|
1
|
Vezzani B, Carinci M, Patergnani S,
Pasquin MP, Guarino A, Aziz N, Pinton P, Simonato M and Giorgi C:
The Dichotomous role of inflammation in the CNS: A mitochondrial
point of view. Biomolecules. 10:14372020. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Yilmaz C, Karali K, Fodelianaki G,
Gravanis A, Chavakis T, Charalampopoulos I and Alexaki VI:
Neurosteroids as regulators of neuroinflammation. Front
Neuroendocrinol. 55:1007882019. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Fontana L, Ghezzi L, Cross AH and Piccio
L: Effects of dietary restriction on neuroinflammation in
neurodegenerative diseases. J Exp Med. 218:e201900862021.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Biswas K: Microglia mediated
neuroinflammation in neurodegenerative diseases: A review on the
cell signaling pathways involved in microglial activation. J
Neuroimmunol. 383:5781802023. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Liu A, Yu L, Li X, Zhang K, Zhang W, So
KF, Tissir F, Qu Y and Zhou L: Celsr2-mediated morphological
polarization and functional phenotype of reactive astrocytes in
neural repair. Glia. 71:1985–2004. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Fan YY and Huo J: A1/A2 astrocytes in
central nervous system injuries and diseases: Angels or devils?
Neurochem Int. 148:1050802021. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Singh D: Astrocytic and microglial cells
as the modulators of neuroinflammation in Alzheimer's disease. J
Neuroinflammation. 19:2062022. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Gimenez MA, Sim J, Archambault AS, Klein
RS and Russell JH: A tumor necrosis factor receptor 1-dependent
conversation between central nervous system-specific T cells and
the central nervous system is required for inflammatory
infiltration of the spinal cord. Am J Pathol. 168:1200–1209. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Da Mesquita S, Fu Z and Kipnis J: The
meningeal lymphatic system: A new player in neurophysiology.
Neuron. 100:375–388. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Flores-Romero H, Dadsena S and Garcia-Saez
AJ: Mitochondrial pores at the crossroad between cell death and
inflammatory signaling. Mol Cell. 83:843–856. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wei Y, Miao Q, Zhang Q, Mao S, Li M, Xu X,
Xia X, Wei K, Fan Y, Zheng X, et al: Aerobic glycolysis is the
predominant means of glucose metabolism in neuronal somata, which
protects against oxidative damage. Nat Neurosci. 26:2081–2089.
2023. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Rose J, Brian C, Woods J, Pappa A,
Panayiotidis MI, Powers R and Franco R: Mitochondrial dysfunction
in glial cells: Implications for neuronal homeostasis and survival.
Toxicology. 391:109–115. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Rizzuto R, De Stefani D, Raffaello A and
Mammucari C: Mitochondria as sensors and regulators of calcium
signalling. Nat Rev Mol Cell Biol. 13:566–578. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Satarker S, Bojja SL, Gurram PC, Mudgal J,
Arora D and Nampoothiri M: Astrocytic glutamatergic transmission
and its implications in neurodegenerative disorders. Cells.
11:11392022. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Morales-Ropero JM, Arroyo-Urea S, Neubrand
VE, Martín-Oliva D, Marín-Teva JL, Cuadros MA, Vangheluwe P,
Navascués J, Mata AM and Sepúlveda MR: The endoplasmic reticulum
Ca(2+) -ATPase SERCA2b is upregulated in activated microglia and
its inhibition causes opposite effects on migration and
phagocytosis. Glia. 69:842–857. 2021. View Article : Google Scholar
|
|
16
|
Neel DV, Basu H, Gunner G, Bergstresser
MD, Giadone RM, Chung H, Miao R, Chou V, Brody E, Jiang X, et al:
Gasdermin-E mediates mitochondrial damage in axons and
neurodegeneration. Neuron. 111:1222–1240 e1229. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Borsche M, Pereira SL, Klein C and
Grünewald A: Mitochondria and Parkinson's disease: Clinical,
molecular, and translational aspects. J Parkinsons Dis. 11:45–60.
2021. View Article : Google Scholar :
|
|
18
|
Hinkle JT, Patel J, Panicker N,
Karuppagounder SS, Biswas D, Belingon B, Chen R, Brahmachari S,
Pletnikova O, Troncoso JC, et al: STING mediates neurodegeneration
and neuroinflammation in nigrostriatal α-synucleinopathy. Proc Natl
Acad Sci USA. 119:e21188191192022. View Article : Google Scholar
|
|
19
|
Pezone A, Olivieri F, Napoli MV, Procopio
A, Avvedimento EV and Gabrielli A: inflammation and DNA damage:
Cause, effect or both. Nat Rev Rheumatol. 19:200–211. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Duarte JN: Neuroinflammatory mechanisms of
mitochondrial dysfunction and neurodegeneration in glaucoma. J
Ophthalmol. 2021:45819092021.PubMed/NCBI
|
|
21
|
Yang Y, Liu Y, Zhu J, Song S, Huang Y,
Zhang W, Sun Y, Hao J, Yang X, Gao Q, et al:
Neuroinflammation-mediated mitochondrial dysregulation involved in
postoperative cognitive dysfunction. Free Radic Biol Med.
178:134–146. 2022. View Article : Google Scholar
|
|
22
|
Pan RY, Ma J, Kong XX, Wang XF, Li SS, Qi
XL, Yan YH, Cheng J, Liu Q, Jin W, et al: Sodium rutin ameliorates
Alzheimer's disease-like pathology by enhancing microglial
amyloid-β clearance. Sci Adv. 5:eaau63282019. View Article : Google Scholar
|
|
23
|
Joshi AU, Minhas PS, Liddelow SA,
Haileselassie B, Andreasson KI, Dorn GW II and Mochly-Rosen D:
Fragmented mitochondria released from microglia trigger A1
astrocytic response and propagate inflammatory neurodegeneration.
Nat Neurosci. 22:1635–1648. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Mi Y, Qi G, Vitali F, Shang Y, Raikes AC,
Wang T, Jin Y, Brinton RD, Gu H and Yin F: Loss of fatty acid
degradation by astrocytic mitochondria triggers neuroinflammation
and neurodegeneration. Nat Metab. 5:445–465. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Cenini G, Rub C, Bruderek M and Voos W:
Amyloid β-peptides interfere with mitochondrial preprotein import
competence by a coaggregation process. Mol Biol Cell. 27:3257–3272.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Bingol B, Tea JS, Phu L, Reichelt M,
Bakalarski CE, Song Q, Foreman O, Kirkpatrick DS and Sheng M: The
mitochondrial deubiquitinase USP30 opposes parkin-mediated
mitophagy. Nature. 510:370–375. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Annesley SJ and Fisher PR: Mitochondria in
health and disease. Cells. 8:6802019. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lin MT and Beal MF: Mitochondrial
dysfunction and oxidative stress in neurodegenerative diseases.
Nature. 443:787–795. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Johnson J, Mercado-Ayon E, Mercado-Ayon Y,
Dong YN, Halawani S, Ngaba L and Lynch DR: Mitochondrial
dysfunction in the development and progression of neurodegenerative
diseases. Arch Biochem Biophys. 702:1086982021. View Article : Google Scholar
|
|
30
|
Adebayo M, Singh S, Singh AP and Dasgupta
S: Mitochondrial fusion and fission: The fine-tune balance for
cellular homeostasis. FASEB J. 35:e216202021. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Alevriadou BR, Patel A, Noble M, Ghosh S,
Gohil VM, Stathopulos PB and Madesh M: Molecular nature and
physiological role of the mitochondrial calcium uniporter channel.
Am J Physiol Cell Physiol. 320:C465–C482. 2021. View Article : Google Scholar :
|
|
32
|
Fischer R and Maier O: Interrelation of
oxidative stress and inflammation in neurodegenerative disease:
Role of TNF. Oxid Med Cell Longev. 2015:6108132015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Teleanu DM, Niculescu AG, Lungu II, Radu
CI, Vladâcenco O, Roza E, Costăchescu B, Grumezescu AM and Teleanu
RI: An overview of oxidative stress, neuroinflammation, and
neurodegenerative diseases. Int J Mol Sci. 23:59382022. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Tsang T, Davis CI and Brady DC: Copper
biology. Curr Biol. 31:R421–R427. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Borisov VB, Siletsky SA, Nastasi MR and
Forte E: ROS defense systems and terminal oxidases in bacteria.
Antioxidants (Basel). 10:8392021. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Haider S, Batool Z, Ahmad S, Siddiqui RA
and Haleem DJ: Walnut supplementation reverses the
scopolamine-induced memory impairment by restoration of cholinergic
function via mitigating oxidative stress in rats: A potential
therapeutic intervention for age related neurodegenerative
disorders. Metab Brain Dis. 33:39–51. 2018. View Article : Google Scholar
|
|
37
|
Luque-Contreras D, Carvajal K, Toral-Rios
D, Franco-Bocanegra D and Campos-Pena V: Oxidative stress and
metabolic syndrome: Cause or consequence of Alzheimer's disease?
Oxid Med Cell Longev. 2014:4978022014. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Singh A, Kukreti R, Saso L and Kukreti S:
Oxidative stress: A key modulator in neurodegenerative diseases.
Molecules. 24:15832019. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Bhatia V and Sharma S: Role of
mitochondrial dysfunction, oxidative stress and autophagy in
progression of Alzheimer's disease. J Neurol Sci. 421:1172532021.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Zorov DB, Juhaszova M and Sollott SJ:
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS
release. Physiol Rev. 94:909–950. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Farkhondeh T, Mehrpour O, Forouzanfar F,
Roshanravan B and Samarghandian S: Oxidative stress and
mitochondrial dysfunction in organophosphate pesticide-induced
neurotoxicity and its amelioration: A review. Environ Sci Pollut
Res Int. 27:24799–24814. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Rowley S, Liang LP, Fulton R, Shimizu T,
Day B and Patel M: Mitochondrial respiration deficits driven by
reactive oxygen species in experimental temporal lobe epilepsy.
Neurobiol Dis. 75:151–158. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Bordoni L and Gabbianelli R: Mitochondrial
DNA and neurodegeneration: Any role for dietary antioxidants?
Antioxidants (Basel). 9:7642020. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Coppede F: Mitochondrial DNA methylation
and mitochondria-related epigenetics in neurodegeneration. Neural
Regen Res. 19:405–406. 2024. View Article : Google Scholar
|
|
45
|
Sharma VK, Singh TG and Mehta V: Stressed
mitochondria: A target to intrude alzheimer's disease.
Mitochondrion. 59:48–57. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Lin J and Epel E: Stress and telomere
shortening: Insights from cellular mechanisms. Ageing Res Rev.
73:1015072022. View Article : Google Scholar :
|
|
47
|
Ortiz JM and Swerdlow RH: Mitochondrial
dysfunction in Alzheimer's disease: Role in pathogenesis and novel
therapeutic opportunities. Br J Pharmacol. 176:3489–3507. 2019.
View Article : Google Scholar
|
|
48
|
Liu H, Zhang H, Zhang Y, Xu S, Zhao H, He
H and Liu X: Modeling mtDNA hypermethylation vicious circle
mediating Aβ-induced endothelial damage memory in HCMEC/D3 cell.
Aging (Albany NY). 12:18343–18362. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Rasheed M, Liang J, Wang C, Deng Y and
Chen Z: Epigenetic regulation of neuroinflammation in Parkinson's
disease. Int J Mol Sci. 22:49562021. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Youle RJ and van der Bliek AM:
Mitochondrial fission, fusion, and stress. Science. 337:1062–1065.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Song Y, Xu Y, Liu Y, Gao J, Feng L, Zhang
Y, Shi L and Zhang M, Guo D, Qi B and Zhang M: Mitochondrial
quality control in the maintenance of cardiovascular homeostasis:
The roles and interregulation of UPS, mitochondrial dynamics and
mitophagy. Oxid Med Cell Longev. 2021:39607732021. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Xie JH, Li YY and Jin J: The essential
functions of mitochondrial dynamics in immune cells. Cell Mol
Immunol. 17:712–721. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Chakrabarti S and Bisaglia M: Oxidative
stress and neuroinflammation in Parkinson's disease: The role of
dopamine oxidation products. Antioxidants (Basel). 12:9552023.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Picca A, Ferri E, Calvani R, Coelho-Junior
HJ, Marzetti E and Arosio B: Age-Associated glia remodeling and
mitochondrial dysfunction in neurodegeneration: Antioxidant
supplementation as a possible intervention. Nutrients. 14:24062022.
View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Dhapola R, Hota SS, Sarma P, Bhattacharyya
A, Medhi B and Reddy DH: Recent advances in molecular pathways and
therapeutic implications targeting neuroinflammation for
Alzheimer's disease. Inflammopharmacology. 29:1669–1681. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Chang YH, Lin HY, Shen FC, Su YJ, Chuang
JH, Lin TK, Liou CW, Lin CY, Weng SW and Wang PW: The causal role
of mitochondrial dynamics in regulating innate immunity in
diabetes. Front Endocrinol (Lausanne). 11:4452020. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Paik S, Kim JK, Silwal P, Sasakawa C and
Jo EK: An update on the regulatory mechanisms of NLRP3 inflammasome
activation. Cell Mol Immunol. 18:1141–1160. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Yurtsever I, Ustundag UV, Ünal I, Ateş PS
and Emekli-Alturfan E: Rifampicin decreases neuroinflammation to
maintain mitochondrial function and calcium homeostasis in
rotenone-treated zebrafish. Drug Chem Toxicol. 45:1544–1551. 2022.
View Article : Google Scholar
|
|
59
|
Kannurpatti SS: Mitochondrial calcium
homeostasis: Implications for neurovascular and neurometabolic
coupling. J Cereb Blood Flow Metab. 37:381–395. 2017. View Article : Google Scholar :
|
|
60
|
Poewe W, Seppi K, Tanner CM, Halliday GM,
Brundin P, Volkmann J, Schrag AE and Lang AE: Parkinson disease.
Nat Rev Dis Primers. 3:170132017. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Binvignat O and Olloquequi J:
Excitotoxicity as a target against neurodegenerative processes.
Curr Pharm Des. 26:1251–1262. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Yao L, Wu J, Koc S and Lu G: Genetic
imaging of neuroinflammation in Parkinson's disease: Recent
advancements. Front Cell Dev Biol. 9:6558192021. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Obrador E, Salvador R, Lopez-Blanch R,
Jihad-Jebbar A, Valles SL and Estrela JM: Oxidative stress,
neuroinflammation and mitochondria in the pathophysiology of
amyotrophic lateral sclerosis. Antioxidants (Basel). 9:9012020.
View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Cyrino LAR, Delwing-de Lima D, Ullmann OM
and Maia TP: Concepts of neuroinflammation and their relationship
with impaired mitochondrial functions in bipolar disorder. Front
Behav Neurosci. 15:6094872021. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Verkhratsky A, Rodriguez-Arellano JJ,
Parpura V and Zorec R: Astroglial calcium signalling in Alzheimer's
disease. Biochem Biophys Res Commun. 483:1005–1012. 2017.
View Article : Google Scholar
|
|
66
|
Casaril AM, Katsalifis A, Schmidt RM and
Bas-Orth C: Activated glia cells cause bioenergetic impairment of
neurons that can be rescued by knock-down of the mitochondrial
calcium uniporter. Biochem Biophys Res Commun. 608:45–51. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Garbincius JF and Elrod JW: Mitochondrial
calcium exchange in physiology and disease. Physiol Rev.
102:893–992. 2022. View Article : Google Scholar :
|
|
68
|
Baumgartner HK, Gerasimenko JV, Thorne C,
Ferdek P, Pozzan T, Tepikin AV, Petersen OH, Sutton R, Watson AJ
and Gerasimenko OV: Calcium elevation in mitochondria is the main
Ca2+ requirement for mitochondrial permeability transition pore
(mPTP) opening. J Biol Chem. 284:20796–20803. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Green DR and Kroemer G: The
pathophysiology of mitochondrial cell death. Science. 305:626–629.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Rimessi A, Previati M, Nigro F, Wieckowski
MR and Pinton P: Mitochondrial reactive oxygen species and
inflammation: Molecular mechanisms, diseases and promising
therapies. Int J Biochem Cell Biol. 81:281–293. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Marchi S, Patergnani S, Missiroli S,
Morciano G, Rimessi A, Wieckowski MR, Giorgi C and Pinton P:
Mitochondrial and endoplasmic reticulum calcium homeostasis and
cell death. Cell Calcium. 69:62–72. 2018. View Article : Google Scholar
|
|
72
|
Ooi K, Hu L, Feng Y, Han C, Ren X, Qian X,
Huang H, Chen S, Shi Q, Lin H, et al: Sigma-1 receptor activation
suppresses microglia M1 polarization via regulating endoplasmic
reticulum-mitochondria contact and mitochondrial functions in
stress-induced hypertension rats. Mol Neurobiol. 58:6625–6646.
2021. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Harland M, Torres S, Liu J and Wang X:
Neuronal mitochondria modulation of LPS-induced neuroinflammation.
J Neurosci. 40:1756–1765. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Lim D, Dematteis G, Tapella L, Genazzani
AA, Calì T, Brini M and Verkhratsky A: Ca(2+) handling at the
mitochondria-ER contact sites in neurodegeneration. Cell Calcium.
98:1024532021. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Krols M, van Isterdael G, Asselbergh B,
Kremer A, Lippens S, Timmerman V and Janssens S:
Mitochondria-associated membranes as hubs for neurodegeneration.
Acta Neuropathol. 131:505–523. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Sunanda T, Ray B, Mahalakshmi AM, Bhat A,
Rashan L, Rungratanawanich W, Song BJ, Essa MM, Sakharkar MK and
Chidambaram SB: Mitochondria-endoplasmic reticulum crosstalk in
Parkinson's disease: The role of brain renin angiotensin system
components. Biomolecules. 11:16692021. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Du H, Guo L, Fang F, Chen D, Sosunov AA,
McKhann GM, Yan Y, Wang C, Zhang H, Molkentin JD, et al:
Cyclophilin D deficiency attenuates mitochondrial and neuronal
perturbation and ameliorates learning and memory in Alzheimer's
disease. Nat Med. 14:1097–1105. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Ayabe T, Takahashi C, Ohya R and Ano Y:
β-Lactolin improves mitochondrial function in Abeta-treated mouse
hippocampal neuronal cell line and a human iPSC-derived neuronal
cell model of Alzheimer's disease. FASEB J. 36:e222772022.
View Article : Google Scholar
|
|
79
|
Reddy PH and Beal MF: Amyloid beta,
mitochondrial dysfunction and synaptic damage: Implications for
cognitive decline in aging and Alzheimer's disease. Trends Mol Med.
14:45–53. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Dursun E, Alaylioglu M, Bilgic B, Hanağası
H, Gürvit H, Emre M and Gezen-Ak D: Amyloid beta adsorption problem
with transfer plates in amyloid beta 1-42 IVD Kits. J Mol Neurosci.
67:534–539. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Han J, Park H, Maharana C, Gwon AR, Park
J, Baek SH, Bae HG, Cho Y, Kim HK, Sul JH, et al: Alzheimer's
disease-causing presenilin-1 mutations have deleterious effects on
mitochondrial function. Theranostics. 11:8855–8873. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Bai R, Guo J, Ye XY, Xie Y and Xie T:
Oxidative stress: The core pathogenesis and mechanism of
Alzheimer's disease. Ageing Res Rev. 77:1016192022. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Kowalczyk P, Sulejczak D, Kleczkowska P,
Bukowska-Ośko I, Kucia M, Popiel M, Wietrak E, Kramkowski K,
Wrzosek K and Kaczyńska K: Mitochondrial oxidative stress-A
causative factor and therapeutic target in many diseases. Int J Mol
Sci. 22:133842021. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Park MW, Cha HW, Kim J, Kim JH, Yang H,
Yoon S, Boonpraman N, Yi SS, Yoo ID and Moon JS: NOX4 promotes
ferroptosis of astrocytes by oxidative stress-induced lipid
peroxidation via the impairment of mitochondrial metabolism in
Alzheimer's diseases. Redox Biol. 41:1019472021. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Islam MT: Oxidative stress and
mitochondrial dysfunction-linked neurodegenerative disorders.
Neurol Res. 39:73–82. 2017. View Article : Google Scholar
|
|
86
|
Simpson DSA and Oliver PL: ROS generation
in microglia: Understanding oxidative stress and inflammation in
neurodegenerative disease. Antioxidants (Basel). 9:7432020.
View Article : Google Scholar : PubMed/NCBI
|
|
87
|
ElAli A, Bordeleau M, Theriault P, Filali
M, Lampron A and Rivest S: Tissue-plasminogen activator attenuates
Alzheimer's disease-related pathology development in APPswe/PS1
mice. Neuropsychopharmacology. 41:1297–1307. 2016. View Article : Google Scholar :
|
|
88
|
Li Y, Xia X, Wang Y and Zheng JC:
Mitochondrial dysfunction in microglia: A novel perspective for
pathogenesis of Alzheimer's disease. J Neuroinflammation.
19:2482022. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Massey N, Shrestha D, Bhat SM, Kondru N,
Charli A, Karriker LA, Kanthasamy AG and Charavaryamath C: Organic
dust-induced mitochondrial dysfunction could be targeted via
cGAS-STING or cytoplasmic NOX-2 inhibition using microglial cells
and brain slice culture models. Cell Tissue Res. 384:465–486. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Ising C, Venegas C, Zhang S, Scheiblich H,
Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM,
Tejera D, et al: NLRP3 inflammasome activation drives tau
pathology. Nature. 575:669–673. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Kelley N, Jeltema D, Duan Y and He Y: The
NLRP3 inflammasome: An overview of mechanisms of activation and
regulation. Int J Mol Sci. 20:33282019. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Jassim AH, Inman DM and Mitchell CH:
Crosstalk between dysfunctional mitochondria and inflammation in
glaucomatous neurodegeneration. Front Pharmacol. 12:6996232021.
View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Shaftel SS, Griffin WS and O'Banion MK:
The role of interleukin-1 in neuroinflammation and Alzheimer
disease: An evolving perspective. J Neuroinflammation. 5:72008.
View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Gonzalez-Reyes RE, Nava-Mesa MO,
Vargas-Sanchez K, Ariza-Salamanca D and Mora-Munoz L: Involvement
of astrocytes in Alzheimer's disease from a neuroinflammatory and
oxidative stress perspective. Front Mol Neurosci. 10:4272017.
View Article : Google Scholar
|
|
95
|
Sheng JG, Ito K, Skinner RD, Mrak RE,
Rovnaghi CR, Van Eldik LJ and Griffin WS: In vivo and in vitro
evidence supporting a role for the inflammatory cytokine
interleukin-1 as a driving force in Alzheimer pathogenesis.
Neurobiol Aging. 17:761–766. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
96
|
Bossu P, Ciaramella A, Moro ML,
Bellincampi L, Bernardini S, Federici G, Trequattrini A, Macciardi
F, Spoletini I, Di Iulio F, et al: Interleukin 18 gene
polymorphisms predict risk and outcome of Alzheimer's disease. J
Neurol Neurosurg Psychiatry. 78:807–811. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Gasser T: Molecular pathogenesis of
Parkinson disease: Insights from genetic studies. Expert Rev Mol
Med. 11:e222009. View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Braak H, Del Tredici K, Rub U, de Vos RA,
Jansen EN and Braak E: Staging of brain pathology related to
sporadic Parkinson's disease. Neurobiol Aging. 24:197–211. 2003.
View Article : Google Scholar
|
|
99
|
Han C, Liu Y, Dai R, Ismail N, Su W and Li
B: Ferroptosis and its potential role in human diseases. Front
Pharmacol. 11:2392020. View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Panicker N, Ge P, Dawson VL and Dawson TM:
The cell biology of Parkinson's disease. J Cell Biol.
220:e2020120952021. View Article : Google Scholar : PubMed/NCBI
|
|
101
|
Liu G, Zhang C, Yin J, Li X, Cheng F, Li
Y, Yang H, Uéda K, Chan P and Yu S: alpha-Synuclein is
differentially expressed in mitochondria from different rat brain
regions and dose-dependently down-regulates complex I activity.
Neurosci Lett. 454:187–192. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Thomas RR, Keeney PM and Bennett JP:
Impaired complex-I mitochondrial biogenesis in Parkinson disease
frontal cortex. J Parkinsons Dis. 2:67–76. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Bender A, Krishnan KJ, Morris CM, Taylor
GA, Reeve AK, Perry RH, Jaros E, Hersheson JS, Betts J, Klopstock
T, et al: High levels of mitochondrial DNA deletions in substantia
nigra neurons in aging and Parkinson disease. Nat Genet.
38:515–517. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
104
|
Valente EM, Bentivoglio AR, Dixon PH,
Ferraris A, Ialongo T, Frontali M, Albanese A and Wood NW:
Localization of a novel locus for autosomal recessive early-onset
parkinsonism, PARK6, on human chromosome 1p35-p36. Am J Hum Genet.
68:895–900. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
105
|
Fan Z, Pan YT, Zhang ZY, Yang H, Yu SY,
Zheng Y, Ma JH and Wang XM: Systemic activation of NLRP3
inflammasome and plasma α-synuclein levels are correlated with
motor severity and progression in Parkinson's disease. J
Neuroinflammation. 17:112020. View Article : Google Scholar
|
|
106
|
Sliter DA, Martinez J, Hao L, Chen X, Sun
N, Fischer TD, Burman JL, Li Y, Zhang Z and Narendra DP: Parkin and
PINK1 mitigate STING-induced inflammation. Nature. 561:258–262.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Hou X, Fiesel FC, Truban D, Casey MC, Lin
WL, Soto AI, Tacik P, Rousseau LG, Diehl NN, Heckman MG, et al:
Age- and disease-dependent increase of the mitophagy marker
phospho-ubiquitin in normal aging and Lewy body disease. Autophagy.
14:1404–1418. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
108
|
Di Maio R, Barrett PJ, Hoffman EK, Barrett
CW, Zharikov A, Borah A, Hu X, McCoy J, Chu CT, Burton EA, et al:
α-synuclein binds to TOM20 and inhibits mitochondrial protein
import in Parkinson's disease. Sci Transl Med. 8:342ra3782016.
View Article : Google Scholar
|
|
109
|
Vicario M, Cieri D, Vallese F, Catoni C,
Barazzuol L, Berto P, Grinzato A, Barbieri L, Brini M and Calì T: A
split-GFP tool reveals differences in the sub-mitochondrial
distribution of wt and mutant alpha-synuclein. Cell Death Dis.
10:8572019. View Article : Google Scholar : PubMed/NCBI
|
|
110
|
Devi L, Raghavendran V, Prabhu BM,
Avadhani NG and Anandatheerthavarada HK: Mitochondrial import and
accumulation of alpha-synuclein impair complex I in human
dopaminergic neuronal cultures and Parkinson disease brain. J Biol
Chem. 283:9089–9100. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
111
|
Mahul-Mellier AL, Burtscher J, Maharjan N,
Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW and Lashuel HA:
The process of Lewy body formation, rather than simply
alpha-synuclein fibrillization, is one of the major drivers of
neurodegeneration. Proc Natl Acad Sci USA. 117:4971–4982. 2020.
View Article : Google Scholar
|
|
112
|
Hsieh CH, Shaltouki A, Gonzalez AE, da
Cruz AB, Burbulla LF, St Lawrence E, Schüle B, Krainc D, Palmer TD
and Wang X: Functional impairment in miro degradation and mitophagy
is a shared feature in familial and sporadic Parkinson's disease.
Cell Stem Cell. 19:709–724. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
113
|
Godena VK, Brookes-Hocking N, Moller A,
Shaw G, Oswald M, Sancho RM, Miller CC, Whitworth AJ and De Vos KJ:
Increasing microtubule acetylation rescues axonal transport and
locomotor deficits caused by LRRK2 Roc-COR domain mutations. Nat
Commun. 5:52452014. View Article : Google Scholar : PubMed/NCBI
|
|
114
|
Bonello F, Hassoun SM, Mouton-Liger F,
Shin YS, Muscat A, Tesson C, Lesage S, Bear PM, Brice A, Krupp J,
et al: LRRK2 impairs PINK1/Parkin-dependent mitophagy via its
kinase activity: Pathologic insights into Parkinson's disease. Hum
Mol Genet. 28:1645–1660. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
115
|
Wang X, Chi J, Huang D, Ding L, Zhao X,
Jiang L, Yu Y and Gao F: α-synuclein promotes progression of
Parkinson's disease by upregulating autophagy signaling pathway to
activate NLRP3 inflammasome. Exp Ther Med. 19:931–938.
2020.PubMed/NCBI
|
|
116
|
Sarkar S, Malovic E, Harishchandra DS,
Ghaisas S, Panicker N, Charli A, Palanisamy BN, Rokad D, Jin H,
Anantharam V, et al: Mitochondrial impairment in microglia
amplifies NLRP3 inflammasome proinflammatory signaling in cell
culture and animal models of Parkinson's disease. NPJ Parkinsons
Dis. 3:302017. View Article : Google Scholar : PubMed/NCBI
|
|
117
|
Mouton-Liger F, Rosazza T, Sepulveda-Diaz
J, Ieang A, Hassoun SM, Claire E, Mangone G, Brice A, Michel PP,
Corvol JC and Corti O: Parkin deficiency modulates NLRP3
inflammasome activation by attenuating an A20-dependent negative
feedback loop. Glia. 66:1736–1751. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
118
|
Zhang C, Zhao M, Wang B, Su Z, Guo B, Qin
L, Zhang W and Zheng R: The Nrf2-NLRP3-caspase-1 axis mediates the
neuroprotective effects of celastrol in Parkinson's disease. Redox
Biol. 47:1021342021. View Article : Google Scholar : PubMed/NCBI
|
|
119
|
Faissner S, Plemel JR, Gold R and Yong VW:
Progressive multiple sclerosis: From pathophysiology to therapeutic
strategies. Nat Rev Drug Discov. 18:905–922. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
120
|
Barcelos IP, Troxell RM and Graves JS:
Mitochondrial dysfunction and multiple sclerosis. Biology (Basel).
8:372019.PubMed/NCBI
|
|
121
|
Steinman L: Multiple sclerosis: A
two-stage disease. Nat Immunol. 2:762–764. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
122
|
Lassmann H, van Horssen J and Mahad D:
Progressive multiple sclerosis: Pathology and pathogenesis. Nat Rev
Neurol. 8:647–656. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
123
|
Lopez-Domenech G and Kittler JT:
Mitochondrial regulation of local supply of energy in neurons. Curr
Opin Neurobiol. 81:1027472023. View Article : Google Scholar : PubMed/NCBI
|
|
124
|
Touil H, Li R, Zuroff L, Moore CS, Healy
L, Cignarella F, Piccio L, Ludwin S, Prat A, Gommerman J, et al:
Cross-talk between B cells, microglia and macrophages, and
implications to central nervous system compartmentalized
inflammation and progressive multiple sclerosis. EBioMedicine.
96:1047892023. View Article : Google Scholar : PubMed/NCBI
|
|
125
|
Campbell GR, Ziabreva I, Reeve AK,
Krishnan KJ, Reynolds R, Howell O, Lassmann H, Turnbull DM and
Mahad DJ: Mitochondrial DNA deletions and neurodegeneration in
multiple sclerosis. Ann Neurol. 69:481–492. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
126
|
Witte ME, Nijland PG, Drexhage JA,
Gerritsen W, Geerts D, van Het Hof B, Reijerkerk A, de Vries HE,
van der Valk P and van Horssen J: Reduced expression of PGC-1alpha
partly underlies mitochondrial changes and correlates with neuronal
loss in multiple sclerosis cortex. Acta Neuropathol. 125:231–243.
2013. View Article : Google Scholar
|
|
127
|
Haider L, Fischer MT, Frischer JM, Bauer
J, Höftberger R, Botond G, Esterbauer H, Binder CJ, Witztum JL and
Lassmann H: Oxidative damage in multiple sclerosis lesions. Brain.
134:1914–1924. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
128
|
Dziedzic T, Metz I, Dallenga T, König FB,
Müller S, Stadelmann C and Brück W: Wallerian degeneration: A major
component of early axonal pathology in multiple sclerosis. Brain
Pathol. 20:976–985. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
129
|
Madsen PM, Pinto M, Patel S, McCarthy S,
Gao H, Taherian M, Karmally S, Pereira CV, Dvoriantchikova G,
Ivanov D, et al: Mitochondrial DNA double-strand breaks in
oligodendrocytes cause demyelination, axonal injury, and CNS
inflammation. J Neurosci. 37:10185–10199. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
130
|
Singhal NK, Alkhayer K, Shelestak J,
Clements R, Freeman E and McDonough J: Erythropoietin upregulates
brain hemoglobin expression and supports neuronal mitochondrial
activity. Mol Neurobiol. 55:8051–8058. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
131
|
Aboul-Enein F, Krssak M, Hoftberger R,
Prayer D and Kristoferitsch W: Reduced NAA-levels in the NAWM of
patients with MS is a feature of progression. A study with
quantitative magnetic resonance spectroscopy at 3 tesla. PLoS One.
5:e116252010. View Article : Google Scholar : PubMed/NCBI
|
|
132
|
Dominicis A, Del Giovane A, Torreggiani M,
Recchia AD, Ciccarone F, Ciriolo MR and Ragnini-Wilson A:
N-Acetylaspartate drives oligodendroglial differentiation via
histone deacetylase activation. Cells. 12:18612023. View Article : Google Scholar : PubMed/NCBI
|
|
133
|
Kadowaki A and Quintana FJ: The NLRP3
inflammasome in progressive multiple sclerosis. Brain.
143:1286–1288. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
134
|
Ferecsko AS, Smallwood MJ, Moore A, Liddle
C, Newcombe J, Holley J, Whatmore J, Gutowski NJ and Eggleton P:
STING-triggered CNS inflammation in human neurodegenerative
diseases. Biomedicines. 11:13752023. View Article : Google Scholar : PubMed/NCBI
|
|
135
|
Thijs RD, Surges R, O'Brien TJ and Sander
JW: Epilepsy in adults. Lancet. 393:689–701. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
136
|
Fabisiak T and Patel M: Crosstalk between
neuroinflammation and oxidative stress in epilepsy. Front Cell Dev
Biol. 10:9769532022. View Article : Google Scholar : PubMed/NCBI
|
|
137
|
Loscher W and Klein P: The pharmacology
and clinical efficacy of antiseizure medications: From bromide
salts to cenobamate and beyond. CNS Drugs. 35:935–963. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
138
|
Pearson-Smith JN and Patel M: Metabolic
dysfunction and oxidative stress in epilepsy. Int J Mol Sci.
18:23652017. View Article : Google Scholar : PubMed/NCBI
|
|
139
|
Geronzi U, Lotti F and Grosso S: Oxidative
stress in epilepsy. Expert Rev Neurother. 18:427–434. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
140
|
Terrone G, Balosso S, Pauletti A, Ravizza
T and Vezzani A: Inflammation and reactive oxygen species as
disease modifiers in epilepsy. Neuropharmacology. 167:1077422020.
View Article : Google Scholar
|
|
141
|
Ahras-Sifi N and Laraba-Djebari F:
Immunomodulatory and protective effects of interleukin-4 on the
neuropathological alterations induced by a potassium channel
blocker. J Neuroimmunol. 355:5775492021. View Article : Google Scholar : PubMed/NCBI
|
|
142
|
Rahman S: Pathophysiology of mitochondrial
disease causing epilepsy and status epilepticus. Epilepsy Behav.
49:71–75. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
143
|
Liang LP, Waldbaum S, Rowley S, Huang TT,
Day BJ and Patel M: Mitochondrial oxidative stress and epilepsy in
SOD2 deficient mice: Attenuation by a lipophilic metalloporphyrin.
Neurobiol Dis. 45:1068–1076. 2012. View Article : Google Scholar :
|
|
144
|
Fulton RE, Pearson-Smith JN, Huynh CQ,
Fabisiak T, Liang LP, Aivazidis S, High BA, Buscaglia G, Corrigan
T, Valdez R, et al: Neuron-specific mitochondrial oxidative stress
results in epilepsy, glucose dysregulation and a striking astrocyte
response. Neurobiol Dis. 158:1054702021. View Article : Google Scholar : PubMed/NCBI
|
|
145
|
Zhang S, Chen F, Zhai F and Liang S: Role
of HMGB1/TLR4 and IL-1β/IL-1R1 signaling pathways in epilepsy.
Front Neurol. 13:9042252022. View Article : Google Scholar
|
|
146
|
Kim JE and Kang TC: Differential roles of
mitochondrial translocation of active caspase-3 and HMGB1 in
neuronal death induced by status epilepticus. Front Cell Neurosci.
12:3012018. View Article : Google Scholar : PubMed/NCBI
|
|
147
|
Hyun HW, Ko AR and Kang TC: Mitochondrial
translocation of high mobility group box 1 facilitates LIM kinase
2-mediated programmed necrotic neuronal death. Front Cell Neurosci.
10:992016. View Article : Google Scholar : PubMed/NCBI
|
|
148
|
Kim JE, Park H, Kim TH and Kang TC: LONP1
regulates mitochondrial accumulations of HMGB1 and Caspase-3 in CA1
and PV neurons following status epilepticus. Int J Mol Sci.
22:22752021. View Article : Google Scholar : PubMed/NCBI
|
|
149
|
Pauletti A, Terrone G, Shekh-Ahmad T,
Salamone A, Ravizza T, Rizzi M, Pastore A, Pascente R, Liang LP,
Villa BR, et al: Targeting oxidative stress improves disease
outcomes in a rat model of acquired epilepsy. Brain. 142:e392019.
View Article : Google Scholar : PubMed/NCBI
|
|
150
|
Kumar P, Osahon OW and Sekhar RV: GlyNAC
(Glycine and N-Acetylcysteine) supplementation in mice increases
length of life by correcting glutathione deficiency, oxidative
stress, mitochondrial dysfunction, abnormalities in mitophagy and
nutrient sensing, and genomic damage. Nutrients. 14:11142022.
View Article : Google Scholar : PubMed/NCBI
|
|
151
|
Mohseni-Moghaddam P, Roghani M,
Khaleghzadeh-Ahangar H, Sadr SS and Sala C: A literature overview
on epilepsy and inflammasome activation. Brain Res Bull.
172:229–235. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
152
|
Abais JM, Zhang C, Xia M, Liu Q, Gehr TW,
Boini KM and Li PL: NADPH oxidase-mediated triggering of
inflammasome activation in mouse podocytes and glomeruli during
hyperhomocysteinemia. Antioxid Redox Signal. 18:1537–1548. 2013.
View Article : Google Scholar :
|
|
153
|
Subramanian N, Natarajan K, Clatworthy MR,
Wang Z and Germain RN: The adaptor MAVS promotes NLRP3
mitochondrial localization and inflammasome activation. Cell.
153:348–361. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
154
|
Zhou R, Yazdi AS, Menu P and Tschopp J: A
role for mitochondria in NLRP3 inflammasome activation. Nature.
469:221–225. 2011. View Article : Google Scholar
|
|
155
|
Rong S, Wan D, Fan Y, Liu S, Sun K, Huo J,
Zhang P, Li X, Xie X, Wang F and Sun T: Amentoflavone affects
epileptogenesis and exerts neuroprotective effects by inhibiting
NLRP3 inflammasome. Front Pharmacol. 10:8562019. View Article : Google Scholar : PubMed/NCBI
|
|
156
|
Liu Z, Xian H, Ye X, Chen J, Ma Y and
Huang W: Increased levels of NLRP3 in children with febrile
seizures. Brain Dev. 42:336–341. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
157
|
de Brito Toscano EC, Vieira EL, Dias BB,
Caliari MV, Gonçalves AP, Giannetti AV, Siqueira JM, Suemoto CK,
Leite RE, Nitrini R, et al: NLRP3 and NLRP1 inflammasomes are
up-regulated in patients with mesial temporal lobe epilepsy and may
contribute to overexpression of caspase-1 and IL-β in sclerotic
hippocampi. Brain Res. 1752:1472302021. View Article : Google Scholar
|
|
158
|
Tan CC, Zhang JG, Tan MS, Chen H, Meng DW,
Jiang T, Meng XF, Li Y, Sun Z, Li MM, et al: NLRP1 inflammasome is
activated in patients with medial temporal lobe epilepsy and
contributes to neuronal pyroptosis in amygdala kindling-induced rat
model. J Neuroinflammation. 12:182015. View Article : Google Scholar : PubMed/NCBI
|
|
159
|
Samidurai M, Tarale P, Janarthanam C,
Estrada CG, Gordon R, Zenitsky G, Jin H, Anantharam V, Kanthasamy
AG and Kanthasamy A: tumor necrosis factor-like weak inducer of
apoptosis (TWEAK) enhances activation of STAT3/NLRC4 inflammasome
signaling axis through PKCdelta in AStrocytes: Implications for
Parkinson's disease. Cells. 9:18312020. View Article : Google Scholar
|
|
160
|
Zadori D, Klivenyi P, Szalardy L, Fulop F,
Toldi J and Vecsei L: Mitochondrial disturbances, excitotoxicity,
neuroinflammation and kynurenines: Novel therapeutic strategies for
neurodegenerative disorders. J Neurol Sci. 322:187–191. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
161
|
Prasuhn J, Davis RL and Kumar KR:
Targeting mitochondrial impairment in Parkinson's disease:
Challenges and opportunities. Front Cell Dev Biol. 8:6154612020.
View Article : Google Scholar
|
|
162
|
Vos M, Esposito G, Edirisinghe JN, Vilain
S, Haddad DM, Slabbaert JR, Van Meensel S, Schaap O, De Strooper B,
Meganathan R, et al: Vitamin K2 is a mitochondrial electron carrier
that rescues pink1 deficiency. Science. 336:1306–1310. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
163
|
Bronzuoli MR, Iacomino A, Steardo L and
Scuderi C: Targeting neuroinflammation in Alzheimer's disease. J
Inflamm Res. 9:199–208. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
164
|
Fu AK, Hung KW, Yuen MY, Zhou X, Mak DS,
Chan IC, Cheung TH, Zhang B, Fu WY, Liew FY and Ip NY: IL-33
ameliorates Alzheimer's disease-like pathology and cognitive
decline. Proc Natl Acad Sci USA. 113:E2705–E2713. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
165
|
Wang X, Sun G, Feng T, Zhang J, Huang X,
Wang T, Xie Z, Chu X, Yang J, Wang H, et al: Sodium oligomannate
therapeutically remodels gut microbiota and suppresses gut
bacterial amino acids-shaped neuroinflammation to inhibit
Alzheimer's disease progression. Cell Res. 29:787–803. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
166
|
Regen F, Hellmann-Regen J, Costantini E
and Reale M: Neuroinflammation and Alzheimer's disease:
Implications for microglial activation. Curr Alzheimer Res.
14:1140–1148. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
167
|
La Torre ME, Cianciulli A, Monda V, Monda
M, Filannino FM, Antonucci L, Valenzano A, Cibelli G, Porro C,
Messina G, et al: α-Tocopherol protects
lipopolysaccharide-activated BV2 microglia. Molecules. 28:33402023.
View Article : Google Scholar
|
|
168
|
Shabab T, Khanabdali R, Moghadamtousi SZ,
Kadir HA and Mohan G: Neuroinflammation pathways: A general review.
Int J Neurosci. 127:624–633. 2017. View Article : Google Scholar
|
|
169
|
Heger LM, Wise RM, Hees JT, Harbauer AB
and Burbulla LF: Mitochondrial phenotypes in Parkinson's diseases-a
focus on human iPSC-derived dopaminergic neurons. Cells.
10:34362021. View Article : Google Scholar : PubMed/NCBI
|
|
170
|
Yu G, Wang Y and Zhao J: Inhibitory effect
of mitoquinone against the α-synuclein fibrillation and relevant
neurotoxicity: Possible role in inhibition of Parkinson's disease.
Biol Chem. 403:253–263. 2022. View Article : Google Scholar
|
|
171
|
Snow BJ, Rolfe FL, Lockhart MM, Frampton
CM, O'Sullivan JD, Fung V, Smith RA, Murphy MP and Taylor KM;
Protect Study Group: A double-blind, placebo-controlled study to
assess the mitochondria-targeted antioxidant MitoQ as a
disease-modifying therapy in Parkinson's disease. Mov Disord.
25:1670–1674. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
172
|
Lehmann S, Loh SH and Martins LM:
Enhancing NAD(+) salvage metabolism is neuroprotective in a PINK1
model of Parkinson's disease. Biol Open. 6:141–147. 2017.
|
|
173
|
Monti DA, Zabrecky G, Kremens D, Liang TW,
Wintering NA, Bazzan AJ, Zhong L, Bowens BK, Chervoneva I, Intenzo
C and Newberg AB: N-Acetyl cysteine is associated with dopaminergic
improvement in Parkinson's disease. Clin Pharmacol Ther.
106:884–890. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
174
|
Sathe AG, Tuite P, Chen C, Ma Y, Chen W,
Cloyd J, Low WC, Steer CJ, Lee BY, Zhu XH and Coles LD:
Pharmacokinetics, safety, and tolerability of orally administered
ursodeoxycholic acid in patients with Parkinson's disease-a pilot
study. J Clin Pharmacol. 60:744–750. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
175
|
Bell SM, Barnes K, Clemmens H, Al-Rafiah
AR, Al-Ofi EA, Leech V, Bandmann O, Shaw PJ, Blackburn DJ,
Ferraiuolo L and Mortiboys H: Ursodeoxycholic acid improves
mitochondrial function and redistributes Drp1 in fibroblasts from
patients with either sporadic or familial Alzheimer's Disease. J
Mol Biol. 430:3942–3953. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
176
|
Lin MW, Lin CC, Chen YH, Yang HB and Hung
SY: Celastrol inhibits dopaminergic neuronal death of Parkinson's
disease through activating mitophagy. Antioxidants (Basel).
9:372019. View Article : Google Scholar
|
|
177
|
Bido S, Soria FN, Fan RZ, Bezard E and
Tieu K: Mitochondrial division inhibitor-1 is neuroprotective in
the A53T-α-synuclein rat model of Parkinson's disease. Sci Rep.
7:74952017. View Article : Google Scholar
|
|
178
|
Curtis WM, Seeds WA, Mattson MP and
Bradshaw PC: NADPH and mitochondrial quality control as targets for
a circadian-based fasting and exercise therapy for the treatment of
Parkinson's disease. Cells. 11:24162022. View Article : Google Scholar : PubMed/NCBI
|
|
179
|
Ferreira AFF, Binda KH, Singulani MP,
Pereira CPM, Ferrari GD, Alberici LC, Real CC and Britto LR:
Physical exercise protects against mitochondria alterations in the
6-hidroxydopamine rat model of Parkinson's disease. Behav Brain
Res. 387:1126072020. View Article : Google Scholar : PubMed/NCBI
|
|
180
|
Kappos L, Bar-Or A, Cree BAC, Fox RJ,
Giovannoni G, Gold R, Vermersch P, Arnold DL, Arnould S, Scherz T,
et al: Siponimod versus placebo in secondary progressive multiple
sclerosis (EXPAND): A double-blind, randomised, phase 3 study.
Lancet. 391:1263–1273. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
181
|
Montalban X, Hauser SL, Kappos L, Arnold
DL, Bar-Or A, Comi G, de Seze J, Giovannoni G, Hartung HP, Hemmer
B, et al: Ocrelizumab versus placebo in primary progressive
multiple sclerosis. N Engl J Med. 376:209–220. 2017. View Article : Google Scholar
|
|
182
|
Lublin F, Miller DH, Freedman MS, Cree
BAC, Wolinsky JS, Weiner H, Lubetzki C, Hartung HP, Montalban X,
Uitdehaag BMJ, et al: Oral fingolimod in primary progressive
multiple sclerosis (INFORMS): A phase 3, randomised, double-blind,
placebo-controlled trial. Lancet. 387:1075–1084. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
183
|
Waxman SG: Axonal conduction and injury in
multiple sclerosis: The role of sodium channels. Nat Rev Neurosci.
7:932–941. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
184
|
Picone P and Nuzzo D: Promising treatment
for multiple sclerosis: Mitochondrial transplantation. Int J Mol
Sci. 23:22452022. View Article : Google Scholar : PubMed/NCBI
|
|
185
|
Moos WH, Faller DV, Glavas IP, Kanara I,
Kodukula K, Pernokas J, Pernokas M, Pinkert CA, Powers WR, Sampani
K, et al: Epilepsy: Mitochondrial connections to the 'Sacred'
disease. Mitochondrion. 72:84–101. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
186
|
Silvestro S, Mammana S, Cavalli E,
Bramanti P and Mazzon E: Use of cannabidiol in the treatment of
epilepsy: Efficacy and security in clinical trials. Molecules.
24:14592019. View Article : Google Scholar : PubMed/NCBI
|
|
187
|
Ramirez A, Old W, Selwood DL and Liu X:
Cannabidiol activates PINK1-Parkin-dependent mitophagy and
mitochondrial-derived vesicles. Eur J Cell Biol. 101:1511852022.
View Article : Google Scholar :
|
|
188
|
Bhunia S, Kolishetti N, Arias AY, Vashist
A and Nair M: Cannabidiol for neurodegenerative disorders: A
comprehensive review. Front Pharmacol. 13:9897172022. View Article : Google Scholar : PubMed/NCBI
|
|
189
|
Britch SC, Babalonis S and Walsh SL:
Cannabidiol: Pharmacology and therapeutic targets.
Psychopharmacology (Berl). 238:9–28. 2021. View Article : Google Scholar
|
|
190
|
Aledo-Serrano A, Hariramani R,
Gonzalez-Martinez A, Álvarez-Troncoso J, Toledano R, Bayat A,
Garcia-Morales I, Becerra JL, Villegas-Martínez I,
Beltran-Corbellini A and Gil-Nagel A: Anakinra and tocilizumab in
the chronic phase of febrile infection-related epilepsy syndrome
(FIRES): Effectiveness and safety from a case-series. Seizure.
100:51–55. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
191
|
Stienen MN, Haghikia A, Dambach H, Thöne
J, Wiemann M, Gold R, Chan A, Dermietzel R, Faustmann PM, Hinkerohe
D and Prochnow N: Anti-inflammatory effects of the anticonvulsant
drug levetiracetam on electrophysiological properties of astroglia
are mediated via TGFβ1 regulation. Br J Pharmacol. 162:491–507.
2011. View Article : Google Scholar :
|
|
192
|
Stockburger C, Miano D, Baeumlisberger M,
Pallas T, Arrey TN, Karas M, Friedland K and Müller WE: A
mitochondrial role of sv2a protein in aging and Alzheimer's
disease: Studies with levetiracetam. J Alzheimers Dis. 50:201–215.
2016. View Article : Google Scholar
|
|
193
|
Yang N, Guan QW, Chen FH, Xia QX, Yin XX,
Zhou HH and Mao XY: Antioxidants targeting mitochondrial oxidative
stress: Promising neuroprotectants for epilepsy. Oxid Med Cell
Longev. 2020:66871852020. View Article : Google Scholar : PubMed/NCBI
|
|
194
|
Fields M, Marcuzzi A, Gonelli A, Celeghini
C, Maximova N and Rimondi E: Mitochondria-Targeted antioxidants, an
innovative class of antioxidant compounds for neurodegenerative
diseases: Perspectives and limitations. Int J Mol Sci. 24:37392023.
View Article : Google Scholar : PubMed/NCBI
|
|
195
|
Huenchuguala S and Segura-Aguilar J:
Single-neuron neurodegeneration as a degenerative model for
Parkinson's disease. Neural Regen Res. 19:529–535. 2024. View Article : Google Scholar
|
|
196
|
Leitao-Rocha A, Guedes-Dias P, Pinho BR
and Oliveira JM: Trends in mitochondrial therapeutics for
neurological disease. Curr Med Chem. 22:2458–2467. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
197
|
Yoshinaga N and Numata K: Rational designs
at the forefront of mitochondria-targeted gene delivery: Recent
progress and future perspectives. ACS Biomater Sci Eng. 8:348–359.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
198
|
Silva-Pinheiro P and Minczuk M: The
potential of mitochondrial genome engineering. Nat Rev Genet.
23:199–214. 2022. View Article : Google Scholar
|
