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Case Report Open Access

Rare features of giant cell tumors of the bone: A case report

  • Authors:
    • Chao Wang
    • Ying Guo
    • Lu Wang
    • Zunzhen Nie
    • Jin Zhu
    • Qingguo Yan
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, School of Medicine, Northwest University, Xi'an, Shaanxi 710069, P.R. China, Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi 710000, P.R. China, Department of Pathology, Xi'an Daxing Hospital, Xi'an, Shaanxi 710003, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 409
    |
    Published online on: August 28, 2024
       https://doi.org/10.3892/etm.2024.12698
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Abstract

Giant cell tumors of the bone are local invasive diseases that are mainly composed of neoplastic monocytes and nonneoplastic multinucleated giant cells, mostly in the long bones of patients with mature bones. A specific H3F3A mutation is the key to its diagnosis. The present paper reports a case of giant cell tumor of the bone (GCTB) characterized by diffuse cholesterol crystals with few multinucleated giant cells. Imaging examination combined with immunohistochemical H3.3 G34W positivity was used to diagnose the patient with GCTB. Understanding the unique histological morphology of this patient will help doctors correctly diagnose giant cell tumors of bone and avoid misdiagnosis.
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Copy and paste a formatted citation
Spandidos Publications style
Wang C, Guo Y, Wang L, Nie Z, Zhu J and Yan Q: Rare features of giant cell tumors of the bone: A case report. Exp Ther Med 28: 409, 2024.
APA
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., & Yan, Q. (2024). Rare features of giant cell tumors of the bone: A case report. Experimental and Therapeutic Medicine, 28, 409. https://doi.org/10.3892/etm.2024.12698
MLA
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., Yan, Q."Rare features of giant cell tumors of the bone: A case report". Experimental and Therapeutic Medicine 28.5 (2024): 409.
Chicago
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., Yan, Q."Rare features of giant cell tumors of the bone: A case report". Experimental and Therapeutic Medicine 28, no. 5 (2024): 409. https://doi.org/10.3892/etm.2024.12698
Copy and paste a formatted citation
x
Spandidos Publications style
Wang C, Guo Y, Wang L, Nie Z, Zhu J and Yan Q: Rare features of giant cell tumors of the bone: A case report. Exp Ther Med 28: 409, 2024.
APA
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., & Yan, Q. (2024). Rare features of giant cell tumors of the bone: A case report. Experimental and Therapeutic Medicine, 28, 409. https://doi.org/10.3892/etm.2024.12698
MLA
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., Yan, Q."Rare features of giant cell tumors of the bone: A case report". Experimental and Therapeutic Medicine 28.5 (2024): 409.
Chicago
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., Yan, Q."Rare features of giant cell tumors of the bone: A case report". Experimental and Therapeutic Medicine 28, no. 5 (2024): 409. https://doi.org/10.3892/etm.2024.12698
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