Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.

  • Authors:
    • H Misawa
    • M Yamaguchi
  • View Affiliations

  • Published online on: March 1, 2000     https://doi.org/10.3892/ijmm.5.3.283
  • Pages: 283-290
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Abstract

Regucalcin is a Ca2+-binding protein which plays a regulatory role in liver cell functions related to Ca2+. In this study we have cloned and characterized cDNA for regucalcin from human liver and human hepatoma cell line Hep G2 by screening and rapid amplification of cDNA ends (RACE). The nucleotide sequences of the clones revealed that they were identical in their coding region and differed only in their 5' untranslated regions (UTRs). Northern blot analysis showed that regucalcin mRNA in the Hep G2 was longer than that of the liver. The present study demonstrates the existence of transcript heterogeneity of the human gene for regucalcin.

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Mar 2000
Volume 5 Issue 3

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Misawa H and Yamaguchi M: Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.. Int J Mol Med 5: 283-290, 2000.
APA
Misawa, H., & Yamaguchi, M. (2000). Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.. International Journal of Molecular Medicine, 5, 283-290. https://doi.org/10.3892/ijmm.5.3.283
MLA
Misawa, H., Yamaguchi, M."Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.". International Journal of Molecular Medicine 5.3 (2000): 283-290.
Chicago
Misawa, H., Yamaguchi, M."Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.". International Journal of Molecular Medicine 5, no. 3 (2000): 283-290. https://doi.org/10.3892/ijmm.5.3.283