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Case Report Open Access

Retroperitoneal ovarian venous hemangioma: A case report

  • Authors:
    • Jie Tian
    • Hong Hu
    • Siyi Chen
    • Junping Li
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Postgraduate Union Training Base of Xiangyang No. 1 People's Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, Hubei 441000, P.R. China, Department of Radiology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China
    Copyright: © Tian et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 153
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    Published online on: April 8, 2026
       https://doi.org/10.3892/etm.2026.13148
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Abstract

Retroperitoneal venous hemangioma is a rare vascular malformation. The present study reports a unique case of a 68‑year‑old female with a retroperitoneal ovarian venous hemangioma that was surgically resected. Computed tomography and magnetic resonance imaging showed a retroperitoneal mass anterior to the left kidney. Enhanced imaging revealed a close relationship between the mass and surrounding vessels, suggesting a retroperitoneal vascular neoplasm. Histopathological examination of the tissue after complete surgical resection confirmed the diagnosis of a retroperitoneal ovarian venous hemangioma. This case provides crucial insights for clinicians to enhance their understanding of ovarian venous hemangioma through the integration of multimodal imaging characteristics and pathological evidence, thereby contributing to the reduction of misdiagnosis in clinical practice.
View Figures

Figure 1

CT images of the retroperitoneal mass.
(A) Plain scan. (B) Arterial phase. (C) Venous phase. (D) Delayed
phase. (E) CT enhanced coronal image shows the range of the mass
and its relationship with adjacent structures (red arrow). (F) CT
enhanced coronal image. (G) Sagittal maximum intensity projection
image showing the association between the mass (red arrow) and the
ovarian vein (yellow arrow). (H) 3D reconstructed image shows the
mass (red arrow) connecting the left ovarian vein (yellow arrow) at
its upper and lower poles, joining the left renal vein.

Figure 2

MRI of the retroperitoneal mass. (A)
MRI T2 transverse. (B) MRI coronal images show the signal
characteristics of the mass (red arrow) and adjacent structures.
(C) MRI T1 transverse image. (D) MRI enhanced coronal image shows
significant non-uniform enhancement. (E) Diffusion-weighted imaging
demonstrated a mild high signal. (F) Apparent Diffusion
Coefficient: Mild low signal, indicating mild diffusion
restriction. (G) Out-of-phase: No signal drop vs. in-phase. (H)
In-phase: Anatomical reference indicates no fat component.

Figure 3

Intraoperative and pathological
features of the retroperitoneal mass. (A) Intraoperative gross
anatomy shows the ovarian vein (yellow arrow) connecting the mass
(red arrow) and joining the left renal vein. (B) Hematoxylin and
eosin staining revealed thick-walled vascular channels and
disorganized smooth muscle bundles. (C) Immunohistochemical
staining shows positive CD31 staining [(SH28.1) scale bar=50 µm;
magnification, x200]. (D) Immunohistochemical staining shows
positive CD31 and CD34 staining [(SH28.1) scale bar=50 µm;
magnification, x200].

Figure 4

Pathological immunohistochemical
images. Immunohistochemical staining for (A) Vimentin, (B)
ETS-related gene), (C) Fli-1 (Friend leukemia virus integration
site 1), (D) α-inhibin, (E) D2-40 (podoplanin), (F) SMA (smooth
muscle actin), (G) STAT6, (H) PCK (pan-cytokeratin), (I) Syn
(synaptophysin), (J) CgA (chromogranin A), (K) GATA binding protein
3), (L) Melan-A, (M) Desmin and (N) Ki-67 (magnification, x200).
(O) S-100 (scale bar=50 µm; magnification, x40)
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Copy and paste a formatted citation
Spandidos Publications style
Tian J, Hu H, Chen S and Li J: Retroperitoneal ovarian venous hemangioma: A case report. Exp Ther Med 31: 153, 2026.
APA
Tian, J., Hu, H., Chen, S., & Li, J. (2026). Retroperitoneal ovarian venous hemangioma: A case report. Experimental and Therapeutic Medicine, 31, 153. https://doi.org/10.3892/etm.2026.13148
MLA
Tian, J., Hu, H., Chen, S., Li, J."Retroperitoneal ovarian venous hemangioma: A case report". Experimental and Therapeutic Medicine 31.6 (2026): 153.
Chicago
Tian, J., Hu, H., Chen, S., Li, J."Retroperitoneal ovarian venous hemangioma: A case report". Experimental and Therapeutic Medicine 31, no. 6 (2026): 153. https://doi.org/10.3892/etm.2026.13148
Copy and paste a formatted citation
x
Spandidos Publications style
Tian J, Hu H, Chen S and Li J: Retroperitoneal ovarian venous hemangioma: A case report. Exp Ther Med 31: 153, 2026.
APA
Tian, J., Hu, H., Chen, S., & Li, J. (2026). Retroperitoneal ovarian venous hemangioma: A case report. Experimental and Therapeutic Medicine, 31, 153. https://doi.org/10.3892/etm.2026.13148
MLA
Tian, J., Hu, H., Chen, S., Li, J."Retroperitoneal ovarian venous hemangioma: A case report". Experimental and Therapeutic Medicine 31.6 (2026): 153.
Chicago
Tian, J., Hu, H., Chen, S., Li, J."Retroperitoneal ovarian venous hemangioma: A case report". Experimental and Therapeutic Medicine 31, no. 6 (2026): 153. https://doi.org/10.3892/etm.2026.13148
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