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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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September 2009 Volume 24 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 2009 Volume 24 Issue 3

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Review

Keloids: Current concepts of pathogenesis (Review)

  • Authors:
    • Gregor M. Bran
    • Ulrich R. Goessler
    • Karl Hormann
    • Frank Riedel
    • Haneen Sadick

  • View Affiliations / Copyright

    Affiliations: Department of Otolaryngology, Head and Neck Surgery, University Hospital of Mannheim, D-68167 Mannheim, Germany. gregor.bran@hno.ma.uni-heidelberg.de
  • Pages: 283-293
    |
    Published online on: September 1, 2009
       https://doi.org/10.3892/ijmm_00000231
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Abstract

Excess scar formation occurs after dermal injury as a result of abnormal wound healing. Hypertrophic scars and keloids both represent fibrotic skin conditions which can be very difficult, even frustrating, to treat. Identification of differences between hypertrophic scars, keloids and normal scars are a prerequisite for finding the correct therapeutical concept. Despite the relatively high prevalence of keloids in the general population, the mechanisms underlying keloid formation are only partially understood. This fact is reflected in the multiple treatment modalities, of which no single treatment has proven to be widely effective. Advances in our understanding of the wound healing process reveal new pathophysiological concepts for keloid formation. Our article presents an overview on physiological wound healing and the pathogenesis of scar formation, differentiates keloids from hypertrophic scars and reviews current hypotheses for keloid formation. This information might assist in deciphering the complexity of keloid pathogenesis and help in the development of an efficacious therapeutical strategy.

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Copy and paste a formatted citation
Spandidos Publications style
Bran GM, Goessler UR, Hormann K, Riedel F and Sadick H: Keloids: Current concepts of pathogenesis (Review). Int J Mol Med 24: 283-293, 2009.
APA
Bran, G.M., Goessler, U.R., Hormann, K., Riedel, F., & Sadick, H. (2009). Keloids: Current concepts of pathogenesis (Review). International Journal of Molecular Medicine, 24, 283-293. https://doi.org/10.3892/ijmm_00000231
MLA
Bran, G. M., Goessler, U. R., Hormann, K., Riedel, F., Sadick, H."Keloids: Current concepts of pathogenesis (Review)". International Journal of Molecular Medicine 24.3 (2009): 283-293.
Chicago
Bran, G. M., Goessler, U. R., Hormann, K., Riedel, F., Sadick, H."Keloids: Current concepts of pathogenesis (Review)". International Journal of Molecular Medicine 24, no. 3 (2009): 283-293. https://doi.org/10.3892/ijmm_00000231
Copy and paste a formatted citation
x
Spandidos Publications style
Bran GM, Goessler UR, Hormann K, Riedel F and Sadick H: Keloids: Current concepts of pathogenesis (Review). Int J Mol Med 24: 283-293, 2009.
APA
Bran, G.M., Goessler, U.R., Hormann, K., Riedel, F., & Sadick, H. (2009). Keloids: Current concepts of pathogenesis (Review). International Journal of Molecular Medicine, 24, 283-293. https://doi.org/10.3892/ijmm_00000231
MLA
Bran, G. M., Goessler, U. R., Hormann, K., Riedel, F., Sadick, H."Keloids: Current concepts of pathogenesis (Review)". International Journal of Molecular Medicine 24.3 (2009): 283-293.
Chicago
Bran, G. M., Goessler, U. R., Hormann, K., Riedel, F., Sadick, H."Keloids: Current concepts of pathogenesis (Review)". International Journal of Molecular Medicine 24, no. 3 (2009): 283-293. https://doi.org/10.3892/ijmm_00000231
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