Virus capture using anionic polymer-coated magnetic beads (Review)

Sakudo,Akikazu; Onodera,Takashi

doi:10.3892/ijmm.2012.962

July 2012 Volume 30 Issue 1

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July 2012 Volume 30 Issue 1

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Review

Virus capture using anionic polymer-coated magnetic beads (Review)

Authors:
- Akikazu Sakudo
- Takashi Onodera
View Affiliations / Copyright

Affiliations: Laboratory of Biometabolic Chemistry, School of Health Sciences, Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa 903-0215, Japan, Department of Molecular Immunology, School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
Pages: 3-7
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Published online on: April 10, 2012

https://doi.org/10.3892/ijmm.2012.962
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Abstract

The recent incidence of emerging and re-emerging viruses is a serious health concern worldwide. The development of transportation systems, such as air travel, has increased the risk of a global pandemic caused by emerging viruses. Agents causing novel infections are often zoonotic, crossing from the natural host into the human population. Hence, comprehensive surveillance of virus-infected animals as well as humans is required. However, the number of virus particles in clinical and environmental samples is usually very low. Thus, a method to concentrate the virus is sometimes required in order to enable detection. We recently reported that magnetic beads coated with an anionic polymer, poly(methyl vinyl ether-maleic anhydride) can be used to facilitate the rapid and sensitive detection of viruses. In this review, we describe recent developments for concentrating viruses using anionic magnetic beads.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Virus capture using anionic polymer-coated magnetic beads (Review)

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Abstract

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