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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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February-2026 Volume 57 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

  • Authors:
    • Wanmeng Chen
    • Yujiu Ma
    • Xudong Zhang
    • Siwen Zhang
    • Shanshan Wu
    • Yimeng Lu
    • Jichun Tan

  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Center of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110022, P.R. China
  • Article Number: 32
    |
    Published online on: December 1, 2025
       https://doi.org/10.3892/ijmm.2025.5703
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Abstract

Endometriosis is a complex, chronic inflammatory gynecological disorder with estrogen‑dependent characteristics that severely impairs the quality of life of women and potentially leads to infertility. However, its pathogenesis remains poorly understood. Exosomes, small, discoid vesicles released by nearly all cell types, serve essential functions in multiple biological processes, including immune evasion, cellular migration, and differentiation. These vesicles can transport a broad repertoire of bioactive molecules, cross cell membranes readily, and remain stable within cells and body fluids. The present review summarizes global research from the last two decades on the mechanistic associations between exosomes and endometriosis, emphasizing their potential as vehicles for therapeutic delivery. Notably, the biological hallmarks of endometriosis such as fibrosis, immune dysregulation, angiogenesis, and aberrant cellular proliferation and migration, align with exosomal functions, suggesting that exosomes may contribute to disease progression. Furthermore, the use of exosomes as natural carriers for endometriosis treatment has been proposed, suggesting novel therapeutic avenues.

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Copy and paste a formatted citation
Spandidos Publications style
Chen W, Ma Y, Zhang X, Zhang S, Wu S, Lu Y and Tan J: Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review). Int J Mol Med 57: 32, 2026.
APA
Chen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., & Tan, J. (2026). Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review). International Journal of Molecular Medicine, 57, 32. https://doi.org/10.3892/ijmm.2025.5703
MLA
Chen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., Tan, J."Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)". International Journal of Molecular Medicine 57.2 (2026): 32.
Chicago
Chen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., Tan, J."Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)". International Journal of Molecular Medicine 57, no. 2 (2026): 32. https://doi.org/10.3892/ijmm.2025.5703
Copy and paste a formatted citation
x
Spandidos Publications style
Chen W, Ma Y, Zhang X, Zhang S, Wu S, Lu Y and Tan J: Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review). Int J Mol Med 57: 32, 2026.
APA
Chen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., & Tan, J. (2026). Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review). International Journal of Molecular Medicine, 57, 32. https://doi.org/10.3892/ijmm.2025.5703
MLA
Chen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., Tan, J."Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)". International Journal of Molecular Medicine 57.2 (2026): 32.
Chicago
Chen, W., Ma, Y., Zhang, X., Zhang, S., Wu, S., Lu, Y., Tan, J."Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)". International Journal of Molecular Medicine 57, no. 2 (2026): 32. https://doi.org/10.3892/ijmm.2025.5703
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