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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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August 2009 Volume 24 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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August 2009 Volume 24 Issue 2

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Article

The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids

  • Authors:
    • Laurence Portois
    • Mirjam Hacquebard
    • Willy J. Malaisse
    • Yvon A. carpentier
  • View Affiliations / Copyright

    Affiliations: Laboratory of Experimental Surgery, Université Libre de Bruxelles, B-1070 Brussels, Belgium
  • Pages: 269-278
    |
    Published online on: August 1, 2009
       https://doi.org/10.3892/ijmm_00000230
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Abstract

Rats exposed from 7 weeks after birth and for the ensuing 3 to 7 months to a diet depleted in long-chain polyunsaturated ω3 fatty acids were recently proposed as a new animal model for the metabolic syndrome. The present study aimed mainly at investigating whether, in this new model, the perturbation of the fatty acid total content and pattern of brain phospholipids simulates that previously documented in second-generation ω3-depleted rats. Such was indeed the case, with the apparent exception of changes in the C18:1ω9, C20:0, C22:0 and C24:0 relative content of brain phospholipids. Moreover, the C22:5ω3 content of such phospholipids was unexpectedly lower in the present model than in the second-generation ω3-depleted rats. The changes in brain phospholipids were also monitored when the rats deprived of ω3 fatty acids for 7 months were given access for 2 to 4-5 weeks to a flaxseed oil-enriched diet. Most phospholipid variables were rapidly normalized under the latter experimental conditions. The results obtained under these conditions suggest that an increase in the brain phospholipid C22:5ω3 content may play a key role in the orexigenic effects of exogenous ω3 fatty acids supplied to ω3-depleted animals.

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Copy and paste a formatted citation
Spandidos Publications style
Portois L, Hacquebard M, Malaisse WJ and carpentier YA: The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids. Int J Mol Med 24: 269-278, 2009.
APA
Portois, L., Hacquebard, M., Malaisse, W.J., & carpentier, Y.A. (2009). The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids. International Journal of Molecular Medicine, 24, 269-278. https://doi.org/10.3892/ijmm_00000230
MLA
Portois, L., Hacquebard, M., Malaisse, W. J., carpentier, Y. A."The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids". International Journal of Molecular Medicine 24.2 (2009): 269-278.
Chicago
Portois, L., Hacquebard, M., Malaisse, W. J., carpentier, Y. A."The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids". International Journal of Molecular Medicine 24, no. 2 (2009): 269-278. https://doi.org/10.3892/ijmm_00000230
Copy and paste a formatted citation
x
Spandidos Publications style
Portois L, Hacquebard M, Malaisse WJ and carpentier YA: The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids. Int J Mol Med 24: 269-278, 2009.
APA
Portois, L., Hacquebard, M., Malaisse, W.J., & carpentier, Y.A. (2009). The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids. International Journal of Molecular Medicine, 24, 269-278. https://doi.org/10.3892/ijmm_00000230
MLA
Portois, L., Hacquebard, M., Malaisse, W. J., carpentier, Y. A."The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids". International Journal of Molecular Medicine 24.2 (2009): 269-278.
Chicago
Portois, L., Hacquebard, M., Malaisse, W. J., carpentier, Y. A."The metabolic syndrome of ω3-depleted rats. III. Brain phospholipids". International Journal of Molecular Medicine 24, no. 2 (2009): 269-278. https://doi.org/10.3892/ijmm_00000230
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