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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Oct 1999 Volume 4 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Oct 1999 Volume 4 Issue 4

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Article

Molecular bases for the anti-HIV-1 effect of NO. Commentary.

  • Authors:
    • T Persichini
    • P Ascenzi
    • V Colizzi
    • M Fraziano
    • G Venturini
    • M Colasanti
  • View Affiliations / Copyright

    Affiliations: Department of Biology, University of Rome <Roma Tre>, I-00146 Rome, Italy.
  • Pages: 365-373
    |
    Published online on: October 1, 1999
       https://doi.org/10.3892/ijmm.4.4.365
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Abstract

In infected human cells, nitric oxide (NO) has been shown to inhibit the replication of the human immunodeficiency virus-1 (HIV-1), the etiological agent of AIDS. Evidence suggests that NO may regulate HIV-1 replication by affecting the sulphydryl redox state. In this respect, it has been very recently demonstrated that NO-donors inactivate the HIV-1-encoded protease and reverse transcriptase in vitro. Further viral and host NO targets may be envisaged. Although no data are available on the anti-HIV-1 effect of NO in vivo, NO-releasing drugs, clinically used in the treatment of cardiovascular disorders, may represent a novel class of molecules for decreasing virus replication. Here, the possible molecular bases for the anti-HIV-1 effect of NO are discussed.

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Copy and paste a formatted citation
Spandidos Publications style
Persichini T, Ascenzi P, Colizzi V, Fraziano M, Venturini G and Colasanti M: Molecular bases for the anti-HIV-1 effect of NO. Commentary.. Int J Mol Med 4: 365-373, 1999.
APA
Persichini, T., Ascenzi, P., Colizzi, V., Fraziano, M., Venturini, G., & Colasanti, M. (1999). Molecular bases for the anti-HIV-1 effect of NO. Commentary.. International Journal of Molecular Medicine, 4, 365-373. https://doi.org/10.3892/ijmm.4.4.365
MLA
Persichini, T., Ascenzi, P., Colizzi, V., Fraziano, M., Venturini, G., Colasanti, M."Molecular bases for the anti-HIV-1 effect of NO. Commentary.". International Journal of Molecular Medicine 4.4 (1999): 365-373.
Chicago
Persichini, T., Ascenzi, P., Colizzi, V., Fraziano, M., Venturini, G., Colasanti, M."Molecular bases for the anti-HIV-1 effect of NO. Commentary.". International Journal of Molecular Medicine 4, no. 4 (1999): 365-373. https://doi.org/10.3892/ijmm.4.4.365
Copy and paste a formatted citation
x
Spandidos Publications style
Persichini T, Ascenzi P, Colizzi V, Fraziano M, Venturini G and Colasanti M: Molecular bases for the anti-HIV-1 effect of NO. Commentary.. Int J Mol Med 4: 365-373, 1999.
APA
Persichini, T., Ascenzi, P., Colizzi, V., Fraziano, M., Venturini, G., & Colasanti, M. (1999). Molecular bases for the anti-HIV-1 effect of NO. Commentary.. International Journal of Molecular Medicine, 4, 365-373. https://doi.org/10.3892/ijmm.4.4.365
MLA
Persichini, T., Ascenzi, P., Colizzi, V., Fraziano, M., Venturini, G., Colasanti, M."Molecular bases for the anti-HIV-1 effect of NO. Commentary.". International Journal of Molecular Medicine 4.4 (1999): 365-373.
Chicago
Persichini, T., Ascenzi, P., Colizzi, V., Fraziano, M., Venturini, G., Colasanti, M."Molecular bases for the anti-HIV-1 effect of NO. Commentary.". International Journal of Molecular Medicine 4, no. 4 (1999): 365-373. https://doi.org/10.3892/ijmm.4.4.365
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