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Article Open Access

Risk factors for infectious complications after gastrectomy in older patients

  • Authors:
    • Michihisa Iida
    • Shigeru Takeda
    • Tsunenori Yamamoto
    • Chiyo Nakashima
    • Mitsuo Nishiyama
    • Yusaku Watanabe
    • Yoshitaro Shindo
    • Yukio Tokumitsu
    • Shinobu Tomochika
    • Yuki Nakagami
    • Hidenori Takahashi
    • Hiroaki Nagano
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755‑8505, Japan, Department of Data Science, Faculty of Data Science, Shimonoseki City University, Shimonoseki, Yamaguchi 751‑8510, Japan
    Copyright: © Iida et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 319
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    Published online on: June 17, 2024
       https://doi.org/10.3892/etm.2024.12608
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Abstract

The present study aimed to identify preoperative and perioperative risk factors for postoperative infectious complications in older patients with gastric cancer. The present retrospective study included 504 patients with gastric cancer aged >65 years who underwent radical gastrectomy. After determining the cutoff values for various perioperative factors in the receiver operating characteristic curve analysis, preoperative and perioperative risk factors for the development of infectious complications after gastrectomy were examined using logistic regression analysis. Of the 504 patients who underwent gastrectomy, 95 (18.8%) developed infectious complications of grade II‑V based on the Clavien‑Dindo classification. In an analysis restricted to preoperative factors, male sex, low prognostic nutritional index, high visceral fat area and total gastrectomy were independent risk factors for infectious complications after gastrectomy. Among all perioperative factors, a low prognostic nutritional index and long operative duration were identified as independent risk factors for infectious complications after gastrectomy. The patients were divided into five groups according to the number of positive preoperative risk factors for infectious complications, and the incidence of infectious complications differed among the five groups (0 factors, 6.7%; 1 factor, 10.4%; 2 factors, 18.9%; 3 factors, 27.8%; and 4 factors, 47.6%; P<0.001). Older patients with gastric cancer who have a number of preoperative risk factors require careful consideration of the indication for gastrectomy and a shorter operative time to reduce infectious complications.
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Copy and paste a formatted citation
Spandidos Publications style
Iida M, Takeda S, Yamamoto T, Nakashima C, Nishiyama M, Watanabe Y, Shindo Y, Tokumitsu Y, Tomochika S, Nakagami Y, Nakagami Y, et al: Risk factors for infectious complications after gastrectomy in older patients. Exp Ther Med 28: 319, 2024.
APA
Iida, M., Takeda, S., Yamamoto, T., Nakashima, C., Nishiyama, M., Watanabe, Y. ... Nagano, H. (2024). Risk factors for infectious complications after gastrectomy in older patients. Experimental and Therapeutic Medicine, 28, 319. https://doi.org/10.3892/etm.2024.12608
MLA
Iida, M., Takeda, S., Yamamoto, T., Nakashima, C., Nishiyama, M., Watanabe, Y., Shindo, Y., Tokumitsu, Y., Tomochika, S., Nakagami, Y., Takahashi, H., Nagano, H."Risk factors for infectious complications after gastrectomy in older patients". Experimental and Therapeutic Medicine 28.2 (2024): 319.
Chicago
Iida, M., Takeda, S., Yamamoto, T., Nakashima, C., Nishiyama, M., Watanabe, Y., Shindo, Y., Tokumitsu, Y., Tomochika, S., Nakagami, Y., Takahashi, H., Nagano, H."Risk factors for infectious complications after gastrectomy in older patients". Experimental and Therapeutic Medicine 28, no. 2 (2024): 319. https://doi.org/10.3892/etm.2024.12608
Copy and paste a formatted citation
x
Spandidos Publications style
Iida M, Takeda S, Yamamoto T, Nakashima C, Nishiyama M, Watanabe Y, Shindo Y, Tokumitsu Y, Tomochika S, Nakagami Y, Nakagami Y, et al: Risk factors for infectious complications after gastrectomy in older patients. Exp Ther Med 28: 319, 2024.
APA
Iida, M., Takeda, S., Yamamoto, T., Nakashima, C., Nishiyama, M., Watanabe, Y. ... Nagano, H. (2024). Risk factors for infectious complications after gastrectomy in older patients. Experimental and Therapeutic Medicine, 28, 319. https://doi.org/10.3892/etm.2024.12608
MLA
Iida, M., Takeda, S., Yamamoto, T., Nakashima, C., Nishiyama, M., Watanabe, Y., Shindo, Y., Tokumitsu, Y., Tomochika, S., Nakagami, Y., Takahashi, H., Nagano, H."Risk factors for infectious complications after gastrectomy in older patients". Experimental and Therapeutic Medicine 28.2 (2024): 319.
Chicago
Iida, M., Takeda, S., Yamamoto, T., Nakashima, C., Nishiyama, M., Watanabe, Y., Shindo, Y., Tokumitsu, Y., Tomochika, S., Nakagami, Y., Takahashi, H., Nagano, H."Risk factors for infectious complications after gastrectomy in older patients". Experimental and Therapeutic Medicine 28, no. 2 (2024): 319. https://doi.org/10.3892/etm.2024.12608
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