search button

Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells

  • Authors:
    • Y. Miyahara
    • H. Hibasami
    • H. Katsuzaki
    • K. Imai
    • T. Komiya

  • View Affiliations

  • Published online on: April 1, 2001     https://doi.org/10.3892/ijmm.7.4.369
  • Pages: 369-371
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The exposure of human lymphoid leukemia Molt 4B cells to sesamolin, a component of sesame seed led to both growth inhibition and the induction of apoptosis. Morphological change showing apoptotic bodies was observed in the cells treated with sesamolin. The fragmentation of DNA by sesamolin to oligonucleosomal-sized fragments that are characteristics of apoptosis was observed to be concentration- and time-dependent. These findings suggest that growth inhibition of Molt 4B cells by sesamolin results from the induction of apoptosis in the cells.

Related Articles

Journal Cover

April 2001
Volume 7 Issue 4

Print ISSN: 1107-3756
Online ISSN:1791-244X

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 5.4
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 10.7
  • CiteScore Rank: Q1: #35/328 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 0.994
  • SCImago Journal Rank (SJR): 0.922
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
Miyahara Y, Hibasami H, Katsuzaki H, Imai K and Komiya T: Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells. Int J Mol Med 7: 369-371, 2001
APA
Miyahara, Y., Hibasami, H., Katsuzaki, H., Imai, K., & Komiya, T. (2001). Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells. International Journal of Molecular Medicine, 7, 369-371. https://doi.org/10.3892/ijmm.7.4.369
MLA
Miyahara, Y., Hibasami, H., Katsuzaki, H., Imai, K., Komiya, T."Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells". International Journal of Molecular Medicine 7.4 (2001): 369-371.
Chicago
Miyahara, Y., Hibasami, H., Katsuzaki, H., Imai, K., Komiya, T."Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells". International Journal of Molecular Medicine 7, no. 4 (2001): 369-371. https://doi.org/10.3892/ijmm.7.4.369