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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2006 Volume 17 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Tightly regulated distribution of family members of proteins is related to social property in the open body system (Review)

Junming Luo, Yinsheng Wan
Pages: 411-418
Published online on: 01 March 2006

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Review

Interaction between heat shock protein 70 kDa and calcineurin in cardiovascular systems (Review)

Ashakumary Lakshmikuttyamma, Ponniah Selvakumar, Rajendra K. Sharma
Pages: 419-423
Published online on: 01 March 2006

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Article

Molecular characterization of the zinc finger transcription factor, Osterix

Mitsutoki Hatta, Yoshitaka Yoshimura, Yoshiaki Deyama, Akiyoshi Fukamizu, Kuniaki Suzuki
Pages: 425-430
Published online on: 01 March 2006

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Article

Caspase-8 activation and oxidative stress are involved in the cytotoxic effect of β-amyloid on rat brain microvascular endothelial cells

Marcella Folin, Silvia Baiguera, Lara Fioravanzo, Maria Teresa Conconi, Claudio Grandi, Gastone G. Nussdorfer, Pier Paolo Parnigotto
Pages: 431-435
Published online on: 01 March 2006

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Article

Plasminogen activator inhibitor-1 is locked in active conformation and polymerizes upon binding ligands neutralizing its activity

Jerzy Jankun, Zofia Specht, Maria Szkudlarek, Robert Greenfield, Bhavna Gaikwad, Latchezar Trifonov, Jean Vaugeois, Ansari M. Aleem, Venkatesha Basrur, Steven H. Selman, Maria I. Zavodszky, Ewa Skrzypczak-Jankun
Pages: 437-447
Published online on: 01 March 2006

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Article

Pro-inflammatory signaling by Jun-N-terminal kinase in inflammatory bowel disease

Keiichi Mitsuyama, Asuka Suzuki, Nobuo Tomiyasu, Osamu Tsuruta, Shigehiko Kitazaki, Teiko Takeda, Yoshitaka Satoh, Brydon L. Bennett, Atsushi Toyonaga, Michio Sata
Pages: 449-455
Published online on: 01 March 2006

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Article

Gene expression profile by inhibiting Raf-1 protein kinase in breast cancer cells

Rajshree R. Mewani, Song Tian, Bihua Li, Malika T. Danner, Theresa D. Carr, Sung Lee, Aquilur Rahman, Usha N. Kasid, Mira Jung, Anatoly Dritschilo, Prafulla C. Gokhale
Pages: 457-463
Published online on: 01 March 2006

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Article

Expression of cdc2 and p27(KIP1) phosphorylation in mitotic cells of the human retinoblastoma

Satoru Kase, Kazuhiko Yoshida, Kazuhiro Ohgami, Kenji Shiratori, Yukari Suzuki, Keiichi I. Nakayama, Shigeaki Ohno
Pages: 465-468
Published online on: 01 March 2006

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Article

Expression of telomerase (hTERT) in aldosterone-producing adrenocortical tumors

Daniele Sticchi, Ambrogio Fassina, Chiara Ganzaroli, Cristiana Pasqualetto, Achille Cesare Pessina, Gastone G. Nussdorfer, Gian Paolo Rossi
Pages: 469-474
Published online on: 01 March 2006

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Article

c-Met responsiveness of isolated hepatocytes evaluated in an in vitro de-differentiation model

Kim A. Boost, He-Jin Kim, Tobias Engl, Elsie Oppermann, Dietger Jonas, Anton Oertl, Roman A. Blaheta
Pages: 475-482
Published online on: 01 March 2006

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Review

Gastrointestinal cancer - only a deregulation of stem cell differentiation? (Review)

Daniel Neureiter, Christoph Herold, Matthias Ocker
Pages: 483-489
Published online on: 01 March 2006

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Article

Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet

Yoshihito Nogusa, Noriyuki Yanaka, Naoki Sumiyoshi, Keiko Takeda, Norihisa Kato
Pages: 491-496
Published online on: 01 March 2006

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Article

Effect of a novel water-soluble vitamin E derivative as a cure for TNBS-induced colitis in rats

Yutaka Isozaki, Norimasa Yoshida, Masaaki Kuroda, Tomohisa Takagi, Osamu Handa, Satoshi Kokura, Hiroshi Ichikawa, Yuji Naito, Takeshi Okanoue, Toshikazu Yoshikawa
Pages: 497-502
Published online on: 01 March 2006

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Article

Repeated intravenous injection of recombinant human hepatocyte growth factor ameliorates liver cirrhosis but causes albuminuria in rats

Kazunori Kusumoto, Akio Ido, Akihiro Moriuchi, Toshiya Katsura, Ildeok Kim, Yuka Takahama, Masatsugu Numata, Mayumi Kodama, Satoru Hasuike, Kenji Nagata, Hirofumi Uto, Ken-Ichi Inui, Hirohito Tsubouchi
Pages: 503-509
Published online on: 01 March 2006

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Article

Evaluation of the anti-allergic activity of Citrus unshiu using rat basophilic leukemia RBL-2H3 cells as well as basophils of patients with seasonal allergic rhinitis to pollen

Shoko Kobayashi, Soichi Tanabe
Pages: 511-515
Published online on: 01 March 2006

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Article

Fructokinase activity in rat liver, ileum, parotid gland, pancreas, pancreatic islet, B and non-B islet cell homogenates

Marie-Helene Giroix, Hassan Jijakli, Philippe Courtois, Ying Zhang, Abdullah Sener, Willy J. Malaisse
Pages: 517-522
Published online on: 01 March 2006

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Article

Gene expression in mouse spermatogenesis during ontogenesis

Vincenza Giuffrida, Franca Maria Pezzino, Fabrizio Romano, Laura Litrico, Maria Rita Garofalo, Giorgio Nicotra, Massimo Libra, Fabio D'Amico, Paola Castrogiovanni, Rosa Imbesi, Maurizio Averna, Santo Sanfilippo, Rosario D'Agata, Enzo Vicari, Aldo E. Calogero, Salvatore Travali
Pages: 523-528
Published online on: 01 March 2006

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Article

FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells

Yuriko Katoh, Masaru Katoh
Pages: 529-532
Published online on: 01 March 2006

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Article

Intracellular viability in human non-polarized respiratory epithelial 16 HBE 14o- cells by group B Streptococcus serotype III clinical isolates presenting 162-kb and 183-kb virulence markers

Adriana Sá de São José, Neide Hirome T. Miyazaki, Raphael Hirata, Ana Luiza Mattos-Guaraldi, Prescilla Emy Nagao
Pages: 533-538
Published online on: 01 March 2006

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Article

Six novel mutations of the LDL receptor gene in FH kindred of Sicilian and Paraguayan descent

Angelo B. Cefalù, Giacoma Barraco, Davide Noto, Vincenza Valenti, Carlo M. Barbagallo, Gerardo D. Elisir, Luis A. Cuniberti, José P. Werba, Massimo Libra, Salvatore Costa, Fabrizio Gianguzza, Alberto Notarbartolo, Salvatore Travali, Maurizio R. Averna
Pages: 539-546
Published online on: 01 March 2006

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Review Open Access

Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Review Open Access

Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Review Open Access

Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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Review Open Access

A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Review Open Access

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Review Open Access

Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Review Open Access

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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