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Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress

  • Authors:
    • Ágnes Szepesi
    • Lilla Sípos
    • Réka Szőllősi
    • Péter Pálfi
    • László Bakacsy
  • View Affiliations / Copyright

    Affiliations: Department of Plant Biology, Institute of Biology, Faculty of Science and Informatics, University of Szeged, H‑6726 Szeged, Hungary
    Copyright: © Szepesi et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 6
    |
    Published online on: November 26, 2024
       https://doi.org/10.3892/ijfn.2024.40
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Abstract

Tomato is one of the primary agricultural plants, grown in various areas affected by salt stress. Protein translation is a crucial process in the stress tolerance of crop plants. There is evidence to indicate that hypusination, which is a polyamine‑dependent metabolic post‑translational modification of eukaryotic translation factor 5A, may play a crucial role in tolerance to salt stress. In the present study, in order to clarify the importance of the first step of hypusination, the deoxyhypusine synthase (DHS) pharmacological inhibitor, GC7, was applied. A pot experiment was undertaken to examine the effects of the inhibition of DHS by GC7 on tomato (Solanum lycopersicum) flower and fruit parameters under conditions of salt stress. The results revealed that GC7 promoted the formation of more flowers and fruits in tomato plants subjected to salt stress, and effectively increased the bioactive lycopene content during conditions of salt stress. On the whole, the findings of the present study demonstrate that the modulation of hypusination may be a promising breeding target with which to enhance the tolerance of tomato plants to salt stress.
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Spandidos Publications style
Szepesi Á, Sípos L, Szőllősi R, Pálfi P and Bakacsy L: Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress. Int J Funct Nutr 5: 6, 2024.
APA
Szepesi, Á., Sípos, L., Szőllősi, R., Pálfi, P., & Bakacsy, L. (2024). Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress. International Journal of Functional Nutrition, 5, 6. https://doi.org/10.3892/ijfn.2024.40
MLA
Szepesi, Á., Sípos, L., Szőllősi, R., Pálfi, P., Bakacsy, L."Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress". International Journal of Functional Nutrition 5.1 (2024): 6.
Chicago
Szepesi, Á., Sípos, L., Szőllősi, R., Pálfi, P., Bakacsy, L."Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress". International Journal of Functional Nutrition 5, no. 1 (2024): 6. https://doi.org/10.3892/ijfn.2024.40
Copy and paste a formatted citation
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Spandidos Publications style
Szepesi Á, Sípos L, Szőllősi R, Pálfi P and Bakacsy L: Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress. Int J Funct Nutr 5: 6, 2024.
APA
Szepesi, Á., Sípos, L., Szőllősi, R., Pálfi, P., & Bakacsy, L. (2024). Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress. International Journal of Functional Nutrition, 5, 6. https://doi.org/10.3892/ijfn.2024.40
MLA
Szepesi, Á., Sípos, L., Szőllősi, R., Pálfi, P., Bakacsy, L."Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress". International Journal of Functional Nutrition 5.1 (2024): 6.
Chicago
Szepesi, Á., Sípos, L., Szőllősi, R., Pálfi, P., Bakacsy, L."Inhibition of deoxyhypusine synthase by GC7 induces the modification of fruit setting and polyamine catabolism in tomato plants exposed to salt stress". International Journal of Functional Nutrition 5, no. 1 (2024): 6. https://doi.org/10.3892/ijfn.2024.40
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