|
1
|
Lane NE: Epidemiology, etiology, and
diagnosis of osteoporosis. Am J Obstet Gynecol. 194(2 Suppl):
S3–S11. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kendler DL, Marin F, Zerbini C, Russo LA,
Greenspan SL, Zikan V, Bagur A, Malouf-Sierra J, Lakatos P,
Fahrleitner-Pammer A, et al: Effects of teriparatide and
risedronate on new fractures in post-menopausal women with severe
osteoporosis (VERO): A multicentre, double-blind, double-dummy,
randomised controlled trial. Lancet. 391:230–240. 2018. View Article : Google Scholar
|
|
3
|
Zhang YW, Song PR, Wang SC, Liu H, Shi ZM
and Su JC: Diets intervene osteoporosis via gut-bone axis. Gut
Microbes. 16:22954322024. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Inoue S, Hatakeyama J, Aoki H, Kuroki H,
Niikura T, Oe K, Fukui T, Kuroda R, Akisue T and Moriyama H:
Effects of ultrasound, radial extracorporeal shock waves, and
electrical stimulation on rat bone defect healing. Ann N Y Acad
Sci. 1497:3–14. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Fuggle N, Laslop A, Rizzoli R, Al-Daghri
N, Alokail M, Balkowiec-Iskra E, Beaudart C, Bruyère O, Bemden AB,
Burlet N, et al: Treatment of osteoporosis and osteoarthritis in
the oldest old. Drugs. 85:343–360. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Eastell R, Rosen CJ, Black DM, Cheung AM,
Murad MH and Shoback D: Pharmacological management of osteoporosis
in postmenopausal women: An Endocrine Society* clinical practice
guideline. J Clin Endocrinol Metab. 104:1595–1622. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Chen ZH, Wu JJ, Guo DY, Li YY, Chen MN,
Zhang ZY, Yuan ZD, Zhang KW, Chen WW, Tian F, et al: Physiological
functions of podosomes: From structure and function to therapy
implications in osteoclast biology of bone resorption. Ageing Res
Rev. 85:1018422023. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Heffler E, Madeira L, Ferrando M, Puggioni
F, Racca F, Malvezzi L, Passalacqua G and Canonica GW: Inhaled
corticosteroids safety and adverse effects in patients with asthma.
J Allergy Clin Immunol Pract. 6:776–781. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Hesari E, Sanjari M, Mansourzadeh MJ,
Fahimfar N, Khalagi K, Ghazbani A, Ostovar A and Fotouhi A:
Osteoporosis medication adherence tools: A systematic review.
Osteoporos Int. 34:1535–1548. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Waldbaum J, Xhumari J, Akinsuyi OS,
Arjmandi B, Anton S and Roesch L: Association between dysbiosis in
the gut microbiota of primary osteoporosis patients and bone loss.
Aging Dis. 14:2081–2095. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li Y, Yang P, Ye J, Xu Q, Wu J and Wang Y:
Updated mechanisms of MASLD pathogenesis. Lipids Health Dis.
23:1172024. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Tang WH, Kitai T and Hazen SL: Gut
microbiota in cardiovascular health and disease. Circ Res.
120:1183–1196. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Tao H, Li W, Zhang W, Yang C, Zhang C,
Liang X, Yin J, Bai J, Ge G, Zhang H, et al: Urolithin A suppresses
RANKL-induced osteoclastogenesis and postmenopausal osteoporosis
by, suppresses inflammation and downstream NF-κB activated
pyroptosis pathways. Pharmacol Res. 174:1059672021. View Article : Google Scholar
|
|
14
|
Jiang T, Yang X, Wu B, Tao R, Chen R, Jin
L, Sun D and Weng H: Gut microbiota in hypothyroidism: Pathogenic
mechanisms and opportunities for precision microbiome
interventions. Front Microbiol. 16:16612112025. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Xie X, Song J, Wu Y, Li M, Guo W, Li S and
Li Y: Study on gut microbiota and metabolomics in postmenopausal
women. BMC Womens Health. 24:6082024. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Birg A and Lin HC: The role of
bacteria-derived hydrogen sulfide in multiple axes of disease. Int
J Mol Sci. 26:33402025. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Akinsuyi OS and Roesch L: Meta-analysis
reveals compositional and functional microbial changes associated
with osteoporosis. Microbiol Spectr. 11:e00322232023. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Liu JH, Chen CY, Liu ZZ, Luo ZW, Rao SS,
Jin L, Wan TF, Yue T, Tan YJ, Yin H, et al: Extracellular vesicles
from child gut microbiota enter into bone to preserve bone mass and
strength. Adv Sci (Weinh). 8:20048312021. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Li JY, Chassaing B, Tyagi AM, Vaccaro C,
Luo T, Adams J, Darby TM, Weitzmann MN, Mulle JG, Gewirtz AT, et
al: Sex steroid deficiency-associated bone loss is microbiota
dependent and prevented by probiotics. J Clin Invest.
126:2049–2063. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yu C, Sun R, Yang W, Gu T, Ying X, Ye L,
Zheng Y, Fan S, Zeng X and Yao S: Exercise ameliorates osteopenia
in mice via intestinal microbial-mediated bile acid metabolism
pathway. Theranostics. 15:1741–1759. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Inchingolo AM, Gargiulo Isacco C,
Inchingolo AD, Nguyen K, Cantore S, Santacroce L, Scacco S, Cirulli
N, Corriero A, Puntillo F, et al: The human microbiota key role in
the bone metabolism activity. Eur Rev Med Pharmacol Sci.
27:2659–2670. 2023.PubMed/NCBI
|
|
22
|
Huang R, Liu P, Bai Y, Huang J, Pan R, Li
H, Su Y, Zhou Q, Ma R, Zong S, et al: Changes in the gut microbiota
of osteoporosis patients based on 16S rRNA gene sequencing: A
systematic review and meta-analysis. J Zhejiang Univ Sci B.
23:1002–1013. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Guadalupe-Grau A, Fuentes T, Guerra B and
Calbet JA: Exercise and bone mass in adults. Sports Med.
39:439–468. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang L, Zeng C, Huang J, Yan H, Jiang Y
and Li R: Exploration of the miR-187-3p/CNR2 pathway in modulating
osteoblast differentiation and treating postmenopausal osteoporosis
through mechanical stress. FASEB J. 38:e237762024. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Liao HW, Huang TH, Chang YH, Liou HH, Chou
YH, Sue YM, Hung PH, Chang YT, Ho PC and Tsai KJ: Exercise
alleviates osteoporosis in rats with mild chronic kidney disease by
decreasing sclerostin production. Int J Mol Sci. 20:20442019.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Gao Y, Wang H, Shi L, Cao M, Liu X, Zhang
Y, Chen X, Rong Y, Han B, Lu P, et al: Gut-bone axis mediates
exercise modality-dependent suppression of inflammatory
osteoclastogenesis in ovariectomy-induced bone loss. Mediators
Inflamm. 2025:57153322025. View Article : Google Scholar
|
|
27
|
Barcik W, Boutin R, Sokolowska M and
Finlay BB: The role of lung and gut microbiota in the pathology of
asthma. Immunity. 52:241–255. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Gillman SJ, McKenney EA and Lafferty D:
Wild black bears harbor simple gut microbial communities with
little difference between the jejunum and colon. Sci Rep.
10:207792020. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Oswald IP: Role of intestinal epithelial
cells in the innate immune defence of the pig intestine. Vet Res.
37:359–368. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Pedersini P, Turroni S and Villafañe JH:
Gut microbiota and physical activity: Is there an evidence-based
link. Sci Total Environ. 727:1386482020. View Article : Google Scholar
|
|
31
|
Fernandes I, Pérez-Gregorio R, Soares S,
Mateus N and de Freitas V: Wine flavonoids in health and disease
prevention. Molecules. 22:2922017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Bezirtzoglou E and Stavropoulou E:
Immunology and probiotic impact of the newborn and young children
intestinal microflora. Anaerobe. 17:369–374. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yang Y, Chen J, Gao H, Cui M, Zhu M, Xiang
X and Wang Q: Characterization of the gut microbiota and fecal and
blood metabolomes under various factors in urban children from
Northwest China. Front Cell Infect Microbiol. 14:13745442024.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zang Y, Lai X, Li C, Ding D, Wang Y and
Zhu Y: The Role of gut microbiota in various neurological and
psychiatric disorders-an evidence mapping based on quantified
evidence. Mediators Inflamm. 2023:51271572023. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Heravi FS, Naseri K and Hu H: Gut
Microbiota composition in patients with neurodegenerative disorders
(Parkinson's and Alzheimer's) and healthy controls: A systematic
review. Nutrients. 15:43652023. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Singhal R, Donde H, Ghare S, Stocke K,
Zhang J, Vadhanam M, Reddy S, Gobejishvili L, Chilton P,
Joshi-Barve S, et al: Decrease in acetyl-CoA pathway utilizing
butyrate-producing bacteria is a key pathogenic feature of
alcohol-induced functional gut microbial dysbiosis and development
of liver disease in mice. Gut Microbes. 13:19463672021. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Xing P, Hahnke RL, Unfried F, Markert S,
Huang S, Barbeyron T, Harder J, Becher D, Schweder T, Glöckner FO,
et al: Niches of two polysaccharide-degrading Polaribacter isolates
from the North Sea during a spring diatom bloom. ISME J.
9:1410–1422. 2015. View Article : Google Scholar
|
|
38
|
Pacoud M, Mandon K, Cazareth J, Pierre O,
Frendo P and Alloing G: Redox-sensitive fluorescent biosensors
detect Sinorhizobium meliloti intracellular redox changes under
free-living and symbiotic lifestyles. Free Radic Biol Med.
184:185–195. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Dierick M, Ongena R, Vanrompay D,
Devriendt B and Cox E: Exploring the modulatory role of bovine
lactoferrin on the microbiome and the immune response in healthy
and Shiga toxin-producing E. coli challenged weaned piglets. J Anim
Sci Biotechnol. 15:392024. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kang EJ, Kim JH, Kim YE, Lee H, Jung KB,
Chang DH, Lee Y, Park S, Lee EY, Lee EJ, et al: The secreted
protein Amuc_1409 from Akkermansia muciniphila improves gut health
through intestinal stem cell regulation. Nat Commun. 15:29832024.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Thacharodi A, Hassan S, Ahmed Z, Singh P,
Maqbool M, Meenatchi R, Pugazhendhi A and Sharma A: The ruminant
gut microbiome vs enteric methane emission: The essential microbes
may help to mitigate the global methane crisis. Environ Res.
261:1196612024. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Gao Z, Kang Y, Yu J and Ren L: Human
pharyngeal microbiome may play a protective role in respiratory
tract infections. Genomics Proteomics Bioinformatics. 12:144–150.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Hu Q, Huang L, Yang Y, Xiang Y and Liu J:
Essential phage component induces resistance of bacterial
community. Sci Adv. 10:eadp50572024. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Kaye DM, Shihata WA, Jama HA, Tsyganov K,
Ziemann M, Kiriazis H, Horlock D, Vijay A, Giam B, Vinh A, et al:
Deficiency of prebiotic fiber and insufficient signaling through
gut metabolite-sensing receptors leads to cardiovascular disease.
Circulation. 141:1393–1403. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ridlon JM, Harris SC, Bhowmik S, Kang DJ
and Hylemon PB: Consequences of bile salt biotransformations by
intestinal bacteria. Gut Microbes. 7:22–39. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Ma L, Ni Y, Wang Z, Tu W, Ni L, Zhuge F,
Zheng A, Hu L, Zhao Y, Zheng L, et al: Spermidine improves gut
barrier integrity and gut microbiota function in diet-induced obese
mice. Gut Microbes. 12:1–19. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Lalonde R and Strazielle C: Probiotic
effects on anxiety-like behavior in animal models. Rev Neurosci.
33:691–701. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Wan C, Liu ZB, Tan H, Zhang Z, Zhou Q, Yao
LH, Meng W and Wang S: Effect of voluntary wheel running on gut
microbiota composition in developing mice. Nutr Hosp. 39:896–904.
2022.PubMed/NCBI
|
|
49
|
Leigh SJ, Kaakoush NO, Escorihuela RM,
Westbrook RF and Morris MJ: Treadmill exercise has minimal impact
on obesogenic diet-related gut microbiome changes but alters
adipose and hypothalamic gene expression in rats. Nutr Metab
(Lond). 17:712020. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Hendesi H, Godfrey DA, Ruble AF, Tran AM,
Villani DA, Landgrave SH, Hasan NA, Adams DJ and Zuscik MJ:
Intermittent fasting alleviates obesity-associated impairments in
bone fracture healing: Exploring the role of gut microbiome. Bone
Rep. 27:1018762025. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Okoro PC, Orwoll ES, Huttenhower C, Morgan
X, Kuntz TM, McIver LJ, Dufour AB, Bouxsein ML, Langsetmo L,
Farsijani S, et al: A two-cohort study on the association between
the gut microbiota and bone density, microarchitecture, and
strength. Front Endocrinol (Lausanne). 14:12377272023. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Barbu AC, Stoleru S, Zugravu A, Poenaru E,
Dragomir A, Costescu M, Aurelian SM, Shhab Y, Stoleru CM, Coman OA,
et al: Dopamine and the gut Microbiota: Interactions within the
Microbiota-gut-brain axis and therapeutic perspectives. Int J Mol
Sci. 27:2712025. View Article : Google Scholar
|
|
53
|
Ren H, Wen J, Liu J and Wang L: Gut
microbiota in immunomodulation and infection prevention among
multiple myeloma patients after chemotherapy: Current evidence and
clinical prospects. Am J Cancer Res. 15:4621–4638. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Kawaratani H, Moriya K, Namisaki T, Uejima
M, Kitade M, Takeda K, Okura Y, Kaji K, Takaya H, Nishimura N, et
al: Therapeutic strategies for alcoholic liver disease: Focusing on
inflammation and fibrosis (Review). Int J Mol Med. 40:263–270.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Zhao Z, Ning J, Bao XQ, Shang M, Ma J, Li
G and Zhang D: Fecal microbiota transplantation protects
rotenone-induced Parkinson's disease mice via suppressing
inflammation mediated by the lipopolysaccharide-TLR4 signaling
pathway through the microbiota-gut-brain axis. Microbiome.
9:2262021. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Yokota K, Sato K, Miyazaki T, Aizaki Y,
Tanaka S, Sekikawa M, Kozu N, Kadono Y, Oda H and Mimura T:
Characterization and function of tumor necrosis factor and
interleukin-6-induced osteoclasts in rheumatoid arthritis.
Arthritis Rheumatol. 73:1145–1154. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Yin Y, Sichler A, Ecker J, Laschinger M,
Liebisch G, Höring M, Basic M, Bleich A, Zhang XJ, Kübelsbeck L, et
al: Gut microbiota promote liver regeneration through hepatic
membrane phospholipid biosynthesis. J Hepatol. 78:820–835. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Liu YJ, Tang B, Wang FC, Tang L, Lei YY,
Luo Y, Huang SJ, Yang M, Wu LY, Wang W, et al: Parthenolide
ameliorates colon inflammation through regulating Treg/Th17 balance
in a gut microbiota-dependent manner. Theranostics. 10:5225–5241.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Montalvany-Antonucci CC, Duffles LF, de
Arruda J, Zicker MC, de Oliveira S, Macari S, Garlet GP, Madeira M,
Fukada SY, Andrade I, et al: Short-chain fatty acids and FFAR2 as
suppressors of bone resorption. Bone. 125:112–121. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Song C, Yan Q, Ma Y, Li P, Yang Y, Wang Y,
Li W, Wan X, Li Y, Zhu R, et al: Modified Zuo Gui wan ameliorates
ovariectomy-induced osteoporosis in rats by regulating the
SCFA-GPR41-p38MAPK signaling pathway. Drug Des Devel Ther.
18:6359–6377. 2024. View Article : Google Scholar :
|
|
61
|
Carson MD, Warner AJ, Hathaway-Schrader
JD, Geiser VL, Kim J, Gerasco JE, Hill WD, Lemasters JJ,
Alekseyenko AV, Wu Y, et al: Minocycline-induced disruption of the
intestinal FXR/FGF15 axis impairs osteogenesis in mice. JCI
Insight. 8:e1605782023. View Article : Google Scholar :
|
|
62
|
Lyu Y, Hu J, Wang X, Zhang J, Li X, Cui M,
Tang X and Zhou P: Lactopontin regulates gut microbiota and calcium
absorption to promote bone growth in growing rats. Int J Biol
Macromol. 302:1405572025. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Yan J, Herzog JW, Tsang K, Brennan CA,
Bower MA, Garrett WS, Sartor BR, Aliprantis AO and Charles JF: Gut
microbiota induce IGF-1 and promote bone formation and growth. Proc
Natl Acad Sci USA. 113:E7554–E7563. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Chen Q, Shou P, Zheng C, Jiang M, Cao G,
Yang Q, Cao J, Xie N, Velletri T, Zhang X, et al: Fate decision of
mesenchymal stem cells: Adipocytes or osteoblasts. Cell Death
Differ. 23:1128–1139. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Shay JW, Homma N, Zhou R, Naseer MI,
Chaudhary AG, Al-Qahtani M, Hirokawa N, Goudarzi M, Fornace AJ Jr,
Baeesa S, et al: Abstracts from the 3rd International Genomic
Medicine Conference (3rd IGMC 2015): Jeddah, Kingdom of Saudi
Arabia. 30 November-3 December 2015. BMC Genomics. 17(Suppl 6):
S4872016. View Article : Google Scholar
|
|
66
|
Liu A, Liang X, Wang W, Wang C, Song J,
Guo J, Sun D, Wang D, Song M, Qian J, et al: Human umbilical cord
mesenchymal stem cells ameliorate colon inflammation via modulation
of gut microbiota-SCFAs-immune axis. Stem Cell Res Ther.
14:2712023. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Hao H, Liu Q, Zheng T, Li J, Zhang T, Yao
Y, Liu Y, Lin K, Liu T, Gong P, et al: Oral Milk-derived
extracellular vesicles inhibit osteoclastogenesis and ameliorate
bone loss in ovariectomized mice by improving gut microbiota. J
Agric Food Chem. 72:4726–4736. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Wei F, Hughes M, Omer M, Ngo C,
Pugazhendhi AS, Kolanthai E, Aceto M, Ghattas Y, Razavi M, Kean TJ,
et al: A multifunctional therapeutic strategy using P7C3 as A
countermeasure against bone loss and fragility in an ovariectomized
rat model of postmenopausal osteoporosis. Adv Sci (Weinh).
11:e23086982024. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Ding K, Hua F and Ding W: Gut microbiome
and osteoporosis. Aging Dis. 11:438–447. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Xiao L, Zhou Y, Bokoliya S, Lin Q and
Hurley M: Bone loss is ameliorated by fecal microbiota
transplantation through SCFA/GPR41/IGF1 pathway in sickle cell
disease mice. Sci Rep. 12:206382022. View Article : Google Scholar
|
|
71
|
Li Z, Huang J, Wang F, Li W, Wu X, Zhao C,
Zhao J, Wei H, Wu Z, Qian M, et al: Dual targeting of bile acid
receptor-1 (TGR5) and Farnesoid X receptor (FXR) prevents
estrogen-dependent bone loss in mice. J Bone Miner Res. 34:765–776.
2019. View Article : Google Scholar
|
|
72
|
Wang Q, Wang G, Wang B and Yang H:
Activation of TGR5 promotes osteoblastic cell differentiation and
mineralization. Biomed Pharmacother. 108:1797–1803. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Cho SW, An JH, Park H, Yang JY, Choi HJ,
Kim SW, Park YJ, Kim SY, Yim M, Baek WY, et al: Positive regulation
of osteogenesis by bile acid through FXR. J Bone Miner Res.
28:2109–2121. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Zhu L, Hua F, Ding W, Ding K, Zhang Y and
Xu C: The correlation between the Th17/Treg cell balance and bone
health. Immun Ageing. 17:302020. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Sun P, Zhang C, Huang Y, Yang J, Zhou F,
Zeng J and Lin Y: Jiangu granule ameliorated OVX rats bone loss by
modulating gut microbiota-SCFAs-Treg/Th17 axis. Biomed
Pharmacother. 150:1129752022. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Liu S, Li G, Xu H, Wang Q, Wei Y, Yang Q,
Xiong A, Yu F, Weng J and Zeng H: 'Cross-talk' between gut
microbiome dysbiosis and osteoarthritis progression: A systematic
review. Front Immunol. 14:11505722023. View Article : Google Scholar
|
|
77
|
Li C, Huang Q, Yang R, Dai Y, Zeng Y, Tao
L, Li X, Zeng J and Wang Q: Gut microbiota composition and bone
mineral loss-epidemiologic evidence from individuals in Wuhan,
China. Osteoporos Int. 30:1003–1013. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Fata JE, Kong YY, Li J, Sasaki T,
Irie-Sasaki J, Moorehead RA, Elliott R, Scully S, Voura EB, Lacey
DL, et al: The osteoclast differentiation factor
osteoprotegerin-ligand is essential for mammary gland development.
Cell. 103:41–50. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Han D, Wang W, Gong J, Ma Y and Li Y:
Microbiota metabolites in bone: Shaping health and confronting
disease. Heliyon. 10:e284352024. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Wang N, Hao Y and Fu L:
Trimethylamine-N-Oxide promotes osteoclast differentiation and bone
loss via activating ROS-dependent NF-κB signaling pathway.
Nutrients. 14:39552022. View Article : Google Scholar
|
|
81
|
Zhao Y, Wang C, Qiu F, Liu J, Xie Y, Lin
Z, He J and Chen J: Trimethylamine-N-oxide promotes osteoclast
differentiation and oxidative stress by activating NF-κB pathway.
Aging (Albany NY). 16:9251–9263. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Feng R, Wang Q, Yu T, Hu H, Wu G, Duan X,
Jiang R, Xu Y and Huang Y: Quercetin ameliorates bone loss in OVX
rats by modulating the intestinal flora-SCFAs-inflammatory
signaling axis. Int Immunopharmacol. 136:1123412024. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Liu T, Yu H, Wang S, Li H, Du X and He X:
Chondroitin sulfate alleviates osteoporosis caused by calcium
deficiency by regulating lipid metabolism. Nutr Metab (Lond).
20:62023. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Li K, Liu A, Zong W, Dai L, Liu Y, Luo R,
Ge S and Dong G: Moderate exercise ameliorates osteoarthritis by
reducing lipopolysaccharides from gut microbiota in mice. Saudi J
Biol Sci. 28:40–49. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Yang X, Wang Y, Han X, Shu R, Chen T, Zeng
H, Xu X, Huang L, Ren A, Song J, et al: Effects of TGF-β1 on
OPG/RANKL expression of cementoblasts and osteoblasts are similar
without stress but different with mechanical compressive stress.
ScientificWorldJournal. 2015:7181802015. View Article : Google Scholar
|
|
86
|
Guo M, Liu H, Yu Y, Zhu X, Xie H, Wei C,
Mei C, Shi Y, Zhou N, Qin K, et al: Lactobacillus rhamnosus GG
ameliorates osteoporosis in ovariectomized rats by regulating the
Th17/Treg balance and gut microbiota structure. Gut Microbes.
15:21903042023. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Hu H, Yao Y, Liu F, Luo L, Liu J, Wang X
and Wang Q: Integrated microbiome and metabolomics revealed the
protective effect of baicalin on alveolar bone inflammatory
resorption in aging. Phytomedicine. 124:1552332024. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Beaudart C, Dawson A, Shaw SC, Harvey NC,
Kanis JA, Binkley N, Reginster JY, Chapurlat R, Chan DC, Bruyère O,
et al: Nutrition and physical activity in the prevention and
treatment of sarcopenia: Systematic review. Osteoporos Int.
28:1817–1833. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Angulo J, El Assar M, Álvarez-Bustos A and
Rodríguez-Mañas L: Physical activity and exercise: Strategies to
manage frailty. Redox Biol. 35:1015132020. View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Lucas S, Omata Y, Hofmann J, Böttcher M,
Iljazovic A, Sarter K, Albrecht O, Schulz O, Krishnacoumar B,
Krönke G, et al: Short-chain fatty acids regulate systemic bone
mass and protect from pathological bone loss. Nat Commun. 9:552018.
View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Li X, Han Y, Guan Y, Zhang L, Bai C and Li
Y: Aluminum induces osteoblast apoptosis through the oxidative
stress-mediated JNK signaling pathway. Biol Trace Elem Res.
150:502–508. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Ding M, Li B, Chen H, Liang D, Ross RP,
Stanton C, Zhao J, Chen W and Yang B: Human breastmilk-derived
Bifidobacterium longum subsp. infantis CCFM1269 regulates bone
formation by the GH/IGF axis through PI3K/AKT pathway. Gut
Microbes. 16:22903442024. View Article : Google Scholar :
|
|
93
|
Guan Z, Xiao W, Guan Z, Xiao J, Jin X, Liu
S, Qin Y and Luo L: Intermittent fasting triggers interorgan
communication to improve the progression of diabetic osteoporosis.
Gut Microbes. 17:25556192025. View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Li R, Miao Z, Liu Y, Chen X, Wang H, Su J
and Chen J: The brain-gut-bone axis in neurodegenerative diseases:
Insights, challenges, and future prospects. Adv Sci (Weinh).
11:e23079712024. View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Lorenzo D, GianVincenzo Z, Carlo Luca R,
Karan G, Jorge V, Roberto M and Javad P: Oral-gut microbiota and
arthritis: Is there an evidence-based axis. J Clin Med.
8:02019.
|
|
96
|
Wu M, Chen C, Lei H, Cao Z, Zhang C, Du R,
Zhang C, Song Y, Qin M, Zhou J, et al: Dietary isoquercetin
ameliorates bone loss via restoration of the gut microbiota and
lipopolysaccharide-triggered inflammatory status in ovariectomy
mice. J Agric Food Chem. 71:15981–15990. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Li H, Hu S, Wu R, Zhou H, Zhang K, Li K,
Lin W, Shi Q, Chen H and Lv S: 11β-Hydroxysteroid dehydrogenase
type 1 facilitates osteoporosis by turning on Osteoclastogenesis
through Hippo Signaling. Int J Biol Sci. 19:3628–3639. 2023.
View Article : Google Scholar
|
|
98
|
Bai J, Si G, Wang R, Su S, Fan J, He X, Lv
Y, Gao S and Zhou F: Gut metabolite indoleacrylic acid suppresses
osteoclast formation by AHR mediated NF-κB signaling pathway. Int J
Biol Sci. 22:951–969. 2026. View Article : Google Scholar
|
|
99
|
Chen Y, Yang C, Dai Q, Tan J, Dou C and
Luo F: Gold-nanosphere mitigates osteoporosis through regulating
TMAO metabolism in a gut microbiota-dependent manner. J
Nanobiotechnology. 21:1252023. View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Yadav S, Sapra L and Srivastava RK:
Polysaccharides to postbiotics: Nurturing bone health via
modulating 'gut-immune axis'. Int J Biol Macromol. 278:1346552024.
View Article : Google Scholar
|
|
101
|
Czernik PJ, Golonka RM, Chakraborty S,
Yeoh BS, Abokor AA, Saha P, Yeo JY, Mell B, Cheng X, Baroi S, et
al: Reconstitution of the host holobiont in germ-free born male
rats acutely increases bone growth and affects marrow cellular
content. Physiol Genomics. 53:518–533. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Liu Y, Guo YL, Meng S, Gao H, Sui LJ, Jin
S, Li Y and Fan SG: Gut microbiota-dependent Trimethylamine N-Oxide
are related with hip fracture in postmenopausal women: A matched
case-control study. Aging (Albany NY). 12:10633–10641. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Zhao YX, Song YW, Zhang L, Zheng FJ, Wang
XM, Zhuang XH, Wu F and Liu J: Association between bile acid
metabolism and bone mineral density in postmenopausal women.
Clinics (Sao Paulo). 75:e14862020. View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Schwarzer M, Makki K, Storelli G,
Machuca-Gayet I, Srutkova D, Hermanova P, Martino ME, Balmand S,
Hudcovic T, Heddi A, et al: Lactobacillus plantarum strain
maintains growth of infant mice during chronic undernutrition.
Science. 351:854–857. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
105
|
Quach D, Collins F, Parameswaran N, McCabe
L and Britton RA: Microbiota reconstitution does not cause bone
loss in germ-free mice. mSphere. 3:e00545–00517. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
106
|
Li Z, Wang Q, Huang X, Wu Y and Shan D:
Microbiome's role in musculoskeletal health through the gut-bone
axis insights. Gut Microbes. 16:24104782024. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Sjögren K, Engdahl C, Henning P, Lerner
UH, Tremaroli V, Lagerquist MK, Bäckhed F and Ohlsson C: The gut
microbiota regulates bone mass in mice. J Bone Miner Res.
27:1357–1367. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
108
|
Hartmann K, Lenz A, Letko G, Schulz HU,
Sokolowski A, Spormann H and Zühlke H: Isolated cells in suspension
for biological research-Part II. Structure and functional
properties of cells from pancreatic islets and acini. Exp Pathol.
34:1–22. 1988. View Article : Google Scholar
|
|
109
|
Lin H, Liu T, Li X, Gao X, Wu T and Li P:
The role of gut microbiota metabolite trimethylamine N-oxide in
functional impairment of bone marrow mesenchymal stem cells in
osteoporosis disease. Ann Transl Med. 8:10092020. View Article : Google Scholar : PubMed/NCBI
|
|
110
|
Chen CY, Rao SS, Yue T, Tan YJ, Yin H,
Chen LJ, Luo MJ, Wang Z, Wang YY, Hong CG, et al:
Glucocorticoid-induced loss of beneficial gut bacterial
extracellular vesicles is associated with the pathogenesis of
osteonecrosis. Sci Adv. 8:eabg83352022. View Article : Google Scholar : PubMed/NCBI
|
|
111
|
Wu Z, Chen J, Kong F, Zhang Y, Yi J, Li Y,
Hu M and Wang D: Polypeptide of Inonotus hispidus extracts
alleviates periodontitis through suppressing inflammatory bone
loss. Int J Biol Macromol. 287:1383502025. View Article : Google Scholar
|
|
112
|
Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama
N, Yu XN, Kubo C and Koga Y: Postnatal microbial colonization
programs the hypothalamic-pituitary-adrenal system for stress
response in mice. J Physiol. 558:263–275. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
113
|
Cooper MS: Sensitivity of bone to
glucocorticoids. Clin Sci (Lond). 107:111–123. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
114
|
Zhou RX, Zhang YW, Cao MM, Liu CH, Rui YF
and Li YJ: Linking the relation between gut microbiota and
glucocorticoid-induced osteoporosis. J Bone Miner Metab.
41:145–162. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
115
|
Hong S, Cha KH, Park JH, Jung DS, Choi JH,
Yoo G and Nho CW: Cinnamic acid suppresses bone loss via induction
of osteoblast differentiation with alteration of gut microbiota. J
Nutr Biochem. 101:1089002022. View Article : Google Scholar
|
|
116
|
Dong J, Shu G, Yang J, Wang B, Chen L,
Gong Z and Zhang X: Mechanistic study on the alleviation of
postmenopausal osteoporosis by Lactobacillus acidophilus through
butyrate-mediated inhibition of osteoclast activity. Sci Rep.
14:70422024. View Article : Google Scholar : PubMed/NCBI
|
|
117
|
Li JY, Yu M, Pal S, Tyagi AM, Dar H, Adams
J, Weitzmann MN, Jones RM and Pacifici R: Parathyroid
hormone-dependent bone formation requires butyrate production by
intestinal microbiota. J Clin Invest. 130:1767–1781. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
118
|
Hu HT, Zhang ZY, Luo Z, Ti HB, Wu JJ, Nie
H, Yuan ZD, Wu X, Zhang KY, Shi SW, et al: Emerging regulated cell
death mechanisms in bone remodeling: Decoding ferroptosis,
cuproptosis, disulfidptosis, and PANoptosis as therapeutic targets
for skeletal. Cell Death Discov. 11:3352025. View Article : Google Scholar
|
|
119
|
Xiao HH, Zhu YX, Lu L, Zhou LP, Poon CC,
Chan CO, Wang LJ, Cao S, Yu WX, Wong KY, et al: The Lignan-rich
fraction from sambucus williamsii hance exerts bone protective
effects via altering circulating serotonin and gut microbiota in
rats. Nutrients. 14:47182022. View Article : Google Scholar : PubMed/NCBI
|
|
120
|
Wei X, Yang X, Han ZP, Qu FF, Shao L and
Shi YF: Mesenchymal stem cells: A new trend for cell therapy. Acta
Pharmacol Sin. 34:747–754. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
121
|
Ozasa R, Matsugaki A, Isobe Y, Saku T, Yun
HS and Nakano T: Construction of human induced pluripotent stem
cell-derived oriented bone matrix microstructure by using in vitro
engineered anisotropic culture model. J Biomed Mater Res A.
106:360–369. 2018. View Article : Google Scholar :
|
|
122
|
Xing J, Ying Y, Mao C, Liu Y, Wang T, Zhao
Q, Zhang X, Yan F and Zhang H: Hypoxia induces senescence of bone
marrow mesenchymal stem cells via altered gut microbiota. Nat
Commun. 9:20202018. View Article : Google Scholar : PubMed/NCBI
|
|
123
|
Li W, Li T, Tang Z, Qi X, Zhou Y, Tang X,
Xu W and Xiong H: Taohong Siwu decoction promotes the process of
fracture healing by activating the VEGF-FAK signal pathway and
systemically regulating the gut microbiota. J Appl Microbiol.
133:1363–1377. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
124
|
Queipo-Ortuño MI, Seoane LM, Murri M,
Pardo M, Gomez-Zumaquero JM, Cardona F, Casanueva F and Tinahones
FJ: Gut microbiota composition in male rat models under different
nutritional status and physical activity and its association with
serum leptin and ghrelin levels. PLoS One. 8:e654652013. View Article : Google Scholar : PubMed/NCBI
|
|
125
|
Wang D, Cai J, Pei Q, Yan Z, Zhu F, Zhao
Z, Liu R, Guo X, Sun T, Liu J, et al: Gut microbial alterations in
arginine metabolism determine bone mechanical adaptation. Cell
Metab. 36:1252–1268.e8. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
126
|
Ye X, Sun P, Lao S, Wen M, Zheng R, Lin Y,
Gan L, Fan X, Wang P, Li Z, et al: Fgf21-dubosiella axis mediates
the protective effects of exercise against NAFLD development. Life
Sci. 334:1222312023. View Article : Google Scholar : PubMed/NCBI
|
|
127
|
Lambert JE, Myslicki JP, Bomhof MR, Belke
DD, Shearer J and Reimer RA: Exercise training modifies gut
microbiota in normal and diabetic mice. Appl Physiol Nutr Metab.
40:749–752. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
128
|
Liu Z, Liu HY, Zhou H, Zhan Q, Lai W, Zeng
Q, Ren H and Xu D: Moderate-intensity exercise affects gut
microbiome composition and influences cardiac function in
myocardial infarction mice. Front Microbiol. 8:16872017. View Article : Google Scholar : PubMed/NCBI
|
|
129
|
Wang J, Zhang Q, Xia J and Sun H: Moderate
treadmill exercise modulates gut microbiota and improves intestinal
barrier in high-fat-diet-induced obese mice via the AMPK/CDX2
signaling pathway. Diabetes Metab Syndr Obes. 15:209–223. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
130
|
Estaki M, Pither J, Baumeister P, Little
JP, Gill SK, Ghosh S, Ahmadi-Vand Z, Marsden KR and Gibson DL:
Cardiorespiratory fitness as a predictor of intestinal microbial
diversity and distinct metagenomic functions. Microbiome. 4:422016.
View Article : Google Scholar : PubMed/NCBI
|
|
131
|
Allen JM, Mailing LJ, Niemiro GM, Moore R,
Cook MD, White BA, Holscher HD and Woods JA: Exercise alters gut
microbiota composition and function in lean and obese humans. Med
Sci Sports Exerc. 50:747–757. 2018. View Article : Google Scholar
|
|
132
|
Barton W, Penney NC, Cronin O,
Garcia-Perez I, Molloy MG, Holmes E, Shanahan F, Cotter PD and
O'Sullivan O: The microbiome of professional athletes differs from
that of more sedentary subjects in composition and particularly at
the functional metabolic level. Gut. 67:625–633. 2018. View Article : Google Scholar
|
|
133
|
Motiani KK, Collado MC, Eskelinen JJ,
Virtanen KA, Löyttyniemi E, Salminen S, Nuutila P, Kalliokoski KK
and Hannukainen JC: Exercise training modulates gut microbiota
profile and improves endotoxemia. Med Sci Sports Exerc. 52:94–104.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
134
|
Wu J, Oka J, Higuchi M, Tabata I, Toda T,
Fujioka M, Fuku N, Teramoto T, Okuhira T, Ueno T, et al:
Cooperative effects of isoflavones and exercise on bone and lipid
metabolism in postmenopausal Japanese women: A randomized
placebo-controlled trial. Metabolism. 55:423–433. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
135
|
Lin Z, Zhang X, Wu M, Ming Y, Wang X, Li
H, Huang F, Gao F and Zhu Y: High-fiber diet and rope-skipping
benefit cardiometabolic health and modulate gut microbiota in young
adults: A randomized controlled trial. Food Res Int.
173:1134212023. View Article : Google Scholar : PubMed/NCBI
|
|
136
|
Zhang K, Guo H, Zhang X, Yang H, Yuan G,
Zhu Z, Lu X, Zhang J, Du J, Shi H, et al: Effects of aerobic
exercise or Tai Chi Chuan interventions on problematic mobile phone
use and the potential role of intestinal flora: A multi-arm
randomized controlled. J Psychiatr Res. 170:394–407. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
137
|
Wu WD, Wang Y and Wei JX: Effects of
MICT/HIIT on the ultrastructure of myocardium and soleus in rats
with high-fat diet and its mechanisms. Zhongguo Ying Yong Sheng Li
Xue Za Zhi. 38:708–713. 2022.In Chinese.
|
|
138
|
Castro AP, Silva KKS, Medeiros CSA, Alves
F, Araujo RC and Almeida JA: Effects of 12 weeks of resistance
training on rat gut microbiota composition. J Exp Biol.
224:jeb2425432021. View Article : Google Scholar
|
|
139
|
Wang L, Lavier J, Hua W, Wang Y, Gong L,
Wei H, Wang J, Pellegrin M, Millet GP and Zhang Y: High-intensity
interval training and moderate-intensity continuous training
attenuate oxidative damage and promote myokine response in the
skeletal muscle. Antioxidants (Basel). 10:9922021. View Article : Google Scholar
|
|
140
|
Denou E, Marcinko K, Surette MG, Steinberg
GR and Schertzer JD: High-intensity exercise training increases the
diversity and metabolic capacity of the mouse distal gut microbiota
during diet-induced obesity. Am J Physiol Endocrinol Metab.
310:E982–E993. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
141
|
Jäger R, Kerksick CM, Campbell BI, Cribb
PJ, Wells SD, Skwiat TM, Purpura M, Ziegenfuss TN, Ferrando AA,
Arent SM, et al: International society of sports nutrition position
stand: Protein and exercise. J Int Soc Sports Nutr. 14:202017.
View Article : Google Scholar : PubMed/NCBI
|
|
142
|
Donnelly JE, Blair SN, Jakicic JM, Manore
MM, Rankin JW and Smith BK; American College of Sports Medicine:
American College of Sports Medicine Position Stand. Appropriate
physical activity intervention strategies for weight loss and
prevention of weight regain for adults. Med Sci Sports Exerc.
41:459–471. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
143
|
Locatelli JC, Costa JG, Haynes A, Naylor
LH, Fegan PG, Yeap BB and Green DJ: Incretin-based weight loss
pharmacotherapy: Can resistance exercise optimize changes in body
composition. Diabetes Care. 47:1718–1730. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
144
|
Rettedal EA, Cree JME, Adams SE, MacRae C,
Skidmore PML, Cameron-Smith D, Gant N, Blenkiron C and Merry TL:
Short-term high-intensity interval training exercise does not
affect gut bacterial community diversity or composition of lean and
overweight men. Exp Physiol. 105:1268–1279. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
145
|
Hung WC, Hung WW, Tsai HJ, Chang CC, Chiu
YW, Hwang SJ, Kuo MC, Chen SC, Dai CY and Tsai YC: The association
of targeted gut microbiota with body composition in type 2 diabetes
mellitus. Int J Med Sci. 18:511–519. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
146
|
Mackay D, Mollard RC, Granger M, Bruce S,
Blewett H, Carlberg J, Duhamel T, Eck P, Faucher P, Hamm NC, et al:
The Manitoba personalized lifestyle research (TMPLR) study
protocol: A multicentre bidirectional observational cohort study
with administrative health record linkage investigating the
interactions between lifestyle and health in Manitoba, Canada. BMJ
Open. 9:e0233182019. View Article : Google Scholar : PubMed/NCBI
|
|
147
|
Nilsson AG, Sundh D, Bäckhed F and
Lorentzon M: Lactobacillus reuteri reduces bone loss in older women
with low bone mineral density: A randomized, placebo-controlled,
double-blind, clinical trial. J Intern Med. 284:307–317. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
148
|
Zhang C and Lin Y, Li H, Hu H, Chen Y,
Huang Y, Huang Z, Fang X, Zhang W and Lin Y: Fatty acid binding
protein 4 (FABP4) induces chondrocyte degeneration via activation
of the NF-κb signaling pathway. FASEB J. 38:e233472024. View Article : Google Scholar
|
|
149
|
Strasser B, Wolters M, Weyh C, Krüger K
and Ticinesi A: The effects of lifestyle and diet on gut microbiota
composition, inflammation and muscle performance in our aging
society. Nutrients. 13:20452021. View Article : Google Scholar : PubMed/NCBI
|
|
150
|
Zhang L, Wang P, Huang J, Xing Y, Wong FS,
Suo J and Wen L: Gut microbiota and therapy for obesity and type 2
diabetes. Front Endocrinol (Lausanne). 15:13337782024. View Article : Google Scholar : PubMed/NCBI
|
|
151
|
O'Brien MT, O'Sullivan O, Claesson MJ and
Cotter PD: The athlete gut microbiome and its relevance to health
and performance: A review. Sports Med. 52(Suppl 1): S119–S128.
2022. View Article : Google Scholar
|
|
152
|
Zhang Z, Liu L, Ti H, Chen M, Chen Y, Du
D, Zhan W, Wang T, Wu X, Wu J, et al: Synovial fibroblast derived
small extracellular vesicles miRNA15-29148 promotes articular
chondrocyte apoptosis in rheumatoid arthritis. Bone Res. 13:612025.
View Article : Google Scholar : PubMed/NCBI
|
|
153
|
Yuan Y, Yang J, Zhuge A, Li L and Ni S:
Gut microbiota modulates osteoclast glutathione synthesis and
mitochondrial biogenesis in mice subjected to ovariectomy. Cell
Prolif. 55:e131942022. View Article : Google Scholar : PubMed/NCBI
|
|
154
|
Desai S, Wu J, Horkeby K, Norgård M,
Ohlsson C, Windahl SH and Engdahl C: A COX-2 inhibitor does not
interfere with the bone-protective effects of loading in male mice
with arthritis. JBMR Plus. 7:e107512023. View Article : Google Scholar : PubMed/NCBI
|
|
155
|
Wang Q, Weng H, Xu Y, Ye H, Liang Y, Wang
L, Zhang Y, Gao Y, Wang J, Xu Y, et al: Anti-osteoporosis mechanism
of resistance exercise in ovariectomized rats based on
transcriptome analysis: A pilot study. Front Endocrinol (Lausanne).
14:11624152023. View Article : Google Scholar : PubMed/NCBI
|
|
156
|
McCabe LR, Irwin R, Tekalur A, Evans C,
Schepper JD, Parameswaran N and Ciancio M: Exercise prevents high
fat diet-induced bone loss, marrow adiposity and dysbiosis in male
mice. Bone. 118:20–31. 2019. View Article : Google Scholar
|
|
157
|
Yuan FL, Li X, Lu WG, Xu RS, Zhao YQ, Li
CW, Li JP and Chen FH: Regulatory T cells as a potent target for
controlling bone loss. Biochem Biophys Res Commun. 402:173–176.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
158
|
Li M, van Esch B, Wagenaar G, Garssen J,
Folkerts G and Henricks P: Pro- and anti-inflammatory effects of
short chain fatty acids on immune and endothelial cells. Eur J
Pharmacol. 831:52–59. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
159
|
Chen H, Shen L, Liu Y, Ma X, Long L, Ma X,
Ma L, Chen Z, Lin X, Si L and Chen X: Strength exercise confers
protection in central nervous system autoimmunity by altering the
gut microbiota. Front Immunol. 12:6286292021. View Article : Google Scholar : PubMed/NCBI
|
|
160
|
Li XX, Hara I and Matsumiya T: Effects of
osthole on postmenopausal osteoporosis using ovariectomized rats;
comparison to the effects of estradiol. Biol Pharm Bull.
25:738–742. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
161
|
Xu L, Zhu J, Rong L, Yang H, Wang B, Lu S,
Zhang L, Li F, Yang S, Wang Z, et al: Osteoblast-specific
down-regulation of NLRP3 inflammasome by aptamer-functionalized
liposome nanoparticles improves bone quality in postmenopausal.
Theranostics. 14:3945–3962. 2024. View Article : Google Scholar
|
|
162
|
Cornish J, Callon KE, Bava U, Lin C, Naot
D, Hill BL, Grey AB, Broom N, Myers DE, Nicholson GC and Reid IR:
Leptin directly regulates bone cell function in vitro and reduces
bone fragility in vivo. J Endocrinol. 175:405–415. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
163
|
Rios JL, Bomhof MR, Reimer RA, Hart DA,
Collins KH and Herzog W: Protective effect of prebiotic and
exercise intervention on knee health in a rat model of diet-induced
obesity. Sci Rep. 9:38932019. View Article : Google Scholar : PubMed/NCBI
|
|
164
|
Hong S, Nguyen BN, Min H, Youn HY, Choi S,
Hitayezu E, Cha KH, Park YT, Lee CG, Yoo G, et al: Host-specific
effects of Eubacterium species on Rg3-mediated modulation of
osteosarcopenia in a genetically diverse mouse population.
Microbiome. 12:2512024. View Article : Google Scholar : PubMed/NCBI
|
|
165
|
Meissner M, Lombardo E, Havinga R, Tietge
UJ, Kuipers F and Groen AK: Voluntary wheel running increases bile
acid as well as cholesterol excretion and decreases atherosclerosis
in hypercholesterolemic mice. Atherosclerosis. 218:323–329. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
166
|
Chen See JR, Amos D, Wright J, Lamendella
R and Santanam N: Synergistic effects of exercise and catalase
overexpression on gut microbiome. Environ Microbiol. 24:4220–4235.
2022. View Article : Google Scholar
|
|
167
|
Munukka E, Ahtiainen JP, Puigbó P,
Jalkanen S, Pahkala K, Keskitalo A, Kujala UM, Pietilä S, Hollmén
M, Elo L, et al: Six-week endurance exercise alters gut metagenome
that is not reflected in systemic metabolism in over-weight women.
Front Microbiol. 9:23232018. View Article : Google Scholar : PubMed/NCBI
|
|
168
|
Uday S and Högler W: Nutritional rickets
and osteomalacia in the twenty-first century: Revised concepts,
public health, and prevention strategies. Curr Osteoporos Rep.
15:293–302. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
169
|
Méndez-Sánchez L, Clark P, Winzenberg TM,
Tugwell P, Correa-Burrows P and Costello R: Calcium and vitamin D
for increasing bone mineral density in premenopausal women.
Cochrane Database Syst Rev. 1:CD0126642023.PubMed/NCBI
|
|
170
|
Ilesanmi-Oyelere BL, Roy NC and Kruger MC:
Modulation of bone and joint biomarkers, gut microbiota, and
inflammation status by synbiotic supplementation and weight-bearing
exercise: Human study protocol for a randomized controlled trial.
JMIR Res Protoc. 10:e301312021. View
Article : Google Scholar : PubMed/NCBI
|
|
171
|
Luo B, Xiang D, Nieman DC and Chen P: The
effects of moderate exercise on chronic stress-induced intestinal
barrier dysfunction and antimicrobial defense. Brain Behav Immun.
39:99–106. 2014. View Article : Google Scholar
|
|
172
|
Fu R, Niu R, Zhao F, Wang J, Cao Q, Yu Y,
Liu C, Zhang D and Sun Z: Exercise alleviated intestinal damage and
microbial disturbances in mice exposed to fluoride. Chemosphere.
288:1326582022. View Article : Google Scholar
|
|
173
|
Donohoe DR, Garge N, Zhang X, Sun W,
O'Connell TM, Bunger MK and Bultman SJ: The microbiome and butyrate
regulate energy metabolism and autophagy in the mammalian colon.
Cell Metab. 13:517–526. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
174
|
Huang WC, Tung CL, Yang YSH, Lin IH, Ng XE
and Tung YT: Endurance exercise ameliorates Western diet-induced
atherosclerosis through modulation of microbiota and its
metabolites. Sci Rep. 12:36122022. View Article : Google Scholar : PubMed/NCBI
|
|
175
|
Saito T, Ono R, Kono S, Asano M, Fukuta A,
Tanaka Y, Takao S and Sakai Y: Physical activity among patients
with breast cancer receiving aromatase inhibitors is associated
with bone health: A cross-sectional observational study. Breast
Cancer Res Treat. 182:187–193. 2020. View Article : Google Scholar : PubMed/NCBI
|
