Zaltoprofen inhibits concanavalin A-induced decrease of body weight in mice

  • Authors:
    • Toshihiro Okamoto
    • Toru Kawasaki
    • Yoriko Masuda
  • View Affiliations

  • Published online on: September 1, 2001     https://doi.org/10.3892/ijmm.8.3.315
  • Pages: 315-317
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Abstract

Treatment of mice with concanavalin A (Con A) (12.5 mg/kg, i.v.) decreased the body weight at 24 h. This Con A-induced body weight decrease was accompanied by reduction in food and water intake. Zaltoprofen is a non-steroidal anti-inflammatory drug. The administration of Zaltoprofen (10 mg/kg) at 8 h after Con A treatment was found to inhibit the Con A-induced reduction in body weight. The food intake in mice treated with Con A plus Zaltoprofen (10 mg/kg) was four times greater than that in mice treated with only Con A. The present results showed inhibition of the Con A-induced body weight loss by Zaltoprofen and suggested its possible effectiveness for the treatment of .

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September 2001
Volume 8 Issue 3

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Copy and paste a formatted citation
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Spandidos Publications style
Okamoto T, Kawasaki T and Masuda Y: Zaltoprofen inhibits concanavalin A-induced decrease of body weight in mice. Int J Mol Med 8: 315-317, 2001
APA
Okamoto, T., Kawasaki, T., & Masuda, Y. (2001). Zaltoprofen inhibits concanavalin A-induced decrease of body weight in mice. International Journal of Molecular Medicine, 8, 315-317. https://doi.org/10.3892/ijmm.8.3.315
MLA
Okamoto, T., Kawasaki, T., Masuda, Y."Zaltoprofen inhibits concanavalin A-induced decrease of body weight in mice". International Journal of Molecular Medicine 8.3 (2001): 315-317.
Chicago
Okamoto, T., Kawasaki, T., Masuda, Y."Zaltoprofen inhibits concanavalin A-induced decrease of body weight in mice". International Journal of Molecular Medicine 8, no. 3 (2001): 315-317. https://doi.org/10.3892/ijmm.8.3.315