search button

Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet

  • Authors:
    • Yoshihito Nogusa
    • Noriyuki Yanaka
    • Naoki Sumiyoshi
    • Keiko Takeda
    • Norihisa Kato

  • View Affiliations

  • Published online on: March 1, 2006     https://doi.org/10.3892/ijmm.17.3.491
  • Pages: 491-496
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

A differential display was performed to analyze differential gene expression in the brain of mice in association with dietary high beef tallow. Consumption of a high beef tallow diet up-regulated the expression of zinc finger protein ZPR1 mRNA in the brain. Expression of ZPR1 mRNA in the cerebellum and hippocampus was elevated in response to the high beef tallow diet. The increased ZPR1 expression in the neuronal, Neuro-2A cells, caused a significant increase in H2O2-induced cell death. These results suggest that a high beef tallow diet up-regulates ZPR1 mRNA expression in the brain and might increase the vulnerability to oxidative stress.

Related Articles

Journal Cover

March 2006
Volume 17 Issue 3

Print ISSN: 1107-3756
Online ISSN:1791-244X

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 5.4
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 10.7
  • CiteScore Rank: Q1: #35/328 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 0.994
  • SCImago Journal Rank (SJR): 0.922
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
Nogusa Y, Yanaka N, Sumiyoshi N, Takeda K and Kato N: Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet. Int J Mol Med 17: 491-496, 2006
APA
Nogusa, Y., Yanaka, N., Sumiyoshi, N., Takeda, K., & Kato, N. (2006). Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet. International Journal of Molecular Medicine, 17, 491-496. https://doi.org/10.3892/ijmm.17.3.491
MLA
Nogusa, Y., Yanaka, N., Sumiyoshi, N., Takeda, K., Kato, N."Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet". International Journal of Molecular Medicine 17.3 (2006): 491-496.
Chicago
Nogusa, Y., Yanaka, N., Sumiyoshi, N., Takeda, K., Kato, N."Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet". International Journal of Molecular Medicine 17, no. 3 (2006): 491-496. https://doi.org/10.3892/ijmm.17.3.491