Alteration of A549 carcinoma cell protein synthesis profile induced by lung cancer patient serum

  • Authors:
    • Marcos Eduardo Machado Paschoal
    • Maria Da Gloria da Costa Carvalho
  • View Affiliations

  • Published online on: August 1, 2001     https://doi.org/10.3892/ijmm.8.2.211
  • Pages: 211-215
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Several elements such as circulating DNA and metastatic cells, containing the same primary tumor mutations, oncogenic proteins, cytokines, and other tumor related not yet identified factors, can be found in the blood stream of cancer patients. In this study we have shown that serum factors presented in lung cancer patients can modify the protein profile of the lung adenocarcinoma cell line (A549). This alteration in cellular protein profile can be an important event in the cell phenotype modification necessary for the advance of the disease. There have been no similar studies regarding cancer cell protein synthesis induction by human cancer serum.

Related Articles

Journal Cover

August 2001
Volume 8 Issue 2

Print ISSN: 1107-3756
Online ISSN:1791-244X

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Machado Paschoal ME and Machado Paschoal ME: Alteration of A549 carcinoma cell protein synthesis profile induced by lung cancer patient serum. Int J Mol Med 8: 211-215, 2001
APA
Machado Paschoal, M.E., & Machado Paschoal, M.E. (2001). Alteration of A549 carcinoma cell protein synthesis profile induced by lung cancer patient serum. International Journal of Molecular Medicine, 8, 211-215. https://doi.org/10.3892/ijmm.8.2.211
MLA
Machado Paschoal, M. E., Da Gloria da Costa Carvalho, M."Alteration of A549 carcinoma cell protein synthesis profile induced by lung cancer patient serum". International Journal of Molecular Medicine 8.2 (2001): 211-215.
Chicago
Machado Paschoal, M. E., Da Gloria da Costa Carvalho, M."Alteration of A549 carcinoma cell protein synthesis profile induced by lung cancer patient serum". International Journal of Molecular Medicine 8, no. 2 (2001): 211-215. https://doi.org/10.3892/ijmm.8.2.211