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Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)

  • Authors:
    • Chenglin Kang
    • Haipeng He
    • Peng Liu
    • Yue Liu
    • Xiaomei Li
    • Jin Zhang
    • Hong Ran
    • Xianhai Zeng
    • Hailiang Zhao
    • Jiangqi Liu
    • Shuqi Qiu
  • View Affiliations / Copyright

    Affiliations: Department of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China, Department of Otolaryngology, Longgang ENT Hospital and Shenzhen Key Laboratory of ENT, Institute of ENT Shenzhen, Shenzhen, Guangdong 518172, P.R. China, Department of Otolaryngology, Second People's Hospital of Gansu Province, Lanzhou, Gansu 730000, P.R. China
    Copyright: © Kang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 117
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    Published online on: October 20, 2023
       https://doi.org/10.3892/ijmm.2023.5320
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Abstract

Allergic rhinitis (AR) is a common pathological condition in otorhinolaryngology. Its prevalence has been increasing worldwide and is becoming a major burden to the world population. Dendritic cells (DCs) are typically activated and matured after capturing, phagocytosing, and processing allergens during the immunopathogenesis of AR. In addition, the process of DC activation and maturation is accompanied by the production of exosomes, which are cell‑derived extracellular vesicles (EVs) that can carry proteins, lipids, nucleic acids, and other cargoes involved in intercellular communication and material transfer. In particular, DC‑derived exosomes (Dex) can participate in allergic immune responses, where the biological substances carried by them can have potentially important implications for both the pathogenesis and treatment of AR. Dex can also be exploited to carry anti‑allergy agents to effectively treat AR. This provides a novel method to explore the pathogenesis of and treatment strategies for AR further. Therefore, the present review focuses on the origin, composition, function, and biological characteristics of DCs, exosomes, and Dex, in addition to the possible relationship between Dex and AR.
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Copy and paste a formatted citation
Spandidos Publications style
Kang C, He H, Liu P, Liu Y, Li X, Zhang J, Ran H, Zeng X, Zhao H, Liu J, Liu J, et al: Role of dendritic cell‑derived exosomes in allergic rhinitis (Review). Int J Mol Med 52: 117, 2023.
APA
Kang, C., He, H., Liu, P., Liu, Y., Li, X., Zhang, J. ... Qiu, S. (2023). Role of dendritic cell‑derived exosomes in allergic rhinitis (Review). International Journal of Molecular Medicine, 52, 117. https://doi.org/10.3892/ijmm.2023.5320
MLA
Kang, C., He, H., Liu, P., Liu, Y., Li, X., Zhang, J., Ran, H., Zeng, X., Zhao, H., Liu, J., Qiu, S."Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)". International Journal of Molecular Medicine 52.6 (2023): 117.
Chicago
Kang, C., He, H., Liu, P., Liu, Y., Li, X., Zhang, J., Ran, H., Zeng, X., Zhao, H., Liu, J., Qiu, S."Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)". International Journal of Molecular Medicine 52, no. 6 (2023): 117. https://doi.org/10.3892/ijmm.2023.5320
Copy and paste a formatted citation
x
Spandidos Publications style
Kang C, He H, Liu P, Liu Y, Li X, Zhang J, Ran H, Zeng X, Zhao H, Liu J, Liu J, et al: Role of dendritic cell‑derived exosomes in allergic rhinitis (Review). Int J Mol Med 52: 117, 2023.
APA
Kang, C., He, H., Liu, P., Liu, Y., Li, X., Zhang, J. ... Qiu, S. (2023). Role of dendritic cell‑derived exosomes in allergic rhinitis (Review). International Journal of Molecular Medicine, 52, 117. https://doi.org/10.3892/ijmm.2023.5320
MLA
Kang, C., He, H., Liu, P., Liu, Y., Li, X., Zhang, J., Ran, H., Zeng, X., Zhao, H., Liu, J., Qiu, S."Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)". International Journal of Molecular Medicine 52.6 (2023): 117.
Chicago
Kang, C., He, H., Liu, P., Liu, Y., Li, X., Zhang, J., Ran, H., Zeng, X., Zhao, H., Liu, J., Qiu, S."Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)". International Journal of Molecular Medicine 52, no. 6 (2023): 117. https://doi.org/10.3892/ijmm.2023.5320
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