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Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report

  • Authors:
    • Zhijian Xu
    • Song Yang
    • Qi Tu
    • Peiyue Han
    • Lixia Wang
    • Lude Wang
    • Minfeng Tong
    • Huahui Chen
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang 321000, P.R. China, Department of Neurosurgery, Jiaozhou Branch, East Hospital Affiliated to Tongji University, Qingdao, Shandong 266300, P.R. China, Department of Pathology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang 321000, P.R. China, Central Laboratory, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang 321000, P.R. China
    Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 327
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    Published online on: June 19, 2024
       https://doi.org/10.3892/etm.2024.12616
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Abstract

Extra‑adrenal myelolipoma (EAM) is a rare benign tumor composed of mature adipose and hematopoietic tissues. Its etiology remains to be elucidated and there are few case reports describing the clinical features and treatment of EAMs in the central nervous system. The present study presented our experience and practice in the clinical management of a case of EAM in the right frontal region. A 56‑year‑old woman was found to have a space‑occupying right frontal lesion on computed tomography (CT) of the head. Unenhanced magnetic resonance imaging (MRI) showed a lesion of ~1.5x1.2 cm. Enhanced whole abdominal CT showed a right presacral mass, 2.0 cm in diameter, with clear margins. The postoperative histopathological findings showed mainly mature adipose tissue mixed with extramedullary hematopoietic components. This confirmed the diagnosis of a (bone) marrow lipoma. Myelolipoma of the central nervous system is extremely rare. to the best of the authors' knowledge, only two cases of intracranial myelolipoma have been reported, and the present study introduced the first case in a Chinese patient reported in English. However, when CT shows high density and MRI shows mixed density in the tumor area even without enhancement, the possibility of myelolipoma should be considered in the differential diagnosis.
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Copy and paste a formatted citation
Spandidos Publications style
Xu Z, Yang S, Tu Q, Han P, Wang L, Wang L, Tong M and Chen H: Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report. Exp Ther Med 28: 327, 2024.
APA
Xu, Z., Yang, S., Tu, Q., Han, P., Wang, L., Wang, L. ... Chen, H. (2024). Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report. Experimental and Therapeutic Medicine, 28, 327. https://doi.org/10.3892/etm.2024.12616
MLA
Xu, Z., Yang, S., Tu, Q., Han, P., Wang, L., Wang, L., Tong, M., Chen, H."Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report". Experimental and Therapeutic Medicine 28.2 (2024): 327.
Chicago
Xu, Z., Yang, S., Tu, Q., Han, P., Wang, L., Wang, L., Tong, M., Chen, H."Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report". Experimental and Therapeutic Medicine 28, no. 2 (2024): 327. https://doi.org/10.3892/etm.2024.12616
Copy and paste a formatted citation
x
Spandidos Publications style
Xu Z, Yang S, Tu Q, Han P, Wang L, Wang L, Tong M and Chen H: Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report. Exp Ther Med 28: 327, 2024.
APA
Xu, Z., Yang, S., Tu, Q., Han, P., Wang, L., Wang, L. ... Chen, H. (2024). Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report. Experimental and Therapeutic Medicine, 28, 327. https://doi.org/10.3892/etm.2024.12616
MLA
Xu, Z., Yang, S., Tu, Q., Han, P., Wang, L., Wang, L., Tong, M., Chen, H."Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report". Experimental and Therapeutic Medicine 28.2 (2024): 327.
Chicago
Xu, Z., Yang, S., Tu, Q., Han, P., Wang, L., Wang, L., Tong, M., Chen, H."Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report". Experimental and Therapeutic Medicine 28, no. 2 (2024): 327. https://doi.org/10.3892/etm.2024.12616
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