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Discover the most frequently read articles from the past month
Review

Mitochondrial electron transport chain, ROS generation and uncoupling (Review)
Ru‑Zhou Zhao, Shuai Jiang, Lin Zhang, Zhi‑Bin Yu
Pages: 3-15 Published online on: 08 May 2019
Review
MRI contrast agents: Classification and application (Review)
Yu-Dong Xiao, Ramchandra Paudel, Jun Liu, Cong Ma, Zi-Shu Zhang, Shun-Ke Zhou
Pages: 1319-1326 Published online on: 21 September 2016
Review

Precision medicine for human cancers with Notch signaling dysregulation (Review)
Masuko Katoh, Masaru Katoh
Pages: 279-297 Published online on: 04 December 2019
Review

The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review)
Fatima Ardito, Michele Giuliani, Donatella Perrone, Giuseppe Troiano, Lorenzo Lo Muzio
Pages: 271-280 Published online on: 22 June 2017
Article

Tanshinone IIA protects against chronic obstructive pulmonary disease via exosome‑shuttled miR‑486‑5p
Dongdong Tian, Yingchun Miao, Wendong Hao, Ning Yang, Ping Wang, Qingyi Ge, Cailian Zhang
Article Number: 97 Published online on: 27 May 2022
Article

ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade
Valerio Ciccone, Erika Terzuoli, Emma Ristori, Arianna Filippelli, Marina Ziche, Lucia Morbidelli, Sandra Donnini
Article Number: 99 Published online on: 02 June 2022
Article

GATA1 regulates the microRNA‑328‑3p/PIM1 axis via circular RNA ITGB1 to promote renal ischemia/reperfusion injury in HK‑2 cells
Yang Gao, Weijia Xu, Chen Guo, Tao Huang
Article Number: 100 Published online on: 07 June 2022
Review

Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)
Anatoly V. Skalny, Lothar Rink, Olga P. Ajsuvakova, Michael Aschner, Viktor A. Gritsenko, Svetlana I. Alekseenko, Andrey A. Svistunov, Demetrios Petrakis, Demetrios A. Spandidos, Jan Aaseth, Aristidis Tsatsakis, Alexey A. Tinkov
Pages: 17-26 Published online on: 14 April 2020
Article

Rifaximin enhances the L‑carnitine‑mediated preventive effects on skeletal muscle atrophy in cirrhotic rats by modulating the gut‑liver‑muscle axis
Koji Murata, Kosuke Kaji, Norihisa Nishimura, Masahide Enomoto, Yuki Fujimoto, Soichi Takeda, Yuki Tsuji, Yukihisa Fujinaga, Hiroaki Takaya, Hideto Kawaratani, Tadashi Namisaki, Takemi Akahane, Hitoshi Yoshiji
Article Number: 101 Published online on: 09 June 2022
Article

Topical application of Porphyromonas gingivalis into the gingival pocket in mice leads to chronic‑active infection, periodontitis and systemic inflammation
Sharon Kim, Yasuhiko Bando, Chungyu Chang, Jeonga Kwon, Berta Tarverti, Doohyun Kim, Sung Hee Lee, Hung Ton-That, Reuben Kim, Peter L. Nara, No-Hee Park
Article Number: 103 Published online on: 15 June 2022
Review

An update on the functional roles of long non‑coding RNAs in ischemic injury (Review)
Yanqun Cao, Jia Liu, Quzhe Lu, Kai Huang, Baolin Yang, James Reilly, Na Jiang, Xinhua Shu, Lei Shang
Article Number: 91 Published online on: 18 May 2022
Article

Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation
Yanting Wang, Wanli Xie, Yiqi Feng, Zhenzhen Xu, Yuyao He, Yue Xiong, Lu Chen, Xia Li, Jie Liu, Guoyang Liu, Qingping Wu
Article Number: 96 Published online on: 25 May 2022
Article

Comparison of isolation methods of exosomes and exosomal RNA from cell culture medium and serum
Yue-Ting Tang, Yi-Yao Huang, Lei Zheng, Si-Hua Qin, Xu-Ping Xu, Tai-Xue An, Yong Xu, Ying-Song Wu, Xiu-Mei Hu, Bao-Hong Ping, Qian Wang
Pages: 834-844 Published online on: 24 July 2017
Review

Current and innovative methods for the diagnosis of COVID‑19 infection (Review)
Luca Falzone, Giuseppe Gattuso, Aristidis Tsatsakis, Demetrios A. Spandidos, Massimo Libra
Article Number: 100 Published online on: 12 April 2021
Article

Development of a cancer cells self‑activating and miR‑125a‑5p expressing poly‑pharmacological nanodrug for cancer treatment
Yung-Chieh Chang, Min-Chieh Shieh, Yen-Hsuan Chang, Wei-Lun Huang, Wu-Chou Su, Fong-Yu Cheng, Chun Hei Antonio Cheung
Article Number: 102 Published online on: 14 June 2022
Article

Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway
Yuqiang Shan, Jiaotao Li, Akao Zhu, Wencheng Kong, Rongchao Ying, Weiming Zhu
Article Number: 89 Published online on: 16 May 2022
Review

Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review)
Masaru Katoh
Pages: 713-725 Published online on: 17 May 2018
Review
Cigarette smoking and gastrointestinal diseases: The causal relationship and underlying molecular mechanisms (Review)
L. F. Li, R. L.Y. Chan, L. Lu, J. Shen, L. Zhang, W. K.K. Wu, L. Wang, T. Hu, M. X. Li, C. H. Cho
Pages: 372-380 Published online on: 22 May 2014
Review

Towards effective COVID‑19 vaccines: Updates, perspectives and challenges (Review)
Daniela Calina, Anca Oana Docea, Demetrios Petrakis, Alex M. Egorov, Aydar A. Ishmukhametov, Alexsandr G. Gabibov, Michael I. Shtilman, Ronald Kostoff, Félix Carvalho, Marco Vinceti, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 3-16 Published online on: 06 May 2020
Review
