|
1
|
Singer M, Deutschman CS, Seymour CW,
Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche
JD, Coopersmith CM, et al: The Third International Consensus
Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA.
315:801–810. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
O'Brien JM Jr, Ali NA, Aberegg SK and
Abraham E: Sepsis. Am J Med. 120:1012–1022. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Gabay C, Lamacchia C and Palmer G: IL-1
pathways in inflammation and human diseases. Nat Rev Rheumatol.
6:232–241. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Cohen J: The immunopathogenesis of sepsis.
Nature. 420:885–891. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Pinheiro da Silva F and Nizet V: Cell
death during sepsis: Integration of disintegration in the
inflammatory response to overwhelming infection. Apoptosis.
14:509–521. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Hotchkiss RS and Nicholson DW: Apoptosis
and caspases regulate death and inflammation in sepsis. Nat Rev
Immunol. 6:813–822. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Sarkar A, Hall MW, Exline M, Hart J, Knatz
N, Gatson NT and Wewers MD: Caspase-1 regulates Escherichia coli
sepsis and splenic B cell apoptosis independently of interleukin-1β
and interleukin-18. Am J Respir Crit Care Med. 174:1003–1010. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hu Z, Murakami T, Suzuki K, Tamura H,
Reich J, Kuwahara-Arai K, Iba T and Nagaoka I: Antimicrobial
cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages
and improves the survival of polybacterial septic mice. Int
Immunol. 28:245–253. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Mantovani A, Cassatella MA, Costantini C
and Jaillon S: Neutrophils in the activation and regulation of
innate and adaptive immunity. Nat Rev Immunol. 11:519–531. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Nathan C: Neutrophils and immunity:
Challenges and opportunities. Nat Rev Immunol. 6:173–182. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Camicia G, Pozner R and de Larrañaga G:
Neutrophil extracellular traps in sepsis. Shock. 42:286–294. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Remijsen Q, Kuijpers TW, Wirawan E,
Lippens S, Vandenabeele P and Vanden Berghe T: Dying for a cause:
NETosis, mechanisms behind an antimicrobial cell death modality.
Cell Death Differ. 18:581–588. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
McDonald B, Urrutia R, Yipp BG, Jenne CN
and Kubes P: Intravascular neutrophil extracellular traps capture
bacteria from the bloodstream during sepsis. Cell Host Microbe.
12:324–333. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Urban CF, Ermert D, Schmid M, Abu-Abed U,
Goosmann C, Nacken W, Brinkmann V, Jungblut PR and Zychlinsky A:
Neutrophil extracellular traps contain calprotectin, a cytosolic
protein complex involved in host defense against Candida albicans.
PLoS Pathog. 5:e10006392009. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Saffarzadeh M, Juenemann C, Queisser MA,
Lochnit G, Barreto G, Galuska SP, Lohmeyer J and Preissner KT:
Neutrophil extracellular traps directly induce epithelial and
endothelial cell death: A predominant role of histones. PLoS One.
7:e323662012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Alfaidi M, Wilson H, Daigneault M, Burnett
A, Ridger V, Chamberlain J and Francis S: Neutrophil elastase
promotes interleukin-1β secretion from human coronary endothelium.
J Biol Chem. 290:24067–24078. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Xu J, Zhang X, Monestier M, Esmon L and
Esmon CT: Extracellular histones are mediators of death through
TLR2 and TLR4 in mouse fatal liver injury. J Immunol.
187:2626–2631. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Xu J, Zhang X, Pelayo R, Monestier M,
Ammollo CT, Semeraro F, Taylor FB, Esmon L, Lupu F and Esmon CT:
Extracellular histones are major mediators of death in sepsis. Nat
Med. 15:1318–1321. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Gould TJ, Vu TT, Swystun LL, Dwivedi DJ,
Mai SH, Weitz JI and Liaw PC: Neutrophil extracellular traps
promote thrombin generation through platelet-dependent and
platelet-independent mechanisms. Arterioscler Thromb Vasc Biol.
34:1977–1984. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Braian C, Hogea V and Stendahl O:
Mycobacterium tuberculosis-induced neutrophil extracellular traps
activate human macrophages. J Innate Immun. 5:591–602. 2013.
View Article : Google Scholar
|
|
21
|
Cools-Lartigue J, Spicer J, McDonald B,
Gowing S, Chow S, Giannias B, Bourdeau F, Kubes P and Ferri L:
Neutrophil extracellular traps sequester circulating tumor cells
and promote metastasis. J Clin Invest. 123:3446–3458. 2013.
View Article : Google Scholar :
|
|
22
|
Farrera C and Fadeel B: Macrophage
clearance of neutrophil extracellular traps is a silent process. J
Immunol. 191:2647–2656. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Luo L, Zhang S, Wang Y, Rahman M, Syk I,
Zhang E and Thorlacius H: Proinflammatory role of neutrophil
extracellular traps in abdominal sepsis. Am J Physiol Lung Cell Mol
Physiol. 307:L586–L596. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Meng W, Paunel-Görgülü A, Flohé S,
Hoffmann A, Witte I, MacKenzie C, Baldus SE, Windolf J and Lögters
TT: Depletion of neutrophil extracellular traps in vivo results in
hypersusceptibility to polymicrobial sepsis in mice. Crit Care.
16:R1372012. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Mai SH, Khan M, Dwivedi DJ, Ross CA, Zhou
J, Gould TJ, Gross PL, Weitz JI, Fox-Robichaud AE and Liaw PC;
Canadian Critical Care Translational Biology Group: Delayed but not
early treatment with DNase reduces organ damage and improves
outcome in a murine model of sepsis. Shock. 44:166–172. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Karmakar M, Sun Y, Hise AG, Rietsch A and
Pearlman E: Cutting edge: IL-1β processing during Pseudomonas
aeruginosa infection is mediated by neutrophil serine proteases and
is independent of NLRC4 and caspase-1. J Immunol. 189:4231–4235.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Casey LC, Balk RA and Bone RC: Plasma
cytokine and endotoxin levels correlate with survival in patients
with the sepsis syndrome. Ann Intern Med. 119:771–778. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Miao EA, Rajan JV and Aderem A:
Caspase-1-induced pyroptotic cell death. Immunol Rev. 243:206–214.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Bergsbaken T, Fink SL and Cookson BT:
Pyroptosis: Host cell death and inflammation. Nat Rev Microbiol.
7:99–109. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bryant C and Fitzgerald KA: Molecular
mechanisms involved in inflammasome activation. Trends Cell Biol.
19:455–464. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Antonopoulos C, Russo HM, El Sanadi C,
Martin BN, Li X, Kaiser WJ, Mocarski ES and Dubyak GR: Caspase-8 as
an effector and regulator of NLRP3 inflammasome signaling. J Biol
Chem. 290:20167–20184. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Maelfait J, Vercammen E, Janssens S,
Schotte P, Haegman M, Magez S and Beyaert R: Stimulation of
Toll-like receptor 3 and 4 induces interleukin-1β maturation by
caspase-8. J Exp Med. 205:1967–1973. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Vince JE, Wong WW, Gentle I, Lawlor KE,
Allam R, O'Reilly L, Mason K, Gross O, Ma S, Guarda G, et al:
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent
interleukin-1 activation. Immunity. 36:215–227. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Shenderov K, Riteau N, Yip R, Mayer-Barber
KD, Oland S, Hieny S, Fitzgerald P, Oberst A, Dillon CP, Green DR,
et al: Cutting edge: Endoplasmic reticulum stress licenses
macrophages to produce mature IL-1β in response to TLR4 stimulation
through a caspase-8- and TRIF-dependent pathway. J Immunol.
192:2029–2033. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Harijith A, Ebenezer DL and Natarajan V:
Reactive oxygen species at the crossroads of inflammasome and
inflammation. Front Physiol. 5:3522014. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
El Kebir D and Filep JG: Targeting
neutrophil apoptosis for enhancing the resolution of inflammation.
Cells. 2:330–348. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Hu Z, Murakami T, Suzuki K, Tamura H,
Kuwahara-Arai K, Iba T and Nagaoka I: Antimicrobial cathelicidin
peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of
macrophages by dual mechanism. PLoS One. 9:e857652014. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Mao K, Chen S, Chen M, Ma Y, Wang Y, Huang
B, He Z, Zeng Y, Hu Y, Sun S, et al: Nitric oxide suppresses NLRP3
inflammasome activation and protects against LPS-induced septic
shock. Cell Res. 23:201–212. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Muruve DA, Pétrilli V, Zaiss AK, White LR,
Clark SA, Ross PJ, Parks RJ and Tschopp J: The inflammasome
recognizes cytosolic microbial and host DNA and triggers an innate
immune response. Nature. 452:103–107. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Sagulenko V, Thygesen SJ, Sester DP, Idris
A, Cridland JA, Vajjhala PR, Roberts TL, Schroder K, Vince JE, Hill
JM, et al: AIM2 and NLRP3 inflammasomes activate both apoptotic and
pyroptotic death pathways via ASC. Cell Death Differ. 20:1149–1160.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Anand RJ, Kohler JW, Cavallo JA, Li J,
Dubowski T and Hackam DJ: Toll-like receptor 4 plays a role in
macrophage phagocytosis during peritoneal sepsis. J Pediatr Surg.
42:927–932; discussion 933. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Beyer C and Pisetsky DS: Modeling nuclear
molecule release during in vitro cell death. Autoimmunity.
46:298–301. 2013. View Article : Google Scholar
|
|
43
|
Meng W, Paunel-Görgülü A, Flohé S, Witte
I, Schädel-Höpfner M, Windolf J and Lögters TT: Deoxyribonuclease
is a potential counter regulator of aberrant neutrophil
extracellular traps formation after major trauma. Mediators
Inflamm. 2012:1495602012. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Czaikoski PG, Mota JM, Nascimento DC,
Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL,
Barroso-Sousa R, Souto FO, et al: Neutrophil extracellular traps
induce organ damage during experimental and clinical sepsis. PLoS
One. 11:e01481422016. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Tanaka K, Koike Y, Shimura T, Okigami M,
Ide S, Toiyama Y, Okugawa Y, Inoue Y, Araki T, Uchida K, et al: In
vivo characterization of neutrophil extracellular traps in various
organs of a murine sepsis model. PLoS One. 9:e11–1888. 2014.
View Article : Google Scholar
|
|
46
|
Pham CT: Neutrophil serine proteases:
Specific regulators of inflammation. Nat Rev Immunol. 6:541–550.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Schauer C, Janko C, Munoz LE, Zhao Y,
Kienhöfer D, Frey B, Lell M, Manger B, Rech J, Naschberger E, et
al: Aggregated neutrophil extracellular traps limit inflammation by
degrading cytokines and chemokines. Nat Med. 20:511–517. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Netea MG, Simon A, van de Veerdonk F,
Kullberg BJ, Van der Meer JW and Joosten LA: IL-1β processing in
host defense: Beyond the inflammasomes. PLoS Pathog.
6:e10006612010. View Article : Google Scholar
|
|
49
|
Thomas MP, Whangbo J, McCrossan G, Deutsch
AJ, Martinod K, Walch M and Lieberman J: Leukocyte protease binding
to nucleic acids promotes nuclear localization and cleavage of
nucleic acid binding proteins. J Immunol. 192:5390–5397. 2014.
View Article : Google Scholar : PubMed/NCBI
|
