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Article

MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression

Retraction in: /10.3892/ijmm.2021.5003
  • Authors:
    • Qinggang Tian
    • Yao Xiao
    • Yanting Wu
    • Yun Liu
    • Zhiqing Song
    • Wenfeng Gao
    • Jing Zhang
    • Jingling Yang
    • Yuguo Zhang
    • Tuankui Guo
    • Furong Dai
    • Zhigang Sun
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, The 4th Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia 014040, P.R. China, Department of Hepatobiliary and Pancreatic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China, Department of General Surgery, The Third Clinical Medical School of Inner Mongolia Medical University (Baogang Hospital of Inner Mongolia), Baotou, Inner Mongolia 014010, P.R. China, Department of Neurosurgery, Baotou Eighth Hospital, Baotou, Inner Mongolia 014040, P.R. China
  • Pages: 1587-1595
    |
    Published online on: September 27, 2016
       https://doi.org/10.3892/ijmm.2016.2754
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Abstract

MicroRNAs (miRNAs or miRs) have been found to participate in the development and malignant progression of human cancers by negatively mediating the expression of their target genes. Recently, miR‑33b has been reported to be involved in multiple types of human cancer, including hepatocellular carcinoma (HCC). However, the underlying regulatory mechanisms of miR‑33b in HCC cell growth and metastasis remain largely unclear. In the present study, RT-qPCR revealed that miR‑33b was significantly downregulated in HCC tissues compared to their matched adjacent normal tissues. Moreover, the miR‑33b level was significantly lower in advanced-stage HCC (stages T3-T4) compared to early-stage HCC (stages T1-T2). Furthermore, it was also downregulated in the HCC cell lines, LH86, HepG2, LMH and PLHC-1, when compared with the THLE-3 normal human liver cells. We further demonstrated that the overexpression of miR‑33b led to a significant decrease in the proliferation, migration and invasion of HepG2 and LH86 cells. Luciferase reporter assay identified Sal-like protein 4 (SALL4) as a target gene of miR‑33b, and its protein expression was negatively regulated by miR‑33b in HepG2 and LH86 cells. Moreover, the restoration of SALL4 expression markedly reversed the inhibitory effect of miR‑33b overexpression on the proliferation, migration and invasion of HepG2 and LH86 cells, indicating that SALL4 is involved in miR‑33b-mediated malignant phenotypes of HCC cells. Furthermore, we found that SALL4 was significantly upregulated in HCC tissues compared to their matched adjacent normal tissues, and its increased expression was significantly associated with the advanced malignancy of HCC. Moreover, SALL4 was also upregulated in HCC cell lines compared to the THLE-3 normal human liver cells. Finally, we found that the SALL4 expression inversely correlated with the miR‑33b level in HCC tissues. On the whole, the findings of our study demonstrate that miR‑33b suppresses the proliferation and metastasis of HCC cells through the inhibition of SALL4 expression. Therefore, miR‑33b/SALL4 may become a potential therapeutic target for the treatment of HCC.
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1 

Siegel R, Naishadham D and Jemal A: Cancer statistics, 2013. CA Cancer J Clin. 63:11–30. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Zhu AX: Molecularly targeted therapy for advanced hepatocellular carcinoma in 2012: Current status and future perspectives. Semin Oncol. 39:493–502. 2012. View Article : Google Scholar : PubMed/NCBI

3 

Dongiovanni P, Romeo S and Valenti L: Hepatocellular carcinoma in nonalcoholic fatty liver: Role of environmental and genetic factors. World J Gastroenterol. 20:12945–12955. 2014. View Article : Google Scholar : PubMed/NCBI

4 

Su CH, Lin Y and Cai L: Genetic factors, viral infection, other factors and liver cancer: An update on current progress. Asian Pac J Cancer Prev. 14:4953–4960. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Chen C and Wang G: Mechanisms of hepatocellular carcinoma and challenges and opportunities for molecular targeted therapy. World J Hepatol. 7:1964–1970. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Chen X, Vega VB and Ng HH: Transcriptional regulatory networks in embryonic stem cells. Cold Spring Harb Symp Quant Biol. 73:203–209. 2008. View Article : Google Scholar : PubMed/NCBI

7 

Zhang X, Yuan X, Zhu W, Qian H and Xu W: SALL4: An emerging cancer biomarker and target. Cancer Lett. 357:55–62. 2015. View Article : Google Scholar

8 

Oishi N, Yamashita T and Kaneko S: Molecular biology of liver cancer stem cells. Liver Cancer. 3:71–84. 2014. View Article : Google Scholar : PubMed/NCBI

9 

Oikawa T, Kamiya A, Zeniya M, Chikada H, Hyuck AD, Yamazaki Y, Wauthier E, Tajiri H, Miller LD, Wang XW, et al: Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers. Hepatology. 57:1469–1483. 2013. View Article : Google Scholar

10 

Shikauchi Y, Saiura A, Kubo T, Niwa Y, Yamamoto J, Murase Y and Yoshikawa H: SALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinoma. Mol Cell Biol. 29:1944–1958. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Zeng SS, Yamashita T, Kondo M, Nio K, Hayashi T, Hara Y, Nomura Y, Yoshida M, Hayashi T, Oishi N, et al: The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma. J Hepatol. 60:127–134. 2014. View Article : Google Scholar

12 

Han SX, Wang JL, Guo XJ, He CC, Ying X, Ma JL, Zhang YY, Zhao Q and Zhu Q: Serum SALL4 is a novel prognosis biomarker with tumor recurrence and poor survival of patients in hepatocellular carcinoma. J Immunol Res. 2014:2623852014. View Article : Google Scholar : PubMed/NCBI

13 

Ambros V: The functions of animal microRNAs. Nature. 431:350–355. 2004. View Article : Google Scholar : PubMed/NCBI

14 

Tessitore A, Cicciarelli G, Del Vecchio F, Gaggiano A, Verzella D, Fischietti M, Vecchiotti D, Capece D, Zazzeroni F and Alesse E: MicroRNAs in the DNA Damage/Repair Network and Cancer. Int J Genomics. 2014:8202482014. View Article : Google Scholar : PubMed/NCBI

15 

Esquela-Kerscher A and Slack FJ: Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer. 6:259–269. 2006. View Article : Google Scholar : PubMed/NCBI

16 

Coulouarn C, Factor VM, Andersen JB, Durkin ME and Thorgeirsson SS: Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene. 28:3526–3536. 2009. View Article : Google Scholar : PubMed/NCBI

17 

Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I and Inazawa J: miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis. 31:766–776. 2010. View Article : Google Scholar

18 

Wang W, Zhao LJ, Tan YX, Ren H and Qi ZT: MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma. Carcinogenesis. 33:1113–1120. 2012. View Article : Google Scholar : PubMed/NCBI

19 

Yin W, Zhao Y, Ji YJ, Tong LP, Liu Y, He SX and Wang AQ: Serum/plasma microRNAs as biomarkers for HBV-related hepatocellular carcinoma in China. BioMed Res Int. 2015:9651852015. View Article : Google Scholar : PubMed/NCBI

20 

Fang Y, Feng Y, Wu T, Srinivas S, Yang W, Fan J, Yang C and Wang S: Aflatoxin B1 negatively regulates Wnt/β-catenin signaling pathway through activating miR-33a. PLoS One. 8:e730042013. View Article : Google Scholar

21 

Antaramian A, González-Gallardo A, García-Ugalde C, Portillo W and Paredes RG: Steroid Receptors and Aromatase Gene Expression in Different Brain Areas of Copulating and Sexually Sluggish Male Rats. J Sex Med. 12:2267–2275. 2015. View Article : Google Scholar : PubMed/NCBI

22 

Rottiers V and Näär AM: MicroRNAs in metabolism and metabolic disorders. Nat Rev Mol Cell Biol. 13:239–250. 2012. View Article : Google Scholar : PubMed/NCBI

23 

Lv SQ, Kim YH, Giulio F, Shalaby T, Nobusawa S, Yang H, Zhou Z, Grotzer M and Ohgaki H: Genetic alterations in microRNAs in medulloblastomas. Brain Pathol. 22:230–239. 2012. View Article : Google Scholar

24 

Miyachi K, Sawada Y, Shida Y, Sugawara A and Hisatomi H: Lipogenic gene expression profile in patients with gastric cancer. Mol Clin Oncol. 1:825–827. 2013.

25 

Hao M, Zang M, Wendlandt E, Xu Y, An G, Gong D, Li F, Qi F, Zhang, Yang Y, et al: Low serum miR-19a expression as a novel poor prognostic indicator in multiple myeloma. Int J Cancer. 136:1835–1844. 2015. View Article : Google Scholar :

26 

Li F, Hao M, Feng X, Zang M, Qin Y, Yi S, Li Z, Xu Y, Zhou L, Sui W, et al: Downregulated miR-33b is a novel predictor associated with disease progression and poor prognosis in multiple myeloma. Leuk Res. 39:793–799. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Yoshitaka T, Kawai A, Miyaki S, Numoto K, Kikuta K, Ozaki T, Lotz M and Asahara H: Analysis of microRNAs expressions in chondrosarcoma. J Orthop Res. 31:1992–1998. 2013. View Article : Google Scholar : PubMed/NCBI

28 

Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF, Lee S, et al: Oncofetal gene SALL4 in aggressive hepatocellular carcinoma. N Engl J Med. 368:2266–2276. 2013. View Article : Google Scholar : PubMed/NCBI

29 

Park H, Lee H, Seo AN, Cho JY, Choi YR, Yoon YS, Han HS, Park YN and Kim H: SALL4 Expression in Hepatocellular Carcinomas Is Associated with EpCAM-Positivity and a Poor Prognosis. J Pathol Transl Med. 49:373–381. 2015. View Article : Google Scholar : PubMed/NCBI

30 

Shibahara J, Ando S, Hayashi A, Sakamoto Y, Hesegawa K, Kokudo N and Fukayama M: Clinicopathologic characteristics of SALL4-immunopositive hepatocellular carcinoma. Springerplus. 3:7212014. View Article : Google Scholar : PubMed/NCBI

31 

Lin Y, Liu AY, Fan C, Zheng H, Li Y, Zhang C, Wu S, Yu D, Huang Z, Liu F, et al: MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1. Sci Rep. 5:99952015. View Article : Google Scholar : PubMed/NCBI

32 

Zhang P, Huang C, Fu C, Tian Y, Hu Y, Wang B, Strasner A, Song Y and Song E: Cordycepin (3′-deoxyadenosine) suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b. Oncotarget. 6:9834–9853. 2015. View Article : Google Scholar :

33 

Lee SA, Ho C, Roy R, Kosinski C, Patil MA, Tward AD, Fridlyand J and Chen X: Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer. Hepatology. 47:1200–1210. 2008. View Article : Google Scholar : PubMed/NCBI

34 

Wang C, Delogu S, Ho C, Lee SA, Gui B, Jiang L, Ladu S, Cigliano A, Dombrowski F, Evert M, et al: Inactivation of Spry2 accelerates AKT-driven hepatocarcinogenesis via activation of MAPK and PKM2 pathways. J Hepatol. 57:577–583. 2012. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Tian Q, Xiao Y, Wu Y, Liu Y, Song Z, Gao W, Zhang J, Yang J, Zhang Y, Guo T, Guo T, et al: MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003. Int J Mol Med 38: 1587-1595, 2016.
APA
Tian, Q., Xiao, Y., Wu, Y., Liu, Y., Song, Z., Gao, W. ... Sun, Z. (2016). MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003. International Journal of Molecular Medicine, 38, 1587-1595. https://doi.org/10.3892/ijmm.2016.2754
MLA
Tian, Q., Xiao, Y., Wu, Y., Liu, Y., Song, Z., Gao, W., Zhang, J., Yang, J., Zhang, Y., Guo, T., Dai, F., Sun, Z."MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003". International Journal of Molecular Medicine 38.5 (2016): 1587-1595.
Chicago
Tian, Q., Xiao, Y., Wu, Y., Liu, Y., Song, Z., Gao, W., Zhang, J., Yang, J., Zhang, Y., Guo, T., Dai, F., Sun, Z."MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003". International Journal of Molecular Medicine 38, no. 5 (2016): 1587-1595. https://doi.org/10.3892/ijmm.2016.2754
Copy and paste a formatted citation
x
Spandidos Publications style
Tian Q, Xiao Y, Wu Y, Liu Y, Song Z, Gao W, Zhang J, Yang J, Zhang Y, Guo T, Guo T, et al: MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003. Int J Mol Med 38: 1587-1595, 2016.
APA
Tian, Q., Xiao, Y., Wu, Y., Liu, Y., Song, Z., Gao, W. ... Sun, Z. (2016). MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003. International Journal of Molecular Medicine, 38, 1587-1595. https://doi.org/10.3892/ijmm.2016.2754
MLA
Tian, Q., Xiao, Y., Wu, Y., Liu, Y., Song, Z., Gao, W., Zhang, J., Yang, J., Zhang, Y., Guo, T., Dai, F., Sun, Z."MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003". International Journal of Molecular Medicine 38.5 (2016): 1587-1595.
Chicago
Tian, Q., Xiao, Y., Wu, Y., Liu, Y., Song, Z., Gao, W., Zhang, J., Yang, J., Zhang, Y., Guo, T., Dai, F., Sun, Z."MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression Retraction in /10.3892/ijmm.2021.5003". International Journal of Molecular Medicine 38, no. 5 (2016): 1587-1595. https://doi.org/10.3892/ijmm.2016.2754
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