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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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December 2006 Volume 18 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December 2006 Volume 18 Issue 6

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Article

Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release

  • Authors:
    • Witold Malendowicz
    • Marcin Rucinski
    • Anna S. Belloni
    • Agnieszka Ziolkowska
    • Gastone G. Nussdorfer
    • Zbigniew Kwias
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Poznan University of Medical Sciences, PL-60781 Poznan, Poland
  • Pages: 1097-1100
    |
    Published online on: December 1, 2006
       https://doi.org/10.3892/ijmm.18.6.1097
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Abstract

We have recently demonstrated the expression of leptin and leptin receptor (Ob-R) isoforms a, b, c, e and f in the rat seminal vesicles and prostate. The aim of the present study was to provide a semiquantitative real-time PCR estimation of leptin/Ob-R isoform mRNA expression in the seminal vesicles and individual components of rat prostate, and to ascertain the in vitro effects of leptin on prostate acid phosphatase release. The highest expression of the leptin and Ob-R genes was in the seminal vesicles and lateral prostate lobe, respectively. Of the various isoforms, Ob-Rb displayed the highest and Ob-Re the lowest expression. Leptin (10−8 and 10−6 M) enhanced acid phosphate release from seminal vesicles, and (10−6 M) decreased it from the coagulating lobe. Taken together, our findings support the contention that leptin may be involved in the autocrine-paracrine functional regulation of rat seminal vesicles and prostate. The physiological relevance of the marked heterogeneity of the different prostate lobes in both their leptin/Ob-R expression and functional response to leptin remains to be addressed.

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Copy and paste a formatted citation
Spandidos Publications style
Malendowicz W, Rucinski M, Belloni AS, Ziolkowska A, Nussdorfer GG and Kwias Z: Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release. Int J Mol Med 18: 1097-1100, 2006.
APA
Malendowicz, W., Rucinski, M., Belloni, A.S., Ziolkowska, A., Nussdorfer, G.G., & Kwias, Z. (2006). Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release. International Journal of Molecular Medicine, 18, 1097-1100. https://doi.org/10.3892/ijmm.18.6.1097
MLA
Malendowicz, W., Rucinski, M., Belloni, A. S., Ziolkowska, A., Nussdorfer, G. G., Kwias, Z."Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release". International Journal of Molecular Medicine 18.6 (2006): 1097-1100.
Chicago
Malendowicz, W., Rucinski, M., Belloni, A. S., Ziolkowska, A., Nussdorfer, G. G., Kwias, Z."Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release". International Journal of Molecular Medicine 18, no. 6 (2006): 1097-1100. https://doi.org/10.3892/ijmm.18.6.1097
Copy and paste a formatted citation
x
Spandidos Publications style
Malendowicz W, Rucinski M, Belloni AS, Ziolkowska A, Nussdorfer GG and Kwias Z: Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release. Int J Mol Med 18: 1097-1100, 2006.
APA
Malendowicz, W., Rucinski, M., Belloni, A.S., Ziolkowska, A., Nussdorfer, G.G., & Kwias, Z. (2006). Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release. International Journal of Molecular Medicine, 18, 1097-1100. https://doi.org/10.3892/ijmm.18.6.1097
MLA
Malendowicz, W., Rucinski, M., Belloni, A. S., Ziolkowska, A., Nussdorfer, G. G., Kwias, Z."Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release". International Journal of Molecular Medicine 18.6 (2006): 1097-1100.
Chicago
Malendowicz, W., Rucinski, M., Belloni, A. S., Ziolkowska, A., Nussdorfer, G. G., Kwias, Z."Real-time PCR analysis of leptin and leptin receptor expression in the rat prostate, and effects of leptin on prostatic acid phosphatase release". International Journal of Molecular Medicine 18, no. 6 (2006): 1097-1100. https://doi.org/10.3892/ijmm.18.6.1097
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