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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2006 Volume 17 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Tightly regulated distribution of family members of proteins is related to social property in the open body system (Review)

Junming Luo, Yinsheng Wan
Pages: 411-418
Published online on: 01 March 2006

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Review

Interaction between heat shock protein 70 kDa and calcineurin in cardiovascular systems (Review)

Ashakumary Lakshmikuttyamma, Ponniah Selvakumar, Rajendra K. Sharma
Pages: 419-423
Published online on: 01 March 2006

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Article

Molecular characterization of the zinc finger transcription factor, Osterix

Mitsutoki Hatta, Yoshitaka Yoshimura, Yoshiaki Deyama, Akiyoshi Fukamizu, Kuniaki Suzuki
Pages: 425-430
Published online on: 01 March 2006

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Article

Caspase-8 activation and oxidative stress are involved in the cytotoxic effect of β-amyloid on rat brain microvascular endothelial cells

Marcella Folin, Silvia Baiguera, Lara Fioravanzo, Maria Teresa Conconi, Claudio Grandi, Gastone G. Nussdorfer, Pier Paolo Parnigotto
Pages: 431-435
Published online on: 01 March 2006

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Article

Plasminogen activator inhibitor-1 is locked in active conformation and polymerizes upon binding ligands neutralizing its activity

Jerzy Jankun, Zofia Specht, Maria Szkudlarek, Robert Greenfield, Bhavna Gaikwad, Latchezar Trifonov, Jean Vaugeois, Ansari M. Aleem, Venkatesha Basrur, Steven H. Selman, Maria I. Zavodszky, Ewa Skrzypczak-Jankun
Pages: 437-447
Published online on: 01 March 2006

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Article

Pro-inflammatory signaling by Jun-N-terminal kinase in inflammatory bowel disease

Keiichi Mitsuyama, Asuka Suzuki, Nobuo Tomiyasu, Osamu Tsuruta, Shigehiko Kitazaki, Teiko Takeda, Yoshitaka Satoh, Brydon L. Bennett, Atsushi Toyonaga, Michio Sata
Pages: 449-455
Published online on: 01 March 2006

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Article

Gene expression profile by inhibiting Raf-1 protein kinase in breast cancer cells

Rajshree R. Mewani, Song Tian, Bihua Li, Malika T. Danner, Theresa D. Carr, Sung Lee, Aquilur Rahman, Usha N. Kasid, Mira Jung, Anatoly Dritschilo, Prafulla C. Gokhale
Pages: 457-463
Published online on: 01 March 2006

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Article

Expression of cdc2 and p27(KIP1) phosphorylation in mitotic cells of the human retinoblastoma

Satoru Kase, Kazuhiko Yoshida, Kazuhiro Ohgami, Kenji Shiratori, Yukari Suzuki, Keiichi I. Nakayama, Shigeaki Ohno
Pages: 465-468
Published online on: 01 March 2006

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Article

Expression of telomerase (hTERT) in aldosterone-producing adrenocortical tumors

Daniele Sticchi, Ambrogio Fassina, Chiara Ganzaroli, Cristiana Pasqualetto, Achille Cesare Pessina, Gastone G. Nussdorfer, Gian Paolo Rossi
Pages: 469-474
Published online on: 01 March 2006

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Article

c-Met responsiveness of isolated hepatocytes evaluated in an in vitro de-differentiation model

Kim A. Boost, He-Jin Kim, Tobias Engl, Elsie Oppermann, Dietger Jonas, Anton Oertl, Roman A. Blaheta
Pages: 475-482
Published online on: 01 March 2006

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Review

Gastrointestinal cancer - only a deregulation of stem cell differentiation? (Review)

Daniel Neureiter, Christoph Herold, Matthias Ocker
Pages: 483-489
Published online on: 01 March 2006

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Article

Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet

Yoshihito Nogusa, Noriyuki Yanaka, Naoki Sumiyoshi, Keiko Takeda, Norihisa Kato
Pages: 491-496
Published online on: 01 March 2006

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Article

Effect of a novel water-soluble vitamin E derivative as a cure for TNBS-induced colitis in rats

Yutaka Isozaki, Norimasa Yoshida, Masaaki Kuroda, Tomohisa Takagi, Osamu Handa, Satoshi Kokura, Hiroshi Ichikawa, Yuji Naito, Takeshi Okanoue, Toshikazu Yoshikawa
Pages: 497-502
Published online on: 01 March 2006

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Article

Repeated intravenous injection of recombinant human hepatocyte growth factor ameliorates liver cirrhosis but causes albuminuria in rats

Kazunori Kusumoto, Akio Ido, Akihiro Moriuchi, Toshiya Katsura, Ildeok Kim, Yuka Takahama, Masatsugu Numata, Mayumi Kodama, Satoru Hasuike, Kenji Nagata, Hirofumi Uto, Ken-Ichi Inui, Hirohito Tsubouchi
Pages: 503-509
Published online on: 01 March 2006

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Article

Evaluation of the anti-allergic activity of Citrus unshiu using rat basophilic leukemia RBL-2H3 cells as well as basophils of patients with seasonal allergic rhinitis to pollen

Shoko Kobayashi, Soichi Tanabe
Pages: 511-515
Published online on: 01 March 2006

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Article

Fructokinase activity in rat liver, ileum, parotid gland, pancreas, pancreatic islet, B and non-B islet cell homogenates

Marie-Helene Giroix, Hassan Jijakli, Philippe Courtois, Ying Zhang, Abdullah Sener, Willy J. Malaisse
Pages: 517-522
Published online on: 01 March 2006

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Article

Gene expression in mouse spermatogenesis during ontogenesis

Vincenza Giuffrida, Franca Maria Pezzino, Fabrizio Romano, Laura Litrico, Maria Rita Garofalo, Giorgio Nicotra, Massimo Libra, Fabio D'Amico, Paola Castrogiovanni, Rosa Imbesi, Maurizio Averna, Santo Sanfilippo, Rosario D'Agata, Enzo Vicari, Aldo E. Calogero, Salvatore Travali
Pages: 523-528
Published online on: 01 March 2006

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Article

FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells

Yuriko Katoh, Masaru Katoh
Pages: 529-532
Published online on: 01 March 2006

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Article

Intracellular viability in human non-polarized respiratory epithelial 16 HBE 14o- cells by group B Streptococcus serotype III clinical isolates presenting 162-kb and 183-kb virulence markers

Adriana Sá de São José, Neide Hirome T. Miyazaki, Raphael Hirata, Ana Luiza Mattos-Guaraldi, Prescilla Emy Nagao
Pages: 533-538
Published online on: 01 March 2006

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Article

Six novel mutations of the LDL receptor gene in FH kindred of Sicilian and Paraguayan descent

Angelo B. Cefalù, Giacoma Barraco, Davide Noto, Vincenza Valenti, Carlo M. Barbagallo, Gerardo D. Elisir, Luis A. Cuniberti, José P. Werba, Massimo Libra, Salvatore Costa, Fabrizio Gianguzza, Alberto Notarbartolo, Salvatore Travali, Maurizio R. Averna
Pages: 539-546
Published online on: 01 March 2006

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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