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Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study

  • Authors:
    • Guoqing Zhang
    • Danna Ma
    • Bo Li
    • Li Bao
    • Hongyan Luo
    • Shilu Cao
    • Yali Zheng
  • View Affiliations / Copyright

    Affiliations: The Third Clinical Medical College, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750000, P.R. China, Department of Nephrology, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia Hui Autonomous Region 750000, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 7
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    Published online on: October 29, 2024
       https://doi.org/10.3892/etm.2024.12757
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Abstract

The coronavirus disease 2019 (COVID‑19) is spreading continuously worldwide. Maintenance hemodialysis (MHD) patients are a particular group at higher risk of contracting COVID‑19. The aim of the present study was to investigate the various risk factors that contribute to the occurrence of co‑infection with COVID‑19 among patients with MHD. A retrospective analysis was conducted on 171 patients with MHD. The characteristics and outcomes were examined among patients with MHD who were infected with COVID‑19 and those who were not. Moreover, risk factors associated with survival or mortality among the COVID‑19‑infected patients with MHD were analyzed. The results of the present study revealed that the mean level of 25‑hydroxyvitamin D [25(OH)D] in patients with MHD was 22.3±11.28 ng/ml. However, there was no significant difference in the levels of 25(OH)D between patients with MHD with and without COVID‑19. Logistic regression analysis revealed that decreased levels of intact parathyroid hormone (iPTH) and increased levels of serum ferritin were associated with an increased risk of COVID‑19 in these patients. Additionally, the levels of 25(OH)D and albumin were decreased in the deceased patients. Similarly, logistic regression analysis was performed to identify risk factors for mortality in patients with MHD with COVID‑19, which revealed that decreased levels of 25(OH)D were associated with an increased risk of mortality in these patients. The results of the present study indicated that iPTH and serum ferritin levels could potentially increase the risk of COVID‑19 among patients with MHD. Additionally, 25(OH)D levels may influence the mortality rate among patients with MHD who have been infected with COVID‑19.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang G, Ma D, Li B, Bao L, Luo H, Cao S and Zheng Y: Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study. Exp Ther Med 29: 7, 2025.
APA
Zhang, G., Ma, D., Li, B., Bao, L., Luo, H., Cao, S., & Zheng, Y. (2025). Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study. Experimental and Therapeutic Medicine, 29, 7. https://doi.org/10.3892/etm.2024.12757
MLA
Zhang, G., Ma, D., Li, B., Bao, L., Luo, H., Cao, S., Zheng, Y."Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study". Experimental and Therapeutic Medicine 29.1 (2025): 7.
Chicago
Zhang, G., Ma, D., Li, B., Bao, L., Luo, H., Cao, S., Zheng, Y."Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study". Experimental and Therapeutic Medicine 29, no. 1 (2025): 7. https://doi.org/10.3892/etm.2024.12757
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang G, Ma D, Li B, Bao L, Luo H, Cao S and Zheng Y: Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study. Exp Ther Med 29: 7, 2025.
APA
Zhang, G., Ma, D., Li, B., Bao, L., Luo, H., Cao, S., & Zheng, Y. (2025). Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study. Experimental and Therapeutic Medicine, 29, 7. https://doi.org/10.3892/etm.2024.12757
MLA
Zhang, G., Ma, D., Li, B., Bao, L., Luo, H., Cao, S., Zheng, Y."Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study". Experimental and Therapeutic Medicine 29.1 (2025): 7.
Chicago
Zhang, G., Ma, D., Li, B., Bao, L., Luo, H., Cao, S., Zheng, Y."Clinical characteristics of patients with maintenance hemodialysis affected by COVID‑19: A single‑center retrospective study". Experimental and Therapeutic Medicine 29, no. 1 (2025): 7. https://doi.org/10.3892/etm.2024.12757
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