Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Functional Nutrition
Join Editorial Board Propose a Special Issue
Print ISSN: 2634-7989 Online ISSN: 2634-7237
Journal Cover
January-December 2026 Volume 7 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-December 2026 Volume 7 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (Eucheuma cottonii) flour substitution in cookies

  • Authors:
    • Yusny Dwi Astari Bolu
    • Fery Lusviana Widiany
    • Siti Wahyuningsih
  • View Affiliations / Copyright

    Affiliations: Bachelor of Nutrition Study Program, Faculty of Health Science, Universitas Respati Yogyakarta, Yogyakarta 55282, Indonesia, Dietician Profession Education Study Program, Faculty of Health Science, Universitas Respati Yogyakarta, Yogyakarta 55282, Indonesia
    Copyright: © Bolu et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 3
    |
    Published online on: April 6, 2026
       https://doi.org/10.3892/ijfn.2026.55
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:


Abstract

Seaweed (Eucheuma cottonii) is one of the Indonesian local foods. Seaweed contains high levels of dietary fiber, vitamin C and polyphenols, which are beneficial for patients with coronary heart disease. Seaweed can be made into flour and processed into cookies. The present study aimed to determine the effects of seaweed (Eucheuma cottonii) flour substitution on the dietary fiber, vitamin C and polyphenol content in cookies for patients with coronary heart disease. The present experimental study used three treatment groups with one control group. The present experimental study prepared three different variations of cookies and one cookie formulation used as the control, as follows: i) Cookies A (the control): The cookies were prepared from 100% wheat flour (without seaweed flour substitution); ii) cookies B were prepared from the combination of 80% wheat flour and 20% seaweed flour; iii) cookies C were prepared from the combination of 70% wheat flour and 30% seaweed flour; iv) and cookies D were prepared from the combination of 60% wheat flour and 40% seaweed flour. The dietary fiber, vitamin C and polyphenol contents were then obtained. The dietary fiber data were analyzed using the Kruskal‑Wallis test followed by the Bonferroni test as a post hoc test. The vitamin C and polyphenol data were analyzed using one‑way ANOVA followed by the Games‑Howell Test. There was a significant difference within the groups with various compositions of seaweed powder substitution in terms of the dietary fiber (P=0.003), vitamin C (P<0.001), and polyphenol (P<0.001) contents. The highest content of dietary fiber, vitamin C and polyphenol was found in cookies D. On the whole, the present study demonstrates that seaweed (Eucheuma cottonii) flour substitution affects the dietary fiber, vitamin C and polyphenol content in cookies, and this is beneficial for patients with coronary heart disease.
View Figures
View References

1 

Di Cesare M, Perel P, Taylor S, Kabudula C, Bixby H, Gaziano TA, McGhie DV, Mwangi J, Pervan B, Narula J, et al: The heart of the world. Glob Heart. 19(11)2024.PubMed/NCBI View Article : Google Scholar

2 

Muharram FR, Multazam CECZ, Mustofa A, Socha W, Andrianto Martini S, Aminde L and Yi-Li C: The 30 years of shifting in the indonesian cardiovascular burden-analysis of the global burden of disease study. J Epidemiol Glob Health. 14:193–212. 2024.PubMed/NCBI View Article : Google Scholar

3 

Wu Y, Qian Y, Pan Y, Li P, Yang J, Ye X and Xu G: Association between dietary fiber intake and risk of coronary heart disease: A meta-analysis. Clin Nutr. 34:603–611. 2015.PubMed/NCBI View Article : Google Scholar

4 

Zhang L, Chen Y, Yang Q, Guo J, Zhou S, Zhong T, Xiao Y, Yu X, Feng K, Peng Y, et al: The impact of dietary fiber on cardiovascular diseases: A scoping review. Nutrients. 17(444)2025.PubMed/NCBI View Article : Google Scholar

5 

McRae MP: Dietary fiber is beneficial for the prevention of cardiovascular disease: An umbrella review of meta-analyses. J Chiropr Med. 16:289–299. 2017.PubMed/NCBI View Article : Google Scholar

6 

Morelli MB, Gambardella J, Castellanos V, Trimarco V and Santulli G: Vitamin C and cardiovascular disease: An update. Antioxidants (Basel). 9(1227)2020.PubMed/NCBI View Article : Google Scholar

7 

Moser MA and Chun OK: Vitamin C and heart health: A review based on findings from epidemiologic studies. Int J Mol Sci. 17(1328)2016.PubMed/NCBI View Article : Google Scholar

8 

Xu Y, Zheng H, Slabu I, Liehn EA and Rusu M: Vitamin C in cardiovascular disease: From molecular mechanisms to clinical evidence and therapeutic applications. Antioxidants (Basel). 14(506)2025.PubMed/NCBI View Article : Google Scholar

9 

Brownlee I, Fairclough A, Hall A and Paxman J: Dietary seaweed and human health. In: Culinary Arts, Sciences VII: Global, National and Local Perspectives. Bournemouth University UK, Bournemouth University International Centre for Tourism and Hospitality Research, pp82-88, 2011.

10 

Mohibbullah M, Amin A, Talha MA, Baten MA, Rana MM, Sabuz AA, Newaz AW and Choi JS: Physicochemical and nutritional characteristics of cookies prepared with untapped seaweed Ulva intestinalis: An approach to value addition as a functional food. Foods. 12(205)2023.PubMed/NCBI View Article : Google Scholar

11 

Santhoshkumar P, Yoha KS and Moses JA: Drying of seaweed: Approaches, challenges and research needs. Trends in Food Sci Technol. 138:153–163. 2023.PubMed/NCBI View Article : Google Scholar

12 

Kesuma CP, Adi AC and Muniroh L: The effect of seaweed (Eucheuma cottonii) and oyster mushroom (Pleurotus ostreatus) substitution on the acceptability and fiber content of biscuits. Media Gizi Indonesia. 10:146–150. 2017.https://e-journal.unair.ac.id/MGI/article/view/3320.

13 

He Y, Wang B, Wen L, Wang F, Yu H, Chen D, Su X and Zhang C: Effects of dietary fiber on human health. Food Sci Hum Wellness. 11:1–10. 2022.

14 

Nweze CC, Nebechukwu EW and Bawa MY: Dietary fiber and risk of coronary heart diseases. GSC Adv Res Rev. 9:001–009. 2021.

15 

Gill SK, Rossi M, Bajka B and Whelan K: Dietary fibre in gastrointestinal health and disease. Nat Rev Gastroenterol Hepatol. 18:101–116. 2021.PubMed/NCBI View Article : Google Scholar

16 

Maghfuroh N and Hafiludin H: The potential of seaweed powder (Eucheuma cottonii) as an anti-free radical ultra violet body lotion. J Mar Res. 13:753–764. 2024.https://ejournal3.undip.ac.id/index.php/jmr/article/view/44343.

17 

Yanuarti R, Nurjanah Anwar E and Pratama G: The content of vitamin C and E on seaweed porridge Eucheuma cottonii and turbinaria conoides. Marinade. 1:10–16. 2018.

18 

Isola G, Polizzi A, Muraglie S, Leonardi R and Giudice AL: Assessment of vitamin C and antioxidant profiles in saliva and serum in patients with periodontitis and ischemic heart disease. Nutrients. 11(2956)2019.PubMed/NCBI View Article : Google Scholar

19 

Sari DK, Deza A, Ilma IA and Lestari RSD: Comparison of test methods for total phenolic content of seaweed extract of Eucheuma cottonii lontar Banten. Teknika Jurnal Sains dan Teknologi. 14:39–46. 2018.https://jurnal.untirta.ac.id/index.php/ju-tek/article/view/5858/4203.

20 

Antony A and Farid M: Effect of temperatures on polyphenols during extraction. App Sci. 12(2107)2022.

21 

Giglio RV, Patti AM, Cicero AFG, Lippi G, Rizzo M, Toth PP and Banach M: Polyphenols: Potential use in the prevention and treatment of cardiovascular diseases. Curr Pharm Des. 24:239–258. 2018.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
Copy and paste a formatted citation
Spandidos Publications style
Bolu Y, Widiany F and Wahyuningsih S: Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies. Int J Funct Nutr 7: 3, 2026.
APA
Bolu, Y., Widiany, F., & Wahyuningsih, S. (2026). Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies. International Journal of Functional Nutrition, 7, 3. https://doi.org/10.3892/ijfn.2026.55
MLA
Bolu, Y., Widiany, F., Wahyuningsih, S."Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies". International Journal of Functional Nutrition 7.1 (2026): 3.
Chicago
Bolu, Y., Widiany, F., Wahyuningsih, S."Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies". International Journal of Functional Nutrition 7, no. 1 (2026): 3. https://doi.org/10.3892/ijfn.2026.55
Copy and paste a formatted citation
x
Spandidos Publications style
Bolu Y, Widiany F and Wahyuningsih S: Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies. Int J Funct Nutr 7: 3, 2026.
APA
Bolu, Y., Widiany, F., & Wahyuningsih, S. (2026). Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies. International Journal of Functional Nutrition, 7, 3. https://doi.org/10.3892/ijfn.2026.55
MLA
Bolu, Y., Widiany, F., Wahyuningsih, S."Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies". International Journal of Functional Nutrition 7.1 (2026): 3.
Chicago
Bolu, Y., Widiany, F., Wahyuningsih, S."Analysis of the dietary fiber, vitamin C and polyphenol content with seaweed (<em>Eucheuma cottonii</em>) flour substitution in cookies". International Journal of Functional Nutrition 7, no. 1 (2026): 3. https://doi.org/10.3892/ijfn.2026.55
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team