Int J Mol Med 43: [Related article:] 185-198, 2019; DOI:
10.3892/ijmm.2018.3960
Following the publication of the above article, an
interested reader drew to the Editor's attention that various of
the histological structural images shown in Fig. 5 on p. 190 were strikingly similar
to data that were featured in Fig. 1A of a previous paper by the
same research group that appeared in the Journal Laboratory
Animal Research. On re-examining their original data, the
authors confirmed that an error occurred during the paper
submission/production process, and that Fig. 5 did not appear in the above
article as the authors had intended.
 | Figure 5Histological structure of transverse
colon collected from Lop-induced constipated rats. Following the
collection of transverse colons from the Non-, EtRLP-,
Lop+Vehicle-, Lop+EtRLP- and Lop+BisaC-treated groups, H&E
stained sections of these tissues were observed at two
magnifications via light microscopy (left and middle column). Mucin
on the tissue sections was stained with alcian blue (right column).
Crypt layer thickness, muscle thickness, and villus length in
transverse colon were measured in H&E stained images with the
Leica Application Suite software. EtRLP, Red Liriope platyphylla
extract; Lop, loperamide; BisaC, bisacodyl; H&E, hematoxylin
and eosin. |
The correct version of Fig. 5, containing the data that the
authors intended for inclusion in this article, is shown on the
next page. Also shown is a corrected version of Table II corresponding to the
replacement version of Fig. 5,
containing data that are derived from an analysis of the data shown
in this figure. Furthermore, the replacement of the images in
Fig. 5, and the revisions of the
data made in Table II, also
dictate that the following changes are needed to be made in the
main text of the paper (all associated with Results section on p.
191, 'Recovery effect of EtRLP on histological alterations of
the transverse colon' subsection): The sentences in lines 9-14
of this section should now read as following (changes from the
original text are highlighted in bold): 'Following Lop+EtRLP
or Lop+Bisac treatments, the villus length increased by
270-290% relative to the Lop+Vehicle-treated group (Fig. 5 and Table II). Furthermore, the alterations
in muscle thickness were similar to those in villus length,
although crypt layer thickness only increased by 145-150%
relative to the Lop+Vehicle-treated group (Fig. 5 and Table II)'.
 | Table IIHistological parameters of
experimental rats with Lop-induced constipation. |
Table II
Histological parameters of
experimental rats with Lop-induced constipation.
| Categories | Non-treated E | tRLP | Loperamide
|
|---|
| Vehicle | EtRLP | BisaC |
|---|
| Villus length
(μm) | 287.9±14.0 | 228.7±20.1 | 79.5±14.1a | 225.5±14.6b | 217.0±15.0b |
| Muscle thickness
(μm) | 70.6±4.0 | 63.0±4.3 | 22.4±1.5a | 55.2±3.6b | 55.4±4.9b |
| Crypt layer thickness
(μm) | 111.1±37.0 | 101.5±26.1 | 51.2±2.2a | 76.6±14.7b | 75.3±16.2b |
| Number of goblet cell
(ea) | 315.4±16.3 | 316.4±18.7 | 161.3±8.1a | 256.0±17.7b | 256.8±20.6b |
| Number of crypt of
lieberkuhn (ea) | 30.2±3.3 | 25.8±3.3 | 11.8±3.5a | 19.8±2.9b | 19.6±3.8b |
Note that the errors made during the assembly of
Fig. 5 and Table II did not grossly affect the
overall conclusions reported in the paper. All the authors agree
with the publication of this corrigendum, and are grateful to the
Editor of International Journal of Molecular Medicine for
allowing them the opportunity to publish this. They also apologize
to the readership for any inconvenience caused.
