|
1
|
Tzioupis C and Giannoudis PV: Prevalence
of long-bone non-unions. Injury. 38(Suppl 2): S3–S9. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Einhorn TA and Gerstenfeld LC: Fracture
healing: mechanisms and interventions. Nat Rev Rheumatol. 11:45–54.
2015. View Article : Google Scholar :
|
|
3
|
Dimitriou R, Kanakaris N, Soucacos PN and
Giannoudis PV: Genetic predisposition to non-union: evidence today.
Injury. 44(Suppl 1): S50–S53. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Copuroglu C, Calori GM and Giannoudis PV:
Fracture non-union: Who is at risk? Injury. 44:1379–1382. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
He L and Hannon GJ: MicroRNAs: Small RNAs
with a big role in gene regulation. Nat Rev Genet. 5:522–531. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Calin GA and Croce CM: MicroRNA signatures
in human cancers. Nat Rev Cancer. 6:857–866. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lim LP, Glasner ME, Yekta S, Burge CB and
Bartel DP: Vertebrate microRNA genes. Science. 299:15402003.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kozomara A and Griffiths-Jones S: miRBase:
Integrating microRNA annotation and deep-sequencing data. Nucleic
Acids Res. 39:D152–D157. 2011. View Article : Google Scholar :
|
|
9
|
Friedländer MR, Lizano E, Houben AJ,
Bezdan D, Báñez-Coronel M, Kudla G, Mateu-Huertas E, Kagerbauer B,
González J, Chen KC, et al: Evidence for the biogenesis of more
than 1,000 novel human microRNAs. Genome Biol. 15:R572014.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Xu N, Li Z, Yu Z, Yan F, Liu Y, Lu X and
Yang W: MicroRNA-33b suppresses migration and invasion by targeting
c-Myc in osteosarcoma cells. PLoS One. 9:e1153002014. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
He C, Xiong J, Xu X, Lu W, Liu L, Xiao D
and Wang D: Functional elucidation of MiR-34 in osteosarcoma cells
and primary tumor samples. Biochem Biophys Res Commun. 388:35–40.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Zhuo W, Ge W, Meng G, Jia S, Zhou X and
Liu J: MicroRNA-20a promotes the proliferation and cell cycle of
human osteosarcoma cells by suppressing early growth response 2
expression. Mol Med Rep. 12:4989–4994. 2015.PubMed/NCBI
|
|
13
|
Mori F, Sacconi A, Canu V, Ganci F,
Novello M, Anelli V, Covello R, Ferraresi V, Muti P, Biagini R, et
al: miR-181c associates with tumor relapse of high grade
osteosarcoma. Oncotarget. 6:13946–13961. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Salah Z, Arafeh R, Maximov V, Galasso M,
Khawaled S, Abou-Sharieha S, Volinia S, Jones KB, Croce CM and
Aqeilan RI: miR-27a and miR-27a* contribute to metastatic
properties of osteosarcoma cells. Oncotarget. 6:4920–4935. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Mu Y, Zhang H, Che L and Li K: Clinical
significance of microRNA-183/Ezrin axis in judging the prognosis of
patients with osteosarcoma. Med Oncol. 31:8212014. View Article : Google Scholar
|
|
16
|
Kawano M, Tanaka K, Itonaga I, Ikeda S,
Iwasaki T and Tsumura H: microRNA-93 promotes cell proliferation
via targeting of PTEN in Osteosarcoma cells. J Exp Clin Cancer Res.
34:762015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Qu F, Li CB, Yuan BT, Qi W, Li HL, Shen
XZ, Zhao G, Wang JT and Liu YJ: MicroRNA-26a induces osteosarcoma
cell growth and metastasis via the Wnt/β-catenin pathway. Oncol
Lett. 11:1592–1596. 2016.PubMed/NCBI
|
|
18
|
Yuan J, Lang J, Liu C, Zhou K, Chen L and
Liu Y: The expression and function of miRNA-451 in osteosarcoma.
Med Oncol. 32:3242015. View Article : Google Scholar
|
|
19
|
Zhang C, Yao C, Li H, Wang G and He X:
Serum levels of microRNA-133b and microRNA-206 expression predict
prognosis in patients with osteosarcoma. Int J Clin Exp Pathol.
7:4194–4203. 2014.PubMed/NCBI
|
|
20
|
Zhang C, Yao C, Li H, Wang G and He X:
Combined elevation of microRNA-196a and microRNA-196b in sera
predicts unfavorable prognosis in patients with osteosarcomas. Int
J Mol Sci. 15:6544–6555. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Liua XD, Caia F, Liu L, Zhang Y and Yang
AL: microRNA-210 is involved in the regulation of postmenopausal
osteoporosis through promotion of VEGF expression and osteoblast
differentiation. Biol Chem. 396:339–347. 2015.
|
|
22
|
Jia J, Feng X, Xu W, Yang S, Zhang Q, Liu
X, Feng Y and Dai Z: miR-17-5p modulates osteoblastic
differentiation and cell proliferation by targeting SMAD7 in
non-traumatic osteonecrosis. Exp Mol Med. 46:e1072014. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhao B, Yu Q, Li H, Guo X and He X:
Characterization of microRNA expression profiles in patients with
intervertebral disc degeneration. Int J Mol Med. 33:43–50.
2014.
|
|
24
|
Yu X, Li Z, Shen J, Wu WK, Liang J, Weng X
and Qiu G: MicroRNA-10b promotes nucleus pulposus cell
proliferation through RhoC-Akt pathway by targeting HOXD10 in
intervetebral disc degeneration. PLoS One. 8:e830802013. View Article : Google Scholar :
|
|
25
|
Miyaki S, Sato T, Inoue A, Otsuki S, Ito
Y, Yokoyama S, Kato Y, Takemoto F, Nakasa T, Yamashita S, et al:
MicroRNA-140 plays dual roles in both cartilage development and
homeostasis. Genes Dev. 24:1173–1185. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Nakasa T, Shibuya H, Nagata Y, Niimoto T
and Ochi M: The inhibitory effect of microRNA-146a expression on
bone destruction in collagen-induced arthritis. Arthritis Rheum.
63:1582–1590. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lee YJ, Jeong JK, Seol JW, Xue M, Jackson
C and Park SY: Activated protein C differentially regulates both
viability and differentiation of osteoblasts mediated by
bisphosphonates. Exp Mol Med. 45:e92013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Brinker MR and Bailey DE Jr: Fracture
healing in tibia fractures with an associated vascular injury. J
Trauma. 42:11–19. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Santavirta S, Konttinen YT, Nordström D,
Mäkelä A, Sorsa T, Hukkanen M and Rokkanen P: Immunologic studies
of nonunited fractures. Acta Orthop Scand. 63:579–586. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Moghaddam A, Elleser C, Biglari B,
Wentzensen A and Zimmermann G: Clinical application of BMP 7 in
long bone non-unions. Arch Orthop Trauma Surg. 130:71–76. 2010.
View Article : Google Scholar
|
|
31
|
Fayaz HC, Giannoudis PV, Vrahas MS, Smith
RM, Moran C, Pape HC, Krettek C and Jupiter JB: The role of stem
cells in fracture healing and nonunion. Int Orthop. 35:1587–1597.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Oskowitz AZ, Lu J, Penfornis P, Ylostalo
J, McBride J, Flemington EK, Prockop DJ and Pochampally R: Human
multipotent stromal cells from bone marrow and microRNA: Regulation
of differentiation and leukemia inhibitory factor expression. Proc
Natl Acad Sci USA. 105:18372–18377. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wei J, Shi Y, Zheng L, Zhou B, Inose H,
Wang J, Guo XE, Grosschedl R and Karsenty G: miR-34s inhibit
osteoblast proliferation and differentiation in the mouse by
targeting SATB2. J Cell Biol. 197:509–521. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zeng Y, Qu X, Li H, Huang S, Wang S, Xu Q,
Lin R, Han Q, Li J and Zhao RC: MicroRNA-100 regulates osteogenic
differentiation of human adipose-derived mesenchymal stem cells by
targeting BMPR2. FEBS Lett. 586:2375–2381. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Wang X, Guo B, Li Q, Peng J, Yang Z, Wang
A, Li D, Hou Z, Lv K, Kan G, et al: miR-214 targets ATF4 to inhibit
bone formation. Nat Med. 19:93–100. 2013. View Article : Google Scholar
|
|
36
|
Yang L, Cheng P, Chen C, He HB, Xie GQ,
Zhou HD, Xie H, Wu XP and Luo XH: miR-93/Sp7 function loop mediates
osteoblast mineralization. J Bone Miner Res. 27:1598–1606. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Huang S, Wang S, Bian C, Yang Z, Zhou H,
Zeng Y, Li H, Han Q and Zhao RC: Upregulation of miR-22 promotes
osteogenic differentiation and inhibits adipogenic differentiation
of human adipose tissue-derived mesenchymal stem cells by
repressing HDAC6 protein expression. Stem Cells Dev. 21:2531–2540.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Li H, Xie H, Liu W, Hu R, Huang B, Tan YF,
Xu K, Sheng ZF, Zhou HD, Wu XP and Luo XH: A novel microRNA
targeting HDAC5 regulates osteoblast differentiation in mice and
contributes to primary osteoporosis in humans. J Clin Invest.
119:3666–3677. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
39
|
Cui L, Qi Y, Li H, Ge Y, Zhao K, Qi X, Guo
X, Shi Z, Zhou M, Zhu B, et al: Serum microRNA expression profile
distinguishes enterovirus 71 and coxsackievirus 16 infections in
patients with hand-foot-and-mouth disease. PLoS One. 6:e270712011.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Li A, Yu J, Kim H, Wolfgang CL, Canto MI,
Hruban RH and Goggins M: MicroRNA array analysis finds elevated
serum miR-1290 accurately distinguishes patients with low-stage
pancreatic cancer from healthy and disease controls. Clin Cancer
Res. 19:3600–3610. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Stratz C, Nührenberg T, Fiebich BL, Amann
M, Kumar A, Binder H, Hoffmann I, Valina C, Hochholzer W, Trenk D,
et al: Controlled type II diabetes mellitus has no major influence
on platelet micro-RNA expression. Results from micro-array
profiling in a cohort of 60 patients. Thromb Haemost. 111:902–911.
2014. View Article : Google Scholar
|
|
42
|
Zhang Y, Xie RL, Croce CM, Stein JL, Lian
JB, van Wijnen AJ and Stein GS: A program of microRNAs controls
osteogenic lineage progression by targeting transcription factor
Runx2. Proc Natl Acad Sci USA. 108:9863–9868. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Li Z, Hassan MQ, Volinia S, van Wijnen AJ,
Stein JL, Croce CM, Lian JB and Stein GS: A microRNA signature for
a BMP2-induced osteoblast lineage commitment program. Proc Natl
Acad Sci USA. 105:13906–13911. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Li Z, Hassan MQ, Jafferji M, Aqeilan RI,
Garzon R, Croce CM, van Wijnen AJ, Stein JL, Stein GS and Lian JB:
Biological functions of miR-29b contribute to positive regulation
of osteoblast differentiation. J Biol Chem. 284:15676–15684. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Hassan MQ, Gordon JA, Beloti MM, Croce CM,
van Wijnen AJ, Stein JL, Stein GS and Lian JB: A network connecting
Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the
osteoblast differentiation program. Proc Natl Acad Sci USA.
107:19879–19884. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Hassan MQ, Maeda Y, Taipaleenmaki H, Zhang
W, Jafferji M, Gordon JA, Li Z, Croce CM, van Wijnen AJ, Stein JL,
et al: miR-218 directs a Wnt signaling circuit to promote
differentiation of osteoblasts and osteomimicry of metastatic
cancer cells. J Biol Chem. 287:42084–42092. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Zuo B, Zhu J, Li J, Wang C, Zhao X, Cai G,
Li Z, Peng J, Wang P, Shen C, et al: microRNA-103a functions as a
mechno-sensitive microRNA to inhibit bone formation through
targeting Runx2. J Bone Miner Res. 30:330–245. 2015. View Article : Google Scholar
|
