|
1
|
Tripp MK, Watson M, Balk SJ, Swetter SM
and Gershenwald JE: State of the science on prevention and
screening to reduce melanoma incidence and mortality: The time is
now. CA Cancer J Clin. 66:460–480. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Rambow F, Marine JC and Goding CR:
Melanoma plasticity and phenotypic diversity: Therapeutic barriers
and opportunities. Genes Dev. 33:1295–1318. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Klemen ND, Wang M, Feingold PL, Cooper K,
Pavri SN, Han D, Detterbeck FC, Boffa DJ, Khan SA, Olino K, et al:
Patterns of failure after immunotherapy with checkpoint inhibitors
predict durable progression-free survival after local therapy for
metastatic melanoma. J Immunother Cancer. 7:1962019. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Li F and Simon MC: Cancer cells don't live
alone: Metabolic communication within tumor microenvironments. Dev
Cell. 54:183–195. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hass R, von der Ohe J and Ungefroren H:
Impact of the tumor microenvironment on tumor heterogeneity and
consequences for cancer cell plasticity and stemness. Cancers
(Basel). 12:37162020. View Article : Google Scholar
|
|
6
|
Qin S, Jiang J, Lu Y, Nice EC, Huang C,
Zhang J and He W: Emerging role of tumor cell plasticity in
modifying therapeutic response. Signal Transduct Target Ther.
5:1–36. 2020. View Article : Google Scholar
|
|
7
|
Maishi N and Hida K: Tumor endothelial
cells accelerate tumor metastasis. Cancer Sci. 108:1921–1926. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Howard JD, Moriarty WF, Park J, Riedy K,
Panova IP, Chung CH, Suh KY, Levchenko A and Alani RM: Notch
signaling mediates melanoma-endothelial cell communication and
melanoma cell migration. Pigment Cell Melanoma Res. 26:697–707.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Long X, Ye Y, Zhang L, Liu P, Yu W, Wei F,
Ren X and Yu J: IL-8, a novel messenger to cross-link inflammation
and tumor emt via autocrine and paracrine pathways (Review). Int J
Oncol. 48:5–12. 2016. View Article : Google Scholar
|
|
10
|
Weinberg F, Ramnath N and Nagrath D:
Reactive oxygen species in the tumor microenvironment: An overview.
Cancers (Basel). 11:11912019. View Article : Google Scholar
|
|
11
|
Tasdogan A, Faubert B, Ramesh V,
Ubellacker JM, Shen B, Solmonson A, Murphy MM, Gu Z, Gu W, Martin
M, et al: Metabolic heterogeneity confers differences in melanoma
metastatic potential. Nature. 577:115–120. 2020. View Article : Google Scholar
|
|
12
|
Barrera G: Oxidative stress and lipid
peroxidation products in cancer progression and therapy. ISRN
Oncol. 2012:1372892012.PubMed/NCBI
|
|
13
|
Luo Y, Dallaglio K, Chen Y, Robinson WA,
Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris
DA, et al: ALDH1A isozymes are markers of human melanoma stem cells
and potential therapeutic targets. Stem Cells. 30:2100–2113. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ma I and Allan AL: The role of human
aldehyde dehydrogenase in normal and cancer stem cells. Stem Cell
Rev Rep. 7:292–306. 2011. View Article : Google Scholar
|
|
15
|
Moreb JS, Baker HV, Chang LJ, Amaya M,
Lopez MC, Ostmark B and Chou W: ALDH isozymes downregulation
affects cell growth, cell motility and gene expression in lung
cancer cells. Mol Cancer. 7:872008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Charafe-Jauffret E, Ginestier C, Iovino F,
Tarpin C, Diebel M, Esterni B, Houvenaeghel G, Extra JM, Bertucci
F, Jacquemier J, et al: Aldehyde dehydrogenase 1-positive cancer
stem cells mediate metastasis and poor clinical outcome in
inflammatory breast cancer. Clin Cancer Res. 16:45–55. 2010.
View Article : Google Scholar
|
|
17
|
Ciccone V, Terzuoli E, Donnini S,
Giachetti A, Morbidelli L and Ziche M: Correction to: Stemness
marker ALDH1A1 promotes tumor angiogenesis via retinoic
acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells. J Exp
Clin Cancer Res. 37:3112018. View Article : Google Scholar
|
|
18
|
Terzuoli E, Bellan C, Aversa S, Ciccone V,
Morbidelli L, Giachetti A, Donnini S and Ziche M: ALDH3A1
overexpression in melanoma and lung tumors drives cancer stem cell
expansion, impairing immune surveillance through enhanced PD-L1
output. Cancers (Basel). 11:19632019. View Article : Google Scholar
|
|
19
|
Ramamoorthy P, Thomas SM, Kaushik G,
Subramaniam D, Chastain KM, Dhar A, Tawfik O, Kasi A, Sun W,
Ramalingam S, et al: Metastatic tumor-in-a-dish, a novel
multicellular organoid to study lung colonization and predict
therapeutic response. Cancer Res. 79:1681–1695. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Han SJ, Kwon S and Kim KS: Challenges of
applying multicellular tumor spheroids in preclinical phase. Cancer
Cell Int. 21:1522021. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cerebral Organoid Cryopreservation and
Immunofluorescence. https://www.stemcell.com/cerebral-organoid-cryosectioning-immunofluorescence.html.
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
23
|
Ciccone V, Zazzetta M and Morbidelli L:
Comparison of the effect of two hyaluronic acid preparations on
fibroblast and endothelial cell functions related to angiogenesis.
Cells. 8:14792019. View Article : Google Scholar
|
|
24
|
Ciccone V, Monti M, Monzani E, Casella L
and Morbidelli L: The metal-nonoate Ni(SalPipNONO) inhibits in
vitro tumor growth, invasiveness and angiogenesis. Oncotarget.
9:13353–13365. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Flori L, Macaluso M, Taglieri I, Sanmartin
C, Sgherri C, Leo MD, Ciccone V, Donnini S, Venturi F, Pistelli L,
et al: Development of fortified citrus olive oils: From their
production to their nutraceutical properties on the cardiovascular
system. Nutrients. 12:15572020. View Article : Google Scholar :
|
|
26
|
Ciccone V, Monti M, Antonini G, Mattoli L,
Burico M, Marini F, Maidecchi A and Morbidelli L: Efficacy of
AdipoDren® in reducing interleukin-1-induced lymphatic
endothelial hyperpermeability. J Vasc Res. 53:255–268. 2016.
View Article : Google Scholar
|
|
27
|
Samson JM, Menon DR, Smith DE, Baird E,
Kitano T, Gao D, Tan AC and Fujita M: Clinical implications of
ALDH1A1 and ALDH1A3 mRNA expression in melanoma subtypes. Chem Biol
Interact. 314:1088222019. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Gridley T: Notch signaling in vascular
development and physiology. Development. 134:2709–2718. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Rostama B, Peterson SM, Vary CPH and Liaw
L: Notch signal integration in the vasculature during remodeling.
Vascul Pharmacol. 63:97–104. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Welti J, Loges S, Dimmeler S and Carmeliet
P: Recent molecular discoveries in angiogenesis and antiangiogenic
therapies in cancer. J Clin Invest. 123:3190–3200. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Srivastava SK, Bhardwaj A, Arora S, Tyagi
N, Singh AP, Carter JE, Scammell JG, Fodstad Ø and Singh S:
Interleukin-8 is a key mediator of FKBP51-induced melanoma growth,
angiogenesis and metastasis. Br J Cancer. 112:1772–1781. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Li A, Dubey S, Varney ML, Dave BJ and
Singh RK: IL-8 directly enhanced endothelial cell survival,
proliferation, and matrix metalloproteinases production and
regulated angiogenesis. J Immunol. 170:3369–3376. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wu S, Singh S, Varney ML, Kindle S and
Singh RK: Modulation of CXCL-8 expression in human melanoma cells
regulates tumor growth, angiogenesis, invasion, and metastasis.
Cancer Med. 1:306–317. 2012. View Article : Google Scholar
|
|
34
|
Fernández-Chacón M, García-González I,
Mühleder S and Benedito R: Role of notch in endothelial biology.
Angiogenesis. 24:237–250. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Taslimi S and Das S: Angiogenesis and
angiogenesis inhibitors in brain tumors. Handbook of Brain Tumor
Chemotherapy, Molecular Therapeutics, and Immunotherapy. Newton HB:
2nd edition. Academic Press; Cambridge, MA: pp. 361–371. 2018
|
|
36
|
Groot AJ and Vooijs MA: The role of adams
in notch signaling. Adv Exp Med Biol. 727:15–36. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Fazio C and Ricciardiello L: Inflammation
and notch signaling: A crosstalk with opposite effects on
tumorigenesis. Cell Death Dis. 7:e25152016. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Christopoulos PF, Gjølberg TT, Krüger S,
Haraldsen G, Andersen JT and Sundlisæter E: Targeting the notch
signaling pathway in chronic inflammatory diseases. Front Immunol.
12:6682072021. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Tomita H, Tanaka K, Tanaka T and Hara A:
Aldehyde dehydrogenase 1A1 in stem cells and cancer. Oncotarget.
7:11018–11032. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Ribatti D: Cancer stem cells and tumor
angiogenesis. Cancer Lett. 321:13–17. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Fan YL, Zheng M, Tang YL and Liang XH: A
new perspective of vasculogenic mimicry: EMT and cancer stem cells
(Review). Oncol Lett. 6:1174–1180. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Dinavahi SS, Gowda R, Gowda K, Bazewicz
CG, Chirasani VR, Battu MB, Berg A, Dokholyan NV, Amin S and
Robertson GP: Development of a novel multi-isoform ALDH inhibitor
effective as an antimelanoma agent. Mol Cancer Ther. 19:447–459.
2020. View Article : Google Scholar
|
|
43
|
Yue L, Huang ZM, Fong S, Leong S, Jakowatz
JG, Charruyer-Reinwald A, Wei M and Ghadially R: Targeting ALDH1 to
decrease tumorigenicity, growth and metastasis of human melanoma.
Melanoma Res. 25:138–148. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Brassard-Jollive N, Monnot C, Muller L and
Germain S: In vitro 3D systems to model tumor angiogenesis and
interactions with stromal cells. Front Cell Dev Biol. 8:5949032020.
View Article : Google Scholar :
|
|
45
|
LaGory EL and Giaccia AJ: The
ever-expanding role of HIF in tumour and stromal biology. Nat Cell
Biol. 18:356–365. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Whiteside TL: The tumor microenvironment
and its role in promoting tumor growth. Oncogene. 27:5904–5912.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Ingangi V, Minopoli M, Ragone C, Motti ML
and Carriero MV: Role of microenvironment on the fate of
disseminating cancer stem cells. Front Oncol. 9:822019. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Jakobsson L, Franco CA, Bentley K, Collins
RT, Ponsioen B, Aspalter IM, Rosewell I, Busse M, Thurston G,
Medvinsky A, et al: Endothelial cells dynamically compete for the
tip cell position during angiogenic sprouting. Nat Cell Biol.
12:943–953. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Patel NS, Li JL, Generali D, Poulsom R,
Cranston DW and Harris AL: Up-regulation of delta-like 4 ligand in
human tumor vasculature and the role of basal expression in
endothelial cell function. Cancer Res. 65:8690–8697. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Peng HH, Liang S, Henderson AJ and Dong C:
Regulation of interleukin-8 expression in melanoma-stimulated
neutrophil inflammatory response. Exp Cell Res. 313:551–559. 2007.
View Article : Google Scholar
|
|
51
|
Rofstad EK and Halsør EF:
Hypoxia-associated spontaneous pulmonary metastasis in human
melanoma xenografts: Involvement of microvascular hot spots induced
in hypoxic foci by interleukin 8. Br J Cancer. 86:301–308. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Korbecki J, Kojder K, Kapczuk P, Kupnicka
P, Gawrońska-Szklarz B, Gutowska I, Chlubek D and
Baranowska-Bosiacka I: The effect of hypoxia on the expression of
CXC chemokines and CXC chemokine receptors-a review of literature.
Int J Mol Sci. 22:8432021. View Article : Google Scholar
|
|
53
|
Chang MM, Harper R, Hyde DM and Wu R: A
novel mechanism of retinoic acid-enhanced interleukin-8 gene
expression in airway epithelium. Am J Respir Cell Mol Biol.
22:502–510. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Mukherjee S, Date A, Patravale V, Korting
HC, Roeder A and Weindl G: Retinoids in the treatment of skin
aging: An overview of clinical efficacy and safety. Clin Interv
Aging. 1:327–348. 2006. View Article : Google Scholar
|
|
55
|
Duong V and Rochette-Egly C: The molecular
physiology of nuclear retinoic acid receptors. from health to
disease. Biochim Biophys Acta. 1812:1023–1031. 2011. View Article : Google Scholar
|
|
56
|
Dai X, Yamasaki K, Shirakata Y, Sayama K
and Hashimoto K: All-trans-retinoic acid induces interleukin-8 via
the nuclear factor-KappaB and P38 mitogen-activated protein kinase
pathways in normal human keratinocytes. J Invest Dermatol.
123:1078–1085. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Hoffmann E, Dittrich-Breiholz O, Holtmann
H and Kracht M: Multiple control of interleukin-8 gene expression.
J Leukoc Biol. 72:847–855. 2002.PubMed/NCBI
|
|
58
|
Kunsch C, Lang RK, Rosen CA and Shannon
MF: Synergistic transcriptional activation of the IL-8 gene by
NF-Kappa B P65 (RelA) and NF-IL-6. J Immunol. 153:153–164.
1994.PubMed/NCBI
|
|
59
|
Kunsch C and Rosen CA: NF-Kappa B
subunit-specific regulation of the interleukin-8 promoter. Mol Cell
Biol. 13:6137–6146. 1993.PubMed/NCBI
|
|
60
|
Harant H, de Martin R, Andrew PJ, Foglar
E, Dittrich C and Lindley IJ: Synergistic activation of
interleukin-8 gene transcription by all-trans-retinoic acid and
tumor necrosis factor-alpha involves the transcription factor
NF-KappaB. J Biol Chem. 271:26954–26961. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Jambrovics K, Uray IP, Keresztessy Z,
Keillor JW, Fésüs L and Balajthy Z: Transglutaminase 2 programs
differentiating acute promyelocytic leukemia cells in all-trans
retinoic acid treatment to inflammatory stage through NF-KB
activation. Haematologica. 104:505–515. 2019. View Article : Google Scholar :
|
|
62
|
Alfaro C, Sanmamed MF, Rodríguez-Ruiz ME,
Teijeira Á, Oñate C, González Á, Ponz M, Schalper KA, Pérez-Gracia
JL and Melero I: Interleukin-8 in cancer pathogenesis, treatment
and follow-up. Cancer Treat Rev. 60:24–31. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Yuan A, Chen JJW, Yao PL and Yang PC: The
role of interleukin-8 in cancer cells and microenvironment
interaction. Front Biosci. 10:853–865. 2005. View Article : Google Scholar
|
|
64
|
Singh S, Wu S, Varney M, Singh AP and
Singh RK: CXCR1 and CXCR2 silencing modulates CXCL8-dependent
endothelial cell proliferation, migration and capillary-like
structure formation. Microvasc Res. 82:318–325. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Waugh DJJ and Wilson C: The interleukin-8
pathway in cancer. Clin Cancer Res. 14:6735–6741. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Wang H, Tian Y, Wang J, Phillips KLE,
Binch ALA, Dunn S, Cross A, Chiverton N, Zheng Z, Shapiro IM, et
al: Inflammatory cytokines induce NOTCH signaling in nucleus
pulposus cells. J Biol Chem. 288:16761–16774. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Siekmann AF and Lawson ND: Notch
signalling and the regulation of angiogenesis. Cell Adh Migr.
1:104–106. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Benedito R, Roca C, Sörensen I, Adams S,
Gossler A, Fruttiger M and Adams RH: The notch ligands Dll4 and
jagged1 have opposing effects on angiogenesis. Cell. 137:1124–1135.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Akil A, Gutiérrez-García AK, Guenter R,
Rose JB, Beck AW, Chen H and Ren B: Notch signaling in vascular
endothelial cells, angiogenesis, and tumor progression: An update
and prospective. Front Cell Dev Biol. 9:6423522021. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Petreaca ML, Yao M, Liu Y, Defea K and
Martins-Green M: Transactivation of vascular endothelial growth
factor receptor-2 by interleukin-8 (IL-8/CXCL8) is required for
IL-8/CXCL8-induced endothelial permeability. Mol Biol Cell.
18:5014–5023. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Martin D, Galisteo R and Gutkind JS:
CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF)
expression and the autocrine activation of VEGFR2 in endothelial
cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1)
complex. J Biol Chem. 284:6038–6042. 2009. View Article : Google Scholar :
|
|
72
|
Yang L, Shi P, Zhao G, Xu J, Peng W, Zhang
J, Zhang G, Wang X, Dong Z, Chen F and Cui H: Targeting cancer stem
cell pathways for cancer therapy. Signal Transduct Target Ther.
5:82020. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Ciccone V, Morbidelli L, Ziche M and
Donnini S: How to conjugate the stemness marker ALDH1A1 with tumor
angiogenesis, progression, and drug resistance. Cancer Drug
Resistance. 3:26–37. 2020.PubMed/NCBI
|
