[Expression of Concern] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Chen,Jin-Long; Chen,Fang; Zhang,Ting-Ting; Liu,Nai-Fu

doi:10.3892/ijmm.2025.5627

November-2025 Volume 56 Issue 5

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November-2025 Volume 56 Issue 5

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Expression of Concern Open Access

[Expression of Concern] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Authors:
- Jin-Long Chen
- Fang Chen
- Ting-Ting Zhang
- Nai-Fu Liu
View Affiliations / Copyright

Affiliations: School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. China, Wei Fang People's Hospital, Weifang, Shandong 261100, P.R. China, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. China

Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 186
|
Published online on: September 4, 2025

https://doi.org/10.3892/ijmm.2025.5627
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Abstract

Following the publication of this paper, for the western blots shown in Fig. 1A, where the expression levels of salt‑inducible kinase 1 were detected in ovarian cancer tissues, it was drawn to the Editor's attention by a concerned reader that the β‑actin loading controls for patients 4, 6 and 7 were strikingly similar in appearance. Moreover, several of the protein bands in this figure were strikingly similar to data which subsequently appeared in another paper written by different authors at different research institutes that was published in the journal Experimental and Therapeutic Medicine, although this paper has since been retracted. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper, although up to this time, no response from the authors has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [International Journal of Molecular Medicine 37: 1601‑1610, 2016; DOI: 10.3892/ijmm.2016.2553]

Int J Mol Med 37: [Related article:] 1601-1610, 2016; DOI: 10.3892/ijmm.2016.2553

Following the publication of this paper, for the western blots shown in Fig. 1A, where the expression levels of salt-inducible kinase 1 were detected in ovarian cancer tissues, it was drawn to the Editor's attention by a concerned reader that the β-actin loading controls for patients 4, 6 and 7 were strikingly similar in appearance. Moreover, several of the protein bands in this figure were strikingly similar to data which subsequently appeared in another paper written by different authors at different research institutes that was published in the journal Experimental and Therapeutic Medicine, although this paper has since been retracted.

The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper, although up to this time, no response from the authors has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Expression of Concern] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

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Abstract

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