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Review Open Access

Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review)

  • Authors:
    • Vasiliki Epameinondas Georgakopoulou
    • Chrysoula Taskou
    • Demetrios A. Spandidos
    • Athina Diamanti
  • View Affiliations / Copyright

    Affiliations: Department of Pathophysiology, Laiko General Hospital, Medical School of National and Kapodistrian University of Athens, 11527 Athens, Greece, Department of Midwifery, Faculty of Health and Caring Sciences, University of West Attica, 12243 Athens, Greece, Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece
    Copyright: © Georgakopoulou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 454
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    Published online on: October 11, 2024
       https://doi.org/10.3892/etm.2024.12744
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Abstract

Asthma, a common chronic respiratory condition, poses unique challenges in pregnancy, impacting both maternal and fetal health. Of note, 8‑13% of pregnant women suffer from asthma, a condition that can worsen, stabilize, or improve during pregnancy. These fluctuations necessitate a nuanced management strategy to ensure the health of both the mother and fetus. Adverse outcomes, such as preeclampsia, gestational diabetes and increased cesarean delivery rates are associated with poorly controlled asthma. From a fetal perspective, the risks include preterm birth and a low birth weight. Physiological changes in pregnancy, such as an increased tidal volume and altered drug metabolism due to increased blood volume, complicate the management of asthma. The safety of asthma medications during pregnancy remains a significant concern, with ongoing research into their teratogenic effects. Recent advancements in treatment include the development of biologics and the increased use of personalized medicine, integrating pharmacogenomics and immunological profiling to tailor treatments to individual needs. Digital health tools have also emerged, enabling improved patient monitoring and management. The present review highlights the complex interplay between asthma management and pregnancy outcomes, advocating for comprehensive care approaches that consider the dynamic physiological changes during pregnancy. It underscores the need for ongoing research into the safety of medication and innovative therapeutic strategies to improve health outcomes for pregnant women with asthma and their babies.
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Copy and paste a formatted citation
Spandidos Publications style
Georgakopoulou VE, Taskou C, Spandidos DA and Diamanti A: Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review). Exp Ther Med 28: 454, 2024.
APA
Georgakopoulou, V.E., Taskou, C., Spandidos, D.A., & Diamanti, A. (2024). Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review). Experimental and Therapeutic Medicine, 28, 454. https://doi.org/10.3892/etm.2024.12744
MLA
Georgakopoulou, V. E., Taskou, C., Spandidos, D. A., Diamanti, A."Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review)". Experimental and Therapeutic Medicine 28.6 (2024): 454.
Chicago
Georgakopoulou, V. E., Taskou, C., Spandidos, D. A., Diamanti, A."Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review)". Experimental and Therapeutic Medicine 28, no. 6 (2024): 454. https://doi.org/10.3892/etm.2024.12744
Copy and paste a formatted citation
x
Spandidos Publications style
Georgakopoulou VE, Taskou C, Spandidos DA and Diamanti A: Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review). Exp Ther Med 28: 454, 2024.
APA
Georgakopoulou, V.E., Taskou, C., Spandidos, D.A., & Diamanti, A. (2024). Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review). Experimental and Therapeutic Medicine, 28, 454. https://doi.org/10.3892/etm.2024.12744
MLA
Georgakopoulou, V. E., Taskou, C., Spandidos, D. A., Diamanti, A."Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review)". Experimental and Therapeutic Medicine 28.6 (2024): 454.
Chicago
Georgakopoulou, V. E., Taskou, C., Spandidos, D. A., Diamanti, A."Complex interplays: Asthma management and maternal‑fetal outcomes in pregnancy (Review)". Experimental and Therapeutic Medicine 28, no. 6 (2024): 454. https://doi.org/10.3892/etm.2024.12744
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