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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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February 2003 Volume 11 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February 2003 Volume 11 Issue 2

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Article

Cloning and characterization of a novel splice variant of the brain-specific protein densin-180

  • Authors:
    • Liu Wang
    • Jian Xu
    • Qihan Wu
    • Jianfeng Dai
    • Xin Ye
    • Li Zeng
    • Chaoneng Ji
    • Shaohua Gu
    • Robert Chunhua Zhao
    • Yi Xie
    • Yumin Mao

  • View Affiliations / Copyright

    Affiliations: State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, P.R. China
  • Pages: 257-260
    |
    Published online on: February 1, 2003
       https://doi.org/10.3892/ijmm.11.2.257
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Abstract

Densin-180 is a brain-specific synaptic protein of the o-sialoglycoprotein family. It functions in specific adhesion between presynaptic and postsynaptic membranes at glutamatergic synapses. We have cloned a novel splice variant of densin-180 from a fetal brain cDNA library and termed it LRRC7. It is located on 1p31 and consists of 8 exons. It encodes a putative protein of 216 amino acids which contains a nuclear localization signal and four leucine-rich repeats (LRRs). LRRs are 20-29 residue sequence motifs present in a number of proteins with diverse functions. Expression analysis of LRRC7 shows it is expressed ubiquitously while its splice variant densin-180 is brain-specific.

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Copy and paste a formatted citation
Spandidos Publications style
Wang L, Xu J, Wu Q, Dai J, Ye X, Zeng L, Ji C, Gu S, Zhao RC, Xie Y, Xie Y, et al: Cloning and characterization of a novel splice variant of the brain-specific protein densin-180. Int J Mol Med 11: 257-260, 2003.
APA
Wang, L., Xu, J., Wu, Q., Dai, J., Ye, X., Zeng, L. ... Mao, Y. (2003). Cloning and characterization of a novel splice variant of the brain-specific protein densin-180. International Journal of Molecular Medicine, 11, 257-260. https://doi.org/10.3892/ijmm.11.2.257
MLA
Wang, L., Xu, J., Wu, Q., Dai, J., Ye, X., Zeng, L., Ji, C., Gu, S., Zhao, R. C., Xie, Y., Mao, Y."Cloning and characterization of a novel splice variant of the brain-specific protein densin-180". International Journal of Molecular Medicine 11.2 (2003): 257-260.
Chicago
Wang, L., Xu, J., Wu, Q., Dai, J., Ye, X., Zeng, L., Ji, C., Gu, S., Zhao, R. C., Xie, Y., Mao, Y."Cloning and characterization of a novel splice variant of the brain-specific protein densin-180". International Journal of Molecular Medicine 11, no. 2 (2003): 257-260. https://doi.org/10.3892/ijmm.11.2.257
Copy and paste a formatted citation
x
Spandidos Publications style
Wang L, Xu J, Wu Q, Dai J, Ye X, Zeng L, Ji C, Gu S, Zhao RC, Xie Y, Xie Y, et al: Cloning and characterization of a novel splice variant of the brain-specific protein densin-180. Int J Mol Med 11: 257-260, 2003.
APA
Wang, L., Xu, J., Wu, Q., Dai, J., Ye, X., Zeng, L. ... Mao, Y. (2003). Cloning and characterization of a novel splice variant of the brain-specific protein densin-180. International Journal of Molecular Medicine, 11, 257-260. https://doi.org/10.3892/ijmm.11.2.257
MLA
Wang, L., Xu, J., Wu, Q., Dai, J., Ye, X., Zeng, L., Ji, C., Gu, S., Zhao, R. C., Xie, Y., Mao, Y."Cloning and characterization of a novel splice variant of the brain-specific protein densin-180". International Journal of Molecular Medicine 11.2 (2003): 257-260.
Chicago
Wang, L., Xu, J., Wu, Q., Dai, J., Ye, X., Zeng, L., Ji, C., Gu, S., Zhao, R. C., Xie, Y., Mao, Y."Cloning and characterization of a novel splice variant of the brain-specific protein densin-180". International Journal of Molecular Medicine 11, no. 2 (2003): 257-260. https://doi.org/10.3892/ijmm.11.2.257
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