|
1
|
Garcia-Barros M, Paris F, Cordon-Cardo C,
Lyden D, Rafii S, Haimovitz-Friedman A, Fuks Z and Kolesnick R:
Tumor response to radiotherapy regulated by endothelial cell
apoptosis. Science. 300:1155–1159. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Li J, Huang S, Armstrong EA, Fowler JF and
Harari PM: Angiogenesis and radiation response modulation after
vascular endothelial growth factor receptor-2 (VEGFR2) blockade.
Int J Radiat Oncol Biol Phys. 62:1477–1485. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Gunes C, Lichtsteiner S, Vasserot AP and
Englert C: Expression of the hTERT gene is regulated at the level
of transcriptional initiation and repressed by Mad1. Cancer Res.
60:2116–2121. 2000.PubMed/NCBI
|
|
4
|
Calado RT and Young NS: Telomere diseases.
N Engl J Med. 361:2353–2365. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Grimes A and Chandra SB: Significance of
cellular senescence in aging and cancer. Cancer Res Treat.
41:187–195. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Nakamura M, Masutomi K, Kyo S, Hashimoto
M, Maida Y, Kanaya T, Tanaka M, Hahn WC and Inoue M: Efficient
inhibition of human telomerase reverse transcriptase expression by
RNA interference sensitizes cancer cells to ionizing radiation and
chemotherapy. Hum Gene Ther. 16:859–868. 2005. View Article : Google Scholar
|
|
7
|
Pallini R, Pierconti F, Falchetti ML,
D’Arcangelo D, Fernandez E, Maira G, D’Ambrosio E and Larocca LM:
Evidence for telomerase involvement in the angiogenesis of
astrocytic tumors: expression of human telomerase reverse
transcriptase messenger RNA by vascular endothelial cells. J
Neurosurg. 94:961–971. 2001. View Article : Google Scholar
|
|
8
|
Falchetti ML, Mongiardi MP, Fiorenzo P,
Petrucci G, Pierconti F, D’Agnano I, D’Alessandris G, Alessandri G,
Gelati M, Ricci-Vitiani L, Maira G, Larocca LM, Levi A and Pallini
R: Inhibition of telomerase in the endothelial cells disrupts tumor
angiogenesis in glioblastoma xenografts. Int J Cancer.
122:1236–1242. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Bu DX, Johansson ME, Ren J, Xu DW, Johnson
FB, Edfeldt K and Yan ZQ: Nuclear factor {kappa}B-mediated
transactivation of telomerase prevents intimal smooth muscle cell
from replicative senescence during vascular repair. Arterioscler
Thromb Vasc Biol. 30:2604–2610. 2010.
|
|
10
|
Dvorak HF: Vascular permeability
factor/vascular endothelial growth factor: a critical cytokine in
tumor angiogenesis and a potential target for diagnosis and
therapy. J Clin Oncol. 20:4368–4380. 2002. View Article : Google Scholar
|
|
11
|
Damianovich D and Tebbutt NC: Role of
novel targeted agents in the treatment of metastatic colorectal
cancer. Asia Pac J Clin Oncol. 3:2–11. 2007. View Article : Google Scholar
|
|
12
|
Watanabe Y, Lee SW, Detmar M, Ajioka I and
Dvorak HF: Vascular permeability factor/vascular endothelial growth
factor (VPF/VEGF) delays and induces escape from senescence in
human dermal microvascular endothelial cells. Oncogene.
14:2025–2032. 1997. View Article : Google Scholar
|
|
13
|
Seegar TC, Eller B, Tzvetkova-Robev D,
Kolev MV, Henderson SC, Nikolov DB and Barton WA: Tie1-Tie2
interactions mediate functional differences between angiopoietin
ligands. Mol Cell. 37:643–655. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kurz DJ, Hong Y, Trivier E, Huang HL,
Decary S, Zang GH, Luscher TF and Erusalimsky JD: Fibroblast growth
factor-2, but not vascular endothelial growth factor, upregulates
telomerase activity in human endothelial cells. Arterioscler Thromb
Vasc Biol. 23:748–754. 2003. View Article : Google Scholar
|
|
15
|
Oliner J, Min H, Leal J, Yu D, Rao S, You
E, Tang X, Kim H, Meyer S, Han SJ, Hawkins N, Rosenfeld R, Davy E,
Graham K, Jacobsen F, Stevenson S, Ho J, Chen Q, Hartmann T,
Michaels M, Kelley M, Li L, Sitney K, Martin F, Sun JR, Zhang N, Lu
J, Estrada J, Kumar R, Coxon A, Kaufman S, Pretorius J, Scully S,
Cattley R, Payton M, Coats S, Nguyen L, Desilva B, Ndifor A,
Hayward I, Radinsky R, Boone T and Kendall R: Suppression of
angiogenesis and tumor growth by selective inhibition of
angiopoietin-2. Cancer Cell. 6:507–516. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
St Croix B, Rago C, Velculescu V, Traverso
G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C,
Vogelstein B and Kinzler KW: Genes expressed in human tumor
endothelium. Science. 289:1197–1202. 2000.PubMed/NCBI
|
|
17
|
Kalluri R: Basement membranes: structure,
assembly and role in tumour angiogenesis. Nat Rev Cancer.
3:422–433. 2003. View
Article : Google Scholar : PubMed/NCBI
|
|
18
|
Durai R, Yang SY, Sales KM, Seifalian AM,
Goldspink G and Winslet MC: Insulin-like growth factor binding
protein-4 gene therapy increases apoptosis by altering Bcl-2 and
Bax proteins and decreases angiogenesis in colorectal cancer. Int J
Oncol. 30:883–888. 2007.
|
|
19
|
Roth JM, Akalu A, Zelmanovich A,
Policarpio D, Ng B, MacDonald S, Formenti S, Liebes L and Brooks
PC: Recombinant alpha2(IV)NC1 domain inhibits tumor
cell-extracellular matrix interactions, induces cellular
senescence, and inhibits tumor growth in vivo. Am J Pathol.
166:901–911. 2005. View Article : Google Scholar
|
|
20
|
Itasaka S, Komaki R, Herbst RS, Shibuya K,
Shintani T, Hunter NR, Onn A, Bucana CD, Milas L, Ang KK and
O’Reilly MS: Endostatin improves radioresponse and blocks tumor
revascularization after radiation therapy for A431 xenografts in
mice. Int J Radiat Oncol Biol Phys. 67:870–878. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Ria R, Todoerti K, Berardi S, Coluccia AM,
De Luisi A, Mattioli M, Ronchetti D, Morabito F, Guarini A,
Petrucci MT, Dammacco F, Ribatti D, Neri A and Vacca A: Gene
expression profiling of bone marrow endothelial cells in patients
with multiple myeloma. Clin Cancer Res. 15:5369–5378. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Hong EH, Lee SJ, Kim JS, Lee KH, Um HD,
Kim JH, Kim SJ, Kim JI and Hwang SG: Ionizing radiation induces
cellular senescence of articular chondrocytes via negative
regulation of SIRT1 by p38 kinase. J Biol Chem. 285:1283–1295.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Igarashi K, Sakimoto I, Kataoka K, Ohta K
and Miura M: Radiation-induced senescence-like phenotype in
proliferating and plateau-phase vascular endothelial cells. Exp
Cell Res. 313:3326–3336. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
d’Adda di Fagagna F, Reaper PM,
Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G,
Carter NP and Jackson SP: A DNA damage checkpoint response in
telomere-initiated senescence. Nature. 426:194–198. 2003.PubMed/NCBI
|
|
25
|
Kim NW, Piatyszek MA, Prowse KR, Harley
CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL and Shay
JW: Specific association of human telomerase activity with immortal
cells and cancer. Science. 266:2011–2015. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Takano H, Murasawa S and Asahara T:
Functional and gene expression analysis of hTERT overexpressed
endothelial cells. Biologics. 2:547–554. 2008.PubMed/NCBI
|
|
27
|
Wu X, Smavadati S, Nordfjall K, Karlsson
K, Qvarnstrom F, Simonsson M, Bergqvist M, Gryaznov S, Ekman S and
Paulsson-Karlsson Y: Telomerase antagonist imetelstat inhibits
esophageal cancer cell growth and increases radiation-induced DNA
breaks. Biochim Biophys Acta. 1823:2130–2135. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lin SY and Elledge SJ: Multiple tumor
suppressor pathways negatively regulate telomerase. Cell.
113:881–889. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Mezquita P, Parghi SS, Brandvold KA and
Ruddell A: Myc regulates VEGF production in B cells by stimulating
initiation of VEGF mRNA translation. Oncogene. 24:889–901. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zaccagnini G, Gaetano C, Della Pietra L,
Nanni S, Grasselli A, Mangoni A, Benvenuto R, Fabrizi M, Truffa S,
Germani A, Moretti F, Pontecorvi A, Sacchi A, Bacchetti S,
Capogrossi MC and Farsetti A: Telomerase mediates vascular
endothelial growth factor-dependent responsiveness in a rat model
of hind limb ischemia. J Biol Chem. 280:14790–14798. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Tian F, Liang PH and Li LY: Inhibition of
endothelial progenitor cell differentiation by VEGI. Blood.
113:5352–5360. 2009. View Article : Google Scholar : PubMed/NCBI
|
