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Factors affecting central sensitization inventory score before surgery for distal radius fractures

  • Authors:
    • Shoichiro Ishii
    • Kiyohito Naito
    • Norizumi Imazu
    • Takamaru Suzuki
    • Kenjiro Kawamura
    • So Kawakita
    • Tatsuki Itoh
    • Muneaki Ishijima
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics, Juntendo University Faculty of Medicine, Tokyo 113‑8421, Japan
    Copyright: © Ishii et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 162
    |
    Published online on: April 9, 2026
       https://doi.org/10.3892/etm.2026.13157
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Abstract

Volar locking plate fixation enables early postoperative return to daily activities. However, from the patient's perspective, undergoing surgery can pose substantial challenges. In particular, the perioperative period is considered a time of high psychological stress. The central sensitization inventory (CSI) score is an assessment tool for psychosocial factors in pain. In the present study, the utility of CSI scores for assessing the psychosocial factors influencing patients' status before surgery for distal radius fracture (DRF) were evaluated. This study included 22 patients who underwent volar locking plate fixation of DRF. Before surgery, data on sex, side of injury, fracture type, age, interval (in days) from injury to evaluation, numerical rating scale (NRS), Quick Disabilities of the Arm, Shoulder and Hand (Q‑DASH) score and CSI score were collected. We analyzed the relationship between each evaluation item and CSI score. There were no significant associations between CSI score and sex (P=0.389), side of injury (P=0.774), fracture type (P=0.063), interval from injury to evaluation (P=0.529, r=‑0.142) and Q‑DASH score (P=0.385, r=0.195). On the other hand, significant associations between CSI score and age (P=0.049, r=0.424) and NRS (P=0.003, r=0.607) were found. CSI scores were significantly associated with age and NRS before volar locking plate fixation for DRF. Mental stress management and nociceptive pain relief for elderly patients may be useful in preoperative patient care.
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1 

Prajapati P, Kumar A, Chaudary Mangrulkar S, Arya M and Kushwaha S: A comprehensive review of essential aspects of molecular pathophysiological mechanisms with emerging interventions for sarcopenia in older people. Curr Mol Pharmacol. 17(e080323214478)2024.PubMed/NCBI View Article : Google Scholar

2 

Ando J, Takahashi T, Ae R, Ajiki T, Matsumura T, Sasao W, Abe M and Takeshita K: Epidemiology of distal radius fracture: A regional population-based study in Japan. BMC Musculoskelet Disord. 24(478)2023.PubMed/NCBI View Article : Google Scholar

3 

Muzzammil M, Bhura S, Hussain AS, Bashir S, Muhammad SD, Kumar M, Qadir A, Jahanzeb S and Shah SGM: Undiagnosed vertebral fragility fractures in patients with distal radius fragility fractures: An opportunity for prevention of morbimortality in oeteoporotic patients in developing countries. Osteoporos Int. 35:1773–1778. 2024.PubMed/NCBI View Article : Google Scholar

4 

Prevention and management of osteoporosis. World Health Organ Tech Rep Ser. 921:1–164. 2003.PubMed/NCBI

5 

Greig D and Silva M: Management of distal radius fractures in adolescent patients. J Pediatr Orthop. 41 (Suppl 1):S1–S5. 2021.PubMed/NCBI View Article : Google Scholar

6 

Lv G, Zhao D, Li G, Qi M, Dong X and Li P: When experiencing a surgery: Gastrointestinal cancer patients' longitudinal trajectories in psychological stress and their association with quality of recovery. Asia Pac J Oncol Nurs. 9(100064)2022.PubMed/NCBI View Article : Google Scholar

7 

Jung KW, Park JH, Ahn JW and Park KB: Surgery-related anxiety on geriatric patients undergoing total knee arthroplasty: A retrospective observational study. BMC Musculoskelet Disord. 24(161)2023.PubMed/NCBI View Article : Google Scholar

8 

Suzuki K, Haruyama Y, Kobashi G, Sairenchi T, Uchiyama K, Yamaguchi S and Hirata K: Central sensitization in neurological, psychiatric, and pain disorders: A multicenter case-controlled study. Pain Res Manag. 2021(6656917)2021.PubMed/NCBI View Article : Google Scholar

9 

Salbego RS, Conti PCR, Soares FFC, Ferreira DMAO, Herreira-Ferreira M, de Lima-Netto BA, Costa YM and Bonjardim LR: Central sensitization inventory is associated with psychological functioning but not with psychophysical assessment of pain amplification. Eur J Pain. 29(e4713)2025.PubMed/NCBI View Article : Google Scholar

10 

Neblett R, Cohen H, Choi Y, Hartzell MM, Williams M, Mayer TG and Gatchel RJ: The central sensitization inventory (CSI): Establishing clinically-significant values for identifying central sensitivity syndromes in an outpatient chronic pain sample. J Pain. 14:438–445. 2013.PubMed/NCBI View Article : Google Scholar

11 

Hawker GA, Mian S, Kendzerska T and French M: Measures of adults pain: Visual analog scale for pain (VAS Pain), Numeric rating scale for pain (NRS Pain), McGill pain questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic pain grade scale (CPGS), Short form-36 bodily pain scale (SF-36 BPS), and measure of intermittent and constant osteoarthritis pain (ICOAP). Arthritis Care Res (Hoboken). 63 (Suppl 11):S240–S252. 2011.PubMed/NCBI View Article : Google Scholar

12 

Beaton DE, Wright JG and Katz JN: Upper Extremity Collaborative Group. Development of the QuickDASH: Comparison of three item-reduction approaches. J Bone Joint Surg Am. 87:1038–1046. 2005.PubMed/NCBI View Article : Google Scholar

13 

Storesund A, Krukhaug Y, Olsen MV, Rygh LJ, Nilsen RM and Norekvål TM: Females report higher postoperative pain scores than males after ankle surgery. Scand J Pain. 12:85–93. 2016.PubMed/NCBI View Article : Google Scholar

14 

Iitsuka T, Kurumadani H, Inagaki Y and Ota H: Recovery in the symmetry of hand use after distal radius fracture. Hand Ther. 30:72–81. 2025.PubMed/NCBI View Article : Google Scholar

15 

Yulian K and Christian SA: Intra-articular versus extra-articular distal radius fractures: Management strategies and outcomes. Int J Res Rev. 12:311–319. 2025.

16 

Souer JS, Ring D, Jupiter JB, Matschke S, Audige L and Marent-Huber M: AOCID Prospective ORIF Distal Radius Study Group. Comparison of AO type-B and type-C colar shearing fractures of the distal part of the radius. J Bone Joint Surg Am. 91:2605–2611. 2009.

17 

Wilson K, von der Heyde R, Sparks M, Hammerschmidt K, Pleimann D, Ranz E, Rector J and Sniezak D: The impact of demographic factors and comorbidities on distal radius fracture outcomes. Hand (N Y). 9:80–86. 2014.PubMed/NCBI View Article : Google Scholar

18 

Kawamura K, Naito K, Suzuki T, Yamamoto Y, Kawakita S, Imazu N and Ishijima M: Factors that interfere with immediate return to activity following volar locking plate fixation for distal radius fractures. Med Int (Lond). 4(65)2024.PubMed/NCBI View Article : Google Scholar

19 

Testa G, Panvini FMC, Vaccalluzzo MS, Cristaudo AG, Sapienza M and Pavone V: Surgical treatment of periarticular distal radius fracture in elderly: A systematic review. Medicina (Kaunas). 60(1671)2024.PubMed/NCBI View Article : Google Scholar

20 

Bian Z, Xu R, Shang B, Lv F, Sun W, Li Q, Gong Y and Luo C: Associations between anxiety, depression, and personal mastery in community-dwelling older adults: A network-based analysis. BMC Psychiatry. 24(192)2024.PubMed/NCBI View Article : Google Scholar

21 

Kovačević I, Pavić J, Filipović B, Ozimec Vulinec Š, Ilić B and Petek D: Integrated approach to chronic pain- the role of psychosocial factors and multidisciplinary treatment: A narrative review. Int J Environ Res Public Health. 21(1135)2024.PubMed/NCBI View Article : Google Scholar

22 

Akeda K, Takegami N, Yamada J, Fujiwara T, Nishimura A and Sudo A: Central sensitization in chronic low back pain: A population-based study of a Japanese mountain village. J Pain Res. 14:1271–1280. 2021.PubMed/NCBI View Article : Google Scholar

23 

Ohashi Y, Fukushima K, Inoue G, Uchida K, Koyama T, Tsuchiya M, Uchiyama K, Takahira N and Takaso M: Central sensitization inventory scores correlate with pain at rest in patients with hip osteoarthritis: A retrospective study. BMC Musculoskelet Disord. 21(595)2020.PubMed/NCBI View Article : Google Scholar

24 

Riley RD, Snell KIE, Ensor J, Burke DL, Harrell FE Jr, Moons KGM and Collons GS: Minimum sample size for developing a multivariable prediction model: Part I- Continuous outcomes. Stat Med. 38:1262–1275. 2019.PubMed/NCBI View Article : Google Scholar

25 

Mayer TG, Neblett R, Cohen H, Howard KJ, Choi YH, Williams MJ, Perez Y and Gatchel RJ: The development and psychometric validation of the central sensitization inventory. Pain Pract. 12:276–285. 2012.PubMed/NCBI View Article : Google Scholar

26 

Neblett R, Hartzell MM, Mayer TG, Cohen H and Gatchel RJ: Establishing clinically relevant severity levels for the central sensitization inventory. Pain Pract. 17:166–175. 2017.PubMed/NCBI View Article : Google Scholar

27 

Pickering ME, Javier RM, Malochet S, Pickering G and Desmeules J: Osteoporosis treatment and pain relief: A scoping review. Eur J Pain. 28:3–20. 2024.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Ishii S, Naito K, Imazu N, Suzuki T, Kawamura K, Kawakita S, Itoh T and Ishijima M: Factors affecting central sensitization inventory score before surgery for distal radius fractures. Exp Ther Med 31: 162, 2026.
APA
Ishii, S., Naito, K., Imazu, N., Suzuki, T., Kawamura, K., Kawakita, S. ... Ishijima, M. (2026). Factors affecting central sensitization inventory score before surgery for distal radius fractures. Experimental and Therapeutic Medicine, 31, 162. https://doi.org/10.3892/etm.2026.13157
MLA
Ishii, S., Naito, K., Imazu, N., Suzuki, T., Kawamura, K., Kawakita, S., Itoh, T., Ishijima, M."Factors affecting central sensitization inventory score before surgery for distal radius fractures". Experimental and Therapeutic Medicine 31.6 (2026): 162.
Chicago
Ishii, S., Naito, K., Imazu, N., Suzuki, T., Kawamura, K., Kawakita, S., Itoh, T., Ishijima, M."Factors affecting central sensitization inventory score before surgery for distal radius fractures". Experimental and Therapeutic Medicine 31, no. 6 (2026): 162. https://doi.org/10.3892/etm.2026.13157
Copy and paste a formatted citation
x
Spandidos Publications style
Ishii S, Naito K, Imazu N, Suzuki T, Kawamura K, Kawakita S, Itoh T and Ishijima M: Factors affecting central sensitization inventory score before surgery for distal radius fractures. Exp Ther Med 31: 162, 2026.
APA
Ishii, S., Naito, K., Imazu, N., Suzuki, T., Kawamura, K., Kawakita, S. ... Ishijima, M. (2026). Factors affecting central sensitization inventory score before surgery for distal radius fractures. Experimental and Therapeutic Medicine, 31, 162. https://doi.org/10.3892/etm.2026.13157
MLA
Ishii, S., Naito, K., Imazu, N., Suzuki, T., Kawamura, K., Kawakita, S., Itoh, T., Ishijima, M."Factors affecting central sensitization inventory score before surgery for distal radius fractures". Experimental and Therapeutic Medicine 31.6 (2026): 162.
Chicago
Ishii, S., Naito, K., Imazu, N., Suzuki, T., Kawamura, K., Kawakita, S., Itoh, T., Ishijima, M."Factors affecting central sensitization inventory score before surgery for distal radius fractures". Experimental and Therapeutic Medicine 31, no. 6 (2026): 162. https://doi.org/10.3892/etm.2026.13157
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