[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons <em>in vitro</em>

Xu,Tan-Zhen; Shen,Xiao-Yan; Sun,Ling-Ling; Chen,Ya-Li; Zhang,Bi-Qiong; Huang,Da-Ke; Li,Wei-Zu

doi:10.3892/ijmm.2026.5988

November-2026 Volume 58 Issue 5

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November-2026 Volume 58 Issue 5

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Authors:
- Tan-Zhen Xu
- Xiao-Yan Shen
- Ling-Ling Sun
- Ya-Li Chen
- Bi-Qiong Zhang
- Da-Ke Huang
- Wei-Zu Li
View Affiliations / Copyright

Affiliations: Department of Pharmacology, Key Laboratory of Anti‑inflammatory and Immunopharmacology, Ministry of Education, Anhui Medical University, Hefei, Anhui 230032, P.R. China, Synthetic Laboratory of Basic Medicine College, Anhui Medical University, Hefei, Anhui 230032, P.R. China

Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 317
|
Published online on: September 16, 2026

https://doi.org/10.3892/ijmm.2026.5988
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Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by an interested reader that an unsuitable antibody may have been used as a part of the western blot analysis shown in Fig. 3A on p. 720. The anti‑β‑galactosidase antibody (cat. no. ab9361; Abcam) that was employed, which is specific for the E. coli β‑galactosidase encoded by the LacZ gene; is only distantly related to the human protein, and would not necessarily be expected to bind to it. The authors have been contacted by the Editorial Office to offer an explanation for the selection of this apparently unsuitable antibody for the western blot analysis, and we are awaiting their response. Owing to the fact that the Editorial Office has been made aware of a potential problem surrounding the design of this experiment in this study, we are issuing an Expression of Concern to notify readers of this issue while the Editorial Office continues to investigate this matter further. [International Journal of Molecular Medicine 43: 717‑726, 2019; DOI: 10.3892/ijmm.2018.4005]

Int J Mol Med 43: [Related article:] 717-726, 2019; DOI: 10.3892/ijmm.2018.4005

The authors have been contacted by the Editorial Office to offer an explanation for the selection of this apparently unsuitable antibody for the western blot analysis, and we are awaiting their response. Owing to the fact that the Editorial Office has been made aware of a potential problem surrounding the design of this experiment in this study, we are issuing an Expression of Concern to notify readers of this issue while the Editorial Office continues to investigate this matter further.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

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Abstract

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