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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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January 2011 Volume 27 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations

  • Authors:
    • Louiza Belkacemi
    • Ghalem Selselet-Attou
    • Nurdan Bulur
    • Karim Louchami
    • Abdullah Sener
    • Willy J. Malaisse

  • View Affiliations / Copyright

    Affiliations: Laboratoire de Technologie Alimentaire et Nutrition, Université de Mostaganem, Mostaganem, Algeria, Laboratory of Experimental Hormonology, Université Libre de Bruxelles, 808 Route de Lennik, B-1070 Brussels, Belgium
  • Pages: 95-102
    |
    Published online on: November 10, 2010
       https://doi.org/10.3892/ijmm.2010.556
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Abstract

The present report concerns several post-mortem variables examined in sand rats that were either maintained on a vegetal diet (control animals) or exposed first during a 20-day transition period to a mixed diet consisting of a fixed amount of a hypercaloric food and decreasing amounts of the vegetal food and then to a 30-day experimental period of exposure to the hypercaloric food. During the latter period, all animals were either given free access to food or fasting daily for 15 h, i.e. from 5.00 p.m. to 8.00 a.m. The body weight, liver wet weight, pancreas wet weight, plasma glucose and haemoglobin A1c concentration, plasma insulin concentration, insulinogenic index, insulin resistance HOMA, plasma cholesterol and triglyceride concentration, liver triglyceride and phospholipid content were all measured. Pancreatic islet (insulin, GLUT2) and liver (lipid droplets) histology were also examined. The main findings consisted in a lower body weight of fasting than non-fasting animals, a higher liver weight in non-diabetic and diabetic rats than in control non-fasting (but not so in fasting) animals, a decrease of pancreas weight in non-diabetic and diabetic as distinct from control animals, a fasting-induced decrease in plasma glucose, plasma insulin and insulin resistance HOMA, plasma cholesterol and triglyceride concentration and triglyceride liver content.

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Copy and paste a formatted citation
Spandidos Publications style
Belkacemi L, Selselet-Attou G, Bulur N, Louchami K, Sener A and Malaisse WJ: Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations. Int J Mol Med 27: 95-102, 2011.
APA
Belkacemi, L., Selselet-Attou, G., Bulur, N., Louchami, K., Sener, A., & Malaisse, W.J. (2011). Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations. International Journal of Molecular Medicine, 27, 95-102. https://doi.org/10.3892/ijmm.2010.556
MLA
Belkacemi, L., Selselet-Attou, G., Bulur, N., Louchami, K., Sener, A., Malaisse, W. J."Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations". International Journal of Molecular Medicine 27.1 (2011): 95-102.
Chicago
Belkacemi, L., Selselet-Attou, G., Bulur, N., Louchami, K., Sener, A., Malaisse, W. J."Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations". International Journal of Molecular Medicine 27, no. 1 (2011): 95-102. https://doi.org/10.3892/ijmm.2010.556
Copy and paste a formatted citation
x
Spandidos Publications style
Belkacemi L, Selselet-Attou G, Bulur N, Louchami K, Sener A and Malaisse WJ: Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations. Int J Mol Med 27: 95-102, 2011.
APA
Belkacemi, L., Selselet-Attou, G., Bulur, N., Louchami, K., Sener, A., & Malaisse, W.J. (2011). Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations. International Journal of Molecular Medicine, 27, 95-102. https://doi.org/10.3892/ijmm.2010.556
MLA
Belkacemi, L., Selselet-Attou, G., Bulur, N., Louchami, K., Sener, A., Malaisse, W. J."Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations". International Journal of Molecular Medicine 27.1 (2011): 95-102.
Chicago
Belkacemi, L., Selselet-Attou, G., Bulur, N., Louchami, K., Sener, A., Malaisse, W. J."Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations". International Journal of Molecular Medicine 27, no. 1 (2011): 95-102. https://doi.org/10.3892/ijmm.2010.556
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