di Leo D, Tinelli M, Fara ML, Spitzer E, Demarco IA, et al: Administration of the vasopressin analog desmopressin for the management of bleeding in rectal cancer patients: Results of a phase I/II trial. Invest New Drugs. 38:1580–1587. 2020.PubMed/NCBI View Article : Google Scholar

111 

Hermo GA, Torres P, Ripoll GV, Scursoni AM, Gomez DE, Alonso DF and Gobello C: Perioperative desmopressin prolongs survival in surgically treated bitches with mammary gland tumours: A pilot study. Vet J. 178:103–108. 2008.PubMed/NCBI View Article : Google Scholar

112 

Ikeda Y, Zabbarova I, de Rijk M, Kanai A, Wolf-Johnston A, Weiss JP, Jackson E and Birder L: Effects of vasopressin receptor agonists on detrusor smooth muscle tone in young and aged bladders: Implications for nocturia treatment. Continence (Amst). 2022(100032)2022.PubMed/NCBI View Article : Google Scholar

113 

Papatheodorou I, Moreno P, Manning J, Fuentes AM, George N, Fexova S, Fonseca NA, Füllgrabe A, Green M, Huang N, et al: Expression atlas update: From tissues to single cells. Nucl Acids Res. 48:D77–D83. 2020.PubMed/NCBI View Article : Google Scholar

114 

Oiso Y, Robertson GL, Nørgaard JP and Juul KV: Clinical review: Treatment of neurohypophyseal diabetes insipidus. J Clin Endocrinol Metab. 98:3958–3967. 2013.PubMed/NCBI View Article : Google Scholar

115 

Altun G, Hemşinli D, Pulathan Z and Civelek A: Emergency coronary bypass surgery in patients under the influence of dualantiplatelet therapy: Effects of tranexamic acid and desmopressin acetate. Turk J Med Sci. 47:doi: 10.3906/sag-1612-140. 2017.PubMed/NCBI View Article : Google Scholar

116 

Bignami E, Cattaneo M, Crescenzi G, Ranucci M, Guarracino F, Cariello C, Baldassarri R, Isgrò G, Baryshnikova E, Fano G, et al: Desmopressin after cardiac surgery in bleeding patients. A multicenter randomized trial. Acta Anaesthesiol Scand. 60:892–900. 2016.PubMed/NCBI View Article : Google Scholar

117 

Jahangirifard A, Razavi MR, Ahmadi ZH and Forozeshfard M: Effect of desmopressin on the amount of bleeding and transfusion requirements in patients undergoing heart transplant surgery. Basic Clin Pharmacol Toxicol. 121:175–180. 2017.PubMed/NCBI View Article : Google Scholar

118 

Jin L and Ji HW: Effect of desmopressin on platelet aggregation and blood loss in patients undergoing valvular heart surgery. Chin Med J. 128:644–647. 2015.PubMed/NCBI View Article : Google Scholar

119 

Mirmansoori A, Farzi F, Sedighinejad A, Imantalab V, Mohammadzadeh A, Roushan ZA, Tehran SZ, Nemati M and Dehghan A: The effect of desmopressin on the amount of bleeding in patients undergoing coronary artery bypass graft surgery with a cardiopulmonary bypass pump after taking anti-platelet medicine. Anesth Pain Med. 6(e39226)2016.PubMed/NCBI View Article : Google Scholar

120 

Cheong M, Lee TY, Lee J and Kim SB: No effect of desmopressin administration before kidney biopsy on the risk of major post-biopsy bleeding. Nefrologia (Engl Ed). 26:S0211–S6995. 2021.PubMed/NCBI View Article : Google Scholar : (In English, Spanish).

121 

Leclerc S, Nadeau-Fredette AC, Elftouh N, Lafrance JP, Pichette V and Laurin LP: Use of desmopressin prior to kidney biopsy in patients with high bleeding risk. Kidney Int Rep. 5:1180–1187. 2020.PubMed/NCBI View Article : Google Scholar

122 

Wang LC, Hu YF, Chen L, Xing R, Lin XF and Kou QY: Desmopressin acetate decreases blood loss in patients with massive hemorrhage undergoing gastrointestinal surgery. Turk J Gastroenterol. 31:474–481. 2020.PubMed/NCBI View Article : Google Scholar

123 

Anderson LT, David R, Bonnet K and Dancis J: Passive avoidance learning in Lesch-Nyhan disease: Effect of 1-desamino-8-arginine-vasopressin. Life Sci. 24:905–910. 1979.PubMed/NCBI View Article : Google Scholar

124 

Beckwith BE, Petros T, Kanaan-Beckwith S, Couk DI, Haug RJ and Ryan C: Vasopressin analog (DDAVP) facilitates concept learning in human males. Peptides. 3:627–630. 1982.PubMed/NCBI View Article : Google Scholar

125 

Eisenberg J, Hamburger-Bar R and Belmaker RH: The effect of vasopressin treatment on learning in Down's syndrome. J Neural Transm. 60:143–147. 1984.PubMed/NCBI View Article : Google Scholar

126 

Beckwith BE, Petros TV, Bergloff PJ and Staebler RJ: Vasopressin analogue (DDAVP) facilitates recall of narrative prose. Behav Neurosci. 101:429–432. 1987.PubMed/NCBI View Article : Google Scholar

127 

Beckwith BE, Petros TV, Bergloff PJ, Swenson RR and Paulson R: Failure of posttrial administration of vasopressin analogue (DDAVP) to influence memory in healthy, young, male volunteers. Peptides. 16:1327–1328. 1995.PubMed/NCBI View Article : Google Scholar

128 

Beckwith BE, Till RE, Reno CR and Poland RE: Dose-dependent effects of DDAVP on memory in healthy young adult males: A preliminary study. Peptides. 11:473–476. 1990.PubMed/NCBI View Article : Google Scholar

129 

Eisenhofer G, Lambie DG and Robinson BJ: No improvement in ethanol-induced memory deficits after administration of a vasopressin analog. Life Sci. 37:2499–2505. 1985.PubMed/NCBI View Article : Google Scholar

130 

Guard O, Marchal G, Graule A, Dumas R and D'Athis P: Effects of vasopressin and desmopressin on memory. A double-blind study in 40 healthy volunteers. Neuropsychobiology. 15:80–83. 1986.PubMed/NCBI View Article : Google Scholar

131 

Jenkins JS, Mather HM and Coughlan AK: Effect of desmopressin on normal and impaired memory. J Neurol Neurosurg Psychiatry. 45:830–831. 1982.PubMed/NCBI View Article : Google Scholar

132 

Millar K, Jeffcoate WJ and Walder CP: Vasopressin and memory: Improvement in normal short-term recall and reduction of alcohol-induced amnesia. Psychol Med. 17:335–341. 1987.PubMed/NCBI View Article : Google Scholar

133 

Nebes RD, Reynolds CF III and Horn LC: The effect of vasopressin on memory in the healthy elderly. Psychiatry Res. 11:49–59. 1984.PubMed/NCBI View Article : Google Scholar

134 

Till RE and Beckwith BE: Sentence memory affected by vasopressin analog (DDAVP) in cross-over experiment. Peptides. 6:397–402. 1985.PubMed/NCBI View Article : Google Scholar

135 

Weingartner H, Gold P, Ballenger JC, Smallberg SA, Summers R, Rubinow DR, Post RM and Goodwin FK: Effects of vasopressin on human memory functions. Science. 211:601–603. 1981.PubMed/NCBI View Article : Google Scholar

136 

Abdollahian E, Sargolzaee MR, Hajzade M, Mohebbi MD and Javanbakht A: Effects of desmopressin (DDAVP) on memory impairment following electroconvulsive therapy (ECT). Acta Neuropsychiatr. 16:130–137. 2004.PubMed/NCBI View Article : Google Scholar

137 

Lerer B, Zabow T, Egnal N and Belmaker RH: Effect of vasopressin on memory following electroconvulsive therapy. Biol Psychiatry. 18:821–824. 1983.PubMed/NCBI

138 

Beckwith BE, Couk DI and Till TS: Vasopressin analog influences the performance of males on a reaction time task. Peptides. 4:707–709. 1983.PubMed/NCBI View Article : Google Scholar

139 

Jennings JR, Nebes RD and Reynolds CF III: Vasopressin peptide (DDAVP) may narrow the focus of attention in normal elderly. Psychiatry Res. 17:31–39. 1986.PubMed/NCBI View Article : Google Scholar

140 

Tsikunov SG and Belokoskova SG: Psychophysiological analysis of the influence of vasopressin on speech in patients with post-stroke aphasias. Span J Psychol. 10:178–188. 2007.PubMed/NCBI View Article : Google Scholar

141 

Gold PW, Weingartner H, Ballenger JC, Goodwin FK and Post RM: Effects of 1-desamo-8-D-arginine vasopressin on behaviour and cognition in primary affective disorder. Lancet. 2:992–994. 1979.PubMed/NCBI View Article : Google Scholar

142 

Hosseini SMR, Farokhnia M, Rezaei F, Gougol A, Yekehtaz H, Iranpour N, Salehi B, Tabrizi M, Tajdini M, Ghaleiha A and Akhondzadeh S: Intranasal desmopressin as an adjunct to risperidone for negative symptoms of schizophrenia: A randomized, double-blind, placebo-controlled, clinical trial. Eur Neuropsychopharmacology. 24:846–855. 2014.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Everaert K, Holm‑Larsen T, Bou Kheir G, Rottey S, Weiss JP, Vande Walle J, Kabarriti AE, Dossche L, Hervé F, Spinoit A, Spinoit A, et al: Potential clinical applications of current and future oral forms of desmopressin (Review). Exp Ther Med 28: 303, 2024.
APA
Everaert, K., Holm‑Larsen, T., Bou Kheir, G., Rottey, S., Weiss, J.P., Vande Walle, J. ... Juul, K.V. (2024). Potential clinical applications of current and future oral forms of desmopressin (Review). Experimental and Therapeutic Medicine, 28, 303. https://doi.org/10.3892/etm.2024.12592
MLA
Everaert, K., Holm‑Larsen, T., Bou Kheir, G., Rottey, S., Weiss, J. P., Vande Walle, J., Kabarriti, A. E., Dossche, L., Hervé, F., Spinoit, A., Nørgaard, J., Juul, K. V."Potential clinical applications of current and future oral forms of desmopressin (Review)". Experimental and Therapeutic Medicine 28.2 (2024): 303.
Chicago
Everaert, K., Holm‑Larsen, T., Bou Kheir, G., Rottey, S., Weiss, J. P., Vande Walle, J., Kabarriti, A. E., Dossche, L., Hervé, F., Spinoit, A., Nørgaard, J., Juul, K. V."Potential clinical applications of current and future oral forms of desmopressin (Review)". Experimental and Therapeutic Medicine 28, no. 2 (2024): 303. https://doi.org/10.3892/etm.2024.12592
Copy and paste a formatted citation
x
Spandidos Publications style
Everaert K, Holm‑Larsen T, Bou Kheir G, Rottey S, Weiss JP, Vande Walle J, Kabarriti AE, Dossche L, Hervé F, Spinoit A, Spinoit A, et al: Potential clinical applications of current and future oral forms of desmopressin (Review). Exp Ther Med 28: 303, 2024.
APA
Everaert, K., Holm‑Larsen, T., Bou Kheir, G., Rottey, S., Weiss, J.P., Vande Walle, J. ... Juul, K.V. (2024). Potential clinical applications of current and future oral forms of desmopressin (Review). Experimental and Therapeutic Medicine, 28, 303. https://doi.org/10.3892/etm.2024.12592
MLA
Everaert, K., Holm‑Larsen, T., Bou Kheir, G., Rottey, S., Weiss, J. P., Vande Walle, J., Kabarriti, A. E., Dossche, L., Hervé, F., Spinoit, A., Nørgaard, J., Juul, K. V."Potential clinical applications of current and future oral forms of desmopressin (Review)". Experimental and Therapeutic Medicine 28.2 (2024): 303.
Chicago
Everaert, K., Holm‑Larsen, T., Bou Kheir, G., Rottey, S., Weiss, J. P., Vande Walle, J., Kabarriti, A. E., Dossche, L., Hervé, F., Spinoit, A., Nørgaard, J., Juul, K. V."Potential clinical applications of current and future oral forms of desmopressin (Review)". Experimental and Therapeutic Medicine 28, no. 2 (2024): 303. https://doi.org/10.3892/etm.2024.12592
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team