|
1
|
Hoste EAJ, Kellum JA, Selby NM, Zarbock A,
Palevsky PM, Bagshaw SM, Goldstein SL, Cerdá J and Chawla LS:
Global epidemiology and outcomes of acute kidney injury. Nat Rev
Nephrol. 14:607–625. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
James MT, Bhatt M, Pannu N and Tonelli M:
Long-term outcomes of acute kidney injury and strategies for
improved care. Nat Rev Nephrol. 16:193–205. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Turgut F, Awad AS and Abdel-Rahman EM:
Acute kidney injury: Medical causes and pathogenesis. J Clin Med.
12:3752023. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Zhao ZB, Marschner JA, Iwakura T, Li C,
Motrapu M, Kuang M, Popper B, Linkermann A, Klocke J, Enghard P, et
al: Tubular epithelial cell HMGB1 promotes AKI-CKD transition by
sensitizing cycling tubular cells to oxidative stress: A rationale
for targeting HMGB1 during AKI recovery. J Am Soc Nephrol.
34:394–411. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kurata Y and Nangaku M: Use of antibiotics
as a therapeutic approach to prevent AKI-to-CKD progression. Kidney
Int. 104:418–420. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Patidar KR, Naved MA, Grama A, Adibuzzaman
M, Aziz Ali A, Slaven JE, Desai AP, Ghabril MS, Nephew L, Chalasani
N and Orman ES: Acute kidney disease is common and associated with
poor outcomes in patients with cirrhosis and acute kidney injury. J
Hepatol. 77:108–115. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Shi L, Song Z, Li Y, Huang J, Zhao F, Luo
Y, Wang J, Deng F, Shadekejiang H, Zhang M, et al: MiR-20a-5p
alleviates kidney ischemia/reperfusion injury by targeting
ACSL4-dependent ferroptosis. Am J Transplant. 23:11–25. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Mansour SG, Bhatraju PK, Coca SG, Obeid W,
Wilson FP, Stanaway IB, Jia Y, Thiessen-Philbrook H, Go AS, Ikizler
TA, et al: Angiopoietins as prognostic markers for future kidney
disease and heart failure events after acute kidney injury. J Am
Soc Nephrol. 33:613–627. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Gewin LS: Renal fibrosis: Primacy of the
proximal tubule. Matrix Biol. 68-69:248–262. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Sheng L and Zhuang S: New insights into
the role and mechanism of partial epithelial-mesenchymal transition
in kidney fibrosis. Front Physiol. 11:5693222020. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Xu C, Hong Q, Zhuang K, Ren X, Cui S, Dong
Z, Wang Q, Bai X and Chen X: Regulation of pericyte metabolic
reprogramming restricts the AKI to CKD transition. Metabolism.
145:1555922023. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Lewis MP, Fine LG and Norman JT: Pexicrine
effects of basement membrane components on paracrine signaling by
renal tubular cells. Kidney Int. 49:48–58. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kuppe C, Ibrahim MM, Kranz J, Zhang X,
Ziegler S, Perales-Paton J, Jansen J, Reimer KC, Smith JR, Dobie R,
et al: Decoding myofibroblast origins in human kidney fibrosis.
Nature. 589:281–286. 2021. View Article : Google Scholar :
|
|
14
|
Gong H, Zheng C, Lyu X, Dong L, Tan S and
Zhang X: Inhibition of Sirt2 alleviates fibroblasts activation and
pulmonary fibrosis via Smad2/3 pathway. Front Pharmacol.
12:7561312021. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Khalil H, Kanisicak O, Prasad V, Correll
RN, Fu X, Schips T, Vagnozzi RJ, Liu R, Huynh T, Lee SJ, et al:
Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac
fibrosis. J Clin Invest. 127:3770–3783. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yang Q, Ren GL, Wei B, Jin J, Huang XR,
Shao W, Li J, Meng XM and Lan HY: Conditional knockout of
TGF-βRII/Smad2 signals protects against acute renal injury by
alleviating cell necroptosis, apoptosis and inflammation.
Theranostics. 9:8277–8293. 2019. View Article : Google Scholar :
|
|
17
|
Liu J, Kumar S, Dolzhenko E, Alvarado GF,
Guo J, Lu C, Chen Y, Li M, Dessing MC, Parvez RK, et al: Molecular
characterization of the transition from acute to chronic kidney
injury following ischemia/reperfusion. JCI Insight. 2:e947162017.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ni C, Chen Y, Xu Y, Zhao J, Li Q, Xiao C,
Wu Y, Wang J, Wang Y, Zhong Z, et al: Flavin containing
monooxygenase 2 prevents cardiac fibrosis via CYP2J3-SMURF2 axis.
Circ Res. July 5–2022.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Krueger SK, Williams DE, Yueh MF, Martin
SR, Hines RN, Raucy JL, Raucy JL, Dolphin CT, Shephard EA and
Phillips IR: Genetic polymorphisms of flavin-containing
monooxygenase (FMO). Drug Metab Rev. 34:523–532. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Siddens LK, Henderson MC, Vandyke JE,
Williams DE and Krueger SK: Characterization of mouse
flavin-containing monooxygenase transcript levels in lung and
liver, and activity of expressed isoforms. Biochem Pharmacol.
75:570–579. 2008. View Article : Google Scholar
|
|
21
|
Hsu DZ, Chu PY, Li YH, Chandrasekaran VR
and Liu MY: Role of flavin-containing-monooxygenase-dependent
neutrophil activation in thioacetamide-induced hepatic inflammation
in rats. Toxicology. 298:52–58. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Zhang J, Chaluvadi MR, Reddy R, Motika MS,
Richardson TA, Cashman JR and Morgan ET: Hepatic flavin-containing
monooxygenase gene regulation in different mouse inflammation
models. Drug Metab Dispos. 37:462–468. 2009. View Article : Google Scholar :
|
|
23
|
Ding H, Li J, Li Y, Yang M, Nie S, Zhou M,
Yang X, Liu Y and Hou FF: MicroRNA-10 negatively regulates
inflammation in diabetic kidney via targeting activation of the
NLRP3 inflammasome. Mol Ther. 29:2308–2320. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Shi L, Song Z, Li C, Deng F, Xia Y, Huang
J, Wu X and Zhu J: HDAC6 inhibition alleviates ischemia- and
Cisplatin-induced acute kidney injury by promoting autophagy.
Cells. 11:39512022. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Moore CL, Savenka AV and Basnakian AG:
TUNEL assay: A powerful tool for kidney injury evaluation. Int J
Mol Sci. 22:4122021. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
27
|
Lin X, Liang M and Feng XH: Smurf2 is a
ubiquitin E3 ligase mediating proteasome-dependent degradation of
Smad2 in transforming growth factor-beta signaling. J Biol Chem.
275:36818–36822. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Choi HS, Bhat A, Howington MB, Schaller
ML, Cox RL, Huang S, Beydoun S, Miller HA, Tuckowski AM, Mecano J,
et al: FMO rewires metabolism to promote longevity through
tryptophan and one carbon metabolism in C. elegans. Nat Commun.
14:5622023. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Krueger SK, Vandyke JE, Williams DE and
Hines RN: The role of flavin-containing monooxygenase (FMO) in the
metabolism of tamoxifen and other tertiary amines. Drug Metab Rev.
38:139–147. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bailleul G, Yang G, Nicoll CR, Mattevi A,
Fraaije MW and Mascotti ML: Evolution of enzyme functionality in
the flavin-containing monooxygenases. Nat Commun. 14:10422023.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Whetstine JR, Yueh MF, McCarver DG,
Williams DE, Park CS, Kang JH, Cha YN, Dolphin CT, Shephard EA,
Phillips IR and Hines RN: Ethnic differences in human
flavin-containing monooxygenase 2 (FMO2) polymorphisms: Detection
of expressed protein in African-Americans. Toxicol Appl Pharmacol.
168:216–224. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Hugonnard M, Benoit E, Longin-Sauvageon C
and Lattard V: Identification and characterization of the FMO2 gene
in Rattus norvegicus: A good model to study metabolic and
toxicological consequences of the FMO2 polymorphism.
Pharmacogenetics. 14:647–655. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Leiser SF, Miller H, Rossner R, Fletcher
M, Leonard A, Primitivo M, Rintala N, Ramos FJ, Miller DL and
Kaeberlein M: Cell nonautonomous activation of flavin-containing
monooxygenase promotes longevity and health span. Science.
350:1375–1378. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Liu BC, Tang TT, Lv LL and Lan HY: Renal
tubule injury: A driving force toward chronic kidney disease.
Kidney Int. 93:568–579. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Garimella PS, Katz R, Waikar SS,
Srivastava A, Schmidt I, Hoofnagle A, Palsson R, Rennke HG,
Stillman IE, Wang K, et al: Kidney tubulointerstitial fibrosis and
tubular secretion. Am J Kidney Dis. 79:709–716. 2022. View Article : Google Scholar :
|
|
36
|
Livingston MJ, Shu S, Fan Y, Li Z, Jiao Q,
Yin XM, Venkatachalam MA and Dong Z: Tubular cells produce FGF2 via
autophagy after acute kidney injury leading to fibroblast
activation and renal fibrosis. Autophagy. 19:256–277. 2023.
View Article : Google Scholar :
|
|
37
|
Li Z, Lu S and Li X: The role of metabolic
reprogramming in tubular epithelial cells during the progression of
acute kidney injury. Cell Mol Life Sci. 78:5731–5741. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Xu P, Chen C, Zhang Y, Dzieciatkowska M,
Brown BC, Zhang W, Xie T, Abdulmalik O, Song A, Tong C, et al:
Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney
disease by promoting oxygen delivery and carnitine homeostasis.
Cell Metab. 34:299–316.e6. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Zhang Z, Fan Y, Xie F, Zhou H, Jin K, Shao
L, Shi W, Fang P, Yang B, van Dam H, et al: Breast cancer
metastasis suppressor OTUD1 deubiquitinates SMAD7. Nat Commun.
8:21162017. View Article : Google Scholar : PubMed/NCBI
|
