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Case Report Open Access

Postmenopausal complete hydatidiform mole: A case report

  • Authors:
    • Emre Uysal
  • View Affiliations / Copyright

    Affiliations: Department of Gynecology and Obstetrics, Eregli State Hospital, Eregli, Konya 42310, Turkiye
    Copyright: © Uysal et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 170
    |
    Published online on: April 20, 2026
       https://doi.org/10.3892/etm.2026.13165
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Abstract

Complete hydatidiform mole (CHM) cases occurring in the postmenopausal period are quite rare and may be delayed in diagnosis. In the present study, the case reported is of a 55‑year‑old postmenopausal woman (menopausal for 5 years) who presented with painless postmenopausal bleeding in March 2025, ongoing for ~1 month and was diagnosed with CHM. Transvaginal ultrasonography showed endometrial thickness of 28‑mm and serum β‑human chorionic gonadotropin (β‑hCG) level of 187,240 mIU/ml. After ultrasound‑guided curettage, the diagnosis of CHM was confirmed in histopathological examination. Since the patient was postmenopausal, laparoscopic hysterectomy and bilateral salpingo‑oophorectomy were performed. Postoperative follow‑up was performed in accordance with International Federation of Gynecology and Obstetrics (FIGO) guidelines; the protocol used (weekly β‑hCG until negative, then monthly for 6 months) is fully consistent with the 2025 FIGO update. By December 2025, the patient had successfully finished the suggested follow‑up regimen and was still in total remission with no signs of recurrence. In patients with abnormal uterine bleeding and high β‑hCG levels in the postmenopausal period, gestational trophoblastic diseases should be considered in the differential diagnosis. Malignant complications can be prevented with early diagnosis and treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Uysal E: Postmenopausal complete hydatidiform mole: A case report. Exp Ther Med 31: 170, 2026.
APA
Uysal, E. (2026). Postmenopausal complete hydatidiform mole: A case report. Experimental and Therapeutic Medicine, 31, 170. https://doi.org/10.3892/etm.2026.13165
MLA
Uysal, E."Postmenopausal complete hydatidiform mole: A case report". Experimental and Therapeutic Medicine 31.6 (2026): 170.
Chicago
Uysal, E."Postmenopausal complete hydatidiform mole: A case report". Experimental and Therapeutic Medicine 31, no. 6 (2026): 170. https://doi.org/10.3892/etm.2026.13165
Copy and paste a formatted citation
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Spandidos Publications style
Uysal E: Postmenopausal complete hydatidiform mole: A case report. Exp Ther Med 31: 170, 2026.
APA
Uysal, E. (2026). Postmenopausal complete hydatidiform mole: A case report. Experimental and Therapeutic Medicine, 31, 170. https://doi.org/10.3892/etm.2026.13165
MLA
Uysal, E."Postmenopausal complete hydatidiform mole: A case report". Experimental and Therapeutic Medicine 31.6 (2026): 170.
Chicago
Uysal, E."Postmenopausal complete hydatidiform mole: A case report". Experimental and Therapeutic Medicine 31, no. 6 (2026): 170. https://doi.org/10.3892/etm.2026.13165
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