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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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December 2006 Volume 18 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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December 2006 Volume 18 Issue 6

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Article

Expression of neuropeptides B and W and their receptors in endocrine glands of the rat

  • Authors:
    • Anna Hochol
    • Anna S. Belloni
    • Marcin Rucinski
    • Agnieszka Ziolkowska
    • Rosa Di Liddo
    • Gastone G. Nussdorfer
    • Ludwik K. Malendowicz
  • View Affiliations / Copyright

    Affiliations: Department of Histology and Embryology, Poznan School of Medicine, PL-60781 Poznan, Poland
  • Pages: 1101-1106
    |
    Published online on: December 1, 2006
       https://doi.org/10.3892/ijmm.18.6.1101
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Abstract

Neuropeptides B and W (NPB and NPW) have been identified as endogenous ligands of the G protein-coupled receptors (GPR) 7 and 8, which in humans are expressed in the hypothalamus and probably involved in the regulation of energy homeostasis and feeding behavior. GPR8 is absent in the rat, where the GPR8-like receptor (GPR8-LR) has been described. Reverse transcription-polymerase chain reaction detected the expression of NPB, NPW, GPR7 and GPR8-LR mRNAs in the hypothalamus, anterior pituitary, thyroid and parathyroid glands, pancreatic islets, adrenal glands, ovary and testis of the rat. Immunocytochemistry demonstrated the presence of NPB and NPW immunoreactivities in these same glands. Radioimmune assay showed that the bolus intraperitoneal injection of 2 nmol/100 g NPB or NPW raised the plasma levels of parathyroid hormone, corticosterone and testosterone. NPB also increased the blood concentration of thyroxine, and NPW that of ACTH and estradiol. Taken together, these findings allow us to suggest that NPB and NPW play a role in the autocrine-paracrine functional regulation of the endocrine system in the rat.

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Copy and paste a formatted citation
Spandidos Publications style
Hochol A, Belloni AS, Rucinski M, Ziolkowska A, Di Liddo R, Nussdorfer GG and Malendowicz LK: Expression of neuropeptides B and W and their receptors in endocrine glands of the rat. Int J Mol Med 18: 1101-1106, 2006.
APA
Hochol, A., Belloni, A.S., Rucinski, M., Ziolkowska, A., Di Liddo, R., Nussdorfer, G.G., & Malendowicz, L.K. (2006). Expression of neuropeptides B and W and their receptors in endocrine glands of the rat. International Journal of Molecular Medicine, 18, 1101-1106. https://doi.org/10.3892/ijmm.18.6.1101
MLA
Hochol, A., Belloni, A. S., Rucinski, M., Ziolkowska, A., Di Liddo, R., Nussdorfer, G. G., Malendowicz, L. K."Expression of neuropeptides B and W and their receptors in endocrine glands of the rat". International Journal of Molecular Medicine 18.6 (2006): 1101-1106.
Chicago
Hochol, A., Belloni, A. S., Rucinski, M., Ziolkowska, A., Di Liddo, R., Nussdorfer, G. G., Malendowicz, L. K."Expression of neuropeptides B and W and their receptors in endocrine glands of the rat". International Journal of Molecular Medicine 18, no. 6 (2006): 1101-1106. https://doi.org/10.3892/ijmm.18.6.1101
Copy and paste a formatted citation
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Spandidos Publications style
Hochol A, Belloni AS, Rucinski M, Ziolkowska A, Di Liddo R, Nussdorfer GG and Malendowicz LK: Expression of neuropeptides B and W and their receptors in endocrine glands of the rat. Int J Mol Med 18: 1101-1106, 2006.
APA
Hochol, A., Belloni, A.S., Rucinski, M., Ziolkowska, A., Di Liddo, R., Nussdorfer, G.G., & Malendowicz, L.K. (2006). Expression of neuropeptides B and W and their receptors in endocrine glands of the rat. International Journal of Molecular Medicine, 18, 1101-1106. https://doi.org/10.3892/ijmm.18.6.1101
MLA
Hochol, A., Belloni, A. S., Rucinski, M., Ziolkowska, A., Di Liddo, R., Nussdorfer, G. G., Malendowicz, L. K."Expression of neuropeptides B and W and their receptors in endocrine glands of the rat". International Journal of Molecular Medicine 18.6 (2006): 1101-1106.
Chicago
Hochol, A., Belloni, A. S., Rucinski, M., Ziolkowska, A., Di Liddo, R., Nussdorfer, G. G., Malendowicz, L. K."Expression of neuropeptides B and W and their receptors in endocrine glands of the rat". International Journal of Molecular Medicine 18, no. 6 (2006): 1101-1106. https://doi.org/10.3892/ijmm.18.6.1101
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