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Case Report Open Access

Imatinib‑induced gynecomastia: A case report

  • Authors:
    • Xiao-Lan Li
    • Min Li
    • Sheng-Ke Tu
    • Hong-Jie Fan
    • Zi-Wei Shi
    • Ling-Zhi Wang
    • Juan Tian
    • Kui Song
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, The First Affiliated Hospital of Jishou University, Jishou, Hunan 416000, P.R. China, Department of Pharmacy, The First Affiliated Hospital of Jishou University, Jishou, Hunan 416000, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 425
    |
    Published online on: September 11, 2024
       https://doi.org/10.3892/etm.2024.12714
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Abstract

Chronic myeloid leukemia is a myeloproliferative neoplasm characterized by the unregulated and abnormal proliferation of both mature and immature granulocytes, which results in the proliferation of peripheral blood leukocytes. Imatinib, a tyrosine kinase inhibitor, is the first‑line treatment for patients diagnosed with chronic myeloid leukemia. However, despite its favorable safety profile, imatinib use is associated with a number of side effects. Gynecomastia is a rare adverse effect of imatinib treatment and may be associated with an imbalance in sex hormones. The present study reports the case of a patient with chronic myeloid leukemia diagnosed with gynecomastia after imatinib treatment. The aim of the present report was to highlight to clinicians this adverse reaction to imatinib treatment and investigate a treatment strategy with fewer side effects.
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Copy and paste a formatted citation
Spandidos Publications style
Li X, Li M, Tu S, Fan H, Shi Z, Wang L, Tian J and Song K: Imatinib‑induced gynecomastia: A case report. Exp Ther Med 28: 425, 2024.
APA
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L. ... Song, K. (2024). Imatinib‑induced gynecomastia: A case report. Experimental and Therapeutic Medicine, 28, 425. https://doi.org/10.3892/etm.2024.12714
MLA
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L., Tian, J., Song, K."Imatinib‑induced gynecomastia: A case report". Experimental and Therapeutic Medicine 28.5 (2024): 425.
Chicago
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L., Tian, J., Song, K."Imatinib‑induced gynecomastia: A case report". Experimental and Therapeutic Medicine 28, no. 5 (2024): 425. https://doi.org/10.3892/etm.2024.12714
Copy and paste a formatted citation
x
Spandidos Publications style
Li X, Li M, Tu S, Fan H, Shi Z, Wang L, Tian J and Song K: Imatinib‑induced gynecomastia: A case report. Exp Ther Med 28: 425, 2024.
APA
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L. ... Song, K. (2024). Imatinib‑induced gynecomastia: A case report. Experimental and Therapeutic Medicine, 28, 425. https://doi.org/10.3892/etm.2024.12714
MLA
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L., Tian, J., Song, K."Imatinib‑induced gynecomastia: A case report". Experimental and Therapeutic Medicine 28.5 (2024): 425.
Chicago
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L., Tian, J., Song, K."Imatinib‑induced gynecomastia: A case report". Experimental and Therapeutic Medicine 28, no. 5 (2024): 425. https://doi.org/10.3892/etm.2024.12714
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