Expression of the novel Snai-related zinc-finger transcription factor gene Smuc during mouse development

  • Authors:
    • Xin Zhuge
    • Hiroshi Kataoka
    • Makoto Tanaka
    • Toshinori Murayama
    • Takahiro Kawamoto
    • Hideto Sano
    • Kiyonori Togi
    • Ryoko Yamauchi
    • Yukihiko Ueda
    • Yang Xu
    • Shin-Ichi Nishikawa
    • Toru Kita
    • Masayuki Yokode
  • View Affiliations

  • Published online on: June 1, 2005     https://doi.org/10.3892/ijmm.15.6.945
  • Pages: 945-948
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Abstract

The Snai-related proteins are zinc-finger transcription factors that play important roles in cell-fate determination. We previously cloned a novel Snai-related gene known as snail-related transcription factor of muscle cells (Smuc) or, more recently, as snail homologue 3 (Snai3). In the present study, we investigated the functional roles of Smuc using in situ hybridization analysis at various stages of mouse development. Smuc was not detected until 12.5 days post-coitus (dpc). Its expression was observed in the skeletal muscles and thymus at 13.5 and 15.5 dpc, respectively, and these remained the major sites of Smuc expression until postnatal day 2. No Smuc expression was observed in the heart, large vessels, lungs, liver, kidney or brain. These results indicate that Smuc might be involved in the morphogenesis of the skeletal muscles and thymus at a relatively late stage of mouse development.

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June 2005
Volume 15 Issue 6

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Zhuge X, Kataoka H, Tanaka M, Murayama T, Kawamoto T, Sano H, Togi K, Yamauchi R, Ueda Y, Xu Y, Xu Y, et al: Expression of the novel Snai-related zinc-finger transcription factor gene Smuc during mouse development. Int J Mol Med 15: 945-948, 2005
APA
Zhuge, X., Kataoka, H., Tanaka, M., Murayama, T., Kawamoto, T., Sano, H. ... Yokode, M. (2005). Expression of the novel Snai-related zinc-finger transcription factor gene Smuc during mouse development. International Journal of Molecular Medicine, 15, 945-948. https://doi.org/10.3892/ijmm.15.6.945
MLA
Zhuge, X., Kataoka, H., Tanaka, M., Murayama, T., Kawamoto, T., Sano, H., Togi, K., Yamauchi, R., Ueda, Y., Xu, Y., Nishikawa, S., Kita, T., Yokode, M."Expression of the novel Snai-related zinc-finger transcription factor gene Smuc during mouse development". International Journal of Molecular Medicine 15.6 (2005): 945-948.
Chicago
Zhuge, X., Kataoka, H., Tanaka, M., Murayama, T., Kawamoto, T., Sano, H., Togi, K., Yamauchi, R., Ueda, Y., Xu, Y., Nishikawa, S., Kita, T., Yokode, M."Expression of the novel Snai-related zinc-finger transcription factor gene Smuc during mouse development". International Journal of Molecular Medicine 15, no. 6 (2005): 945-948. https://doi.org/10.3892/ijmm.15.6.945