The role of ghrelin in energy homeostasis and its potential clinical relevance (Review)

  • Authors:
    • Kai-Chun Cheng
    • Ying-Xiao Li
    • Akihiro Asakawa
    • Akio Inui
  • View Affiliations

  • Published online on: December 1, 2010     https://doi.org/10.3892/ijmm_00000524
  • Pages: 771-778
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Abstract

The novel gastric hormone ghrelin, a 28-amino acid peptide, has been identified as a potent growth-hormone secretagogue. Ghrelin production is regulated by nutritional and hormonal factors. Besides stimulating growth hormone secretion, studies show that ghrelin exerts a number of central and peripheral actions such as the regulation of food intake, the control of energy balance, glucose metabolism and insulin release, cardiovascular actions, the stimulation of gastric acid secretion, and motility. The broad spectrum of biological activities associated with ghrelin continues to expand. In the future, the diverse functions of ghrelin raise the possibility of its clinical application in a large number of pathological conditions.

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December 2010
Volume 26 Issue 6

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Cheng K, Li Y, Asakawa A and Inui A: The role of ghrelin in energy homeostasis and its potential clinical relevance (Review) . Int J Mol Med 26: 771-778, 2010.
APA
Cheng, K., Li, Y., Asakawa, A., & Inui, A. (2010). The role of ghrelin in energy homeostasis and its potential clinical relevance (Review) . International Journal of Molecular Medicine, 26, 771-778. https://doi.org/10.3892/ijmm_00000524
MLA
Cheng, K., Li, Y., Asakawa, A., Inui, A."The role of ghrelin in energy homeostasis and its potential clinical relevance (Review) ". International Journal of Molecular Medicine 26.6 (2010): 771-778.
Chicago
Cheng, K., Li, Y., Asakawa, A., Inui, A."The role of ghrelin in energy homeostasis and its potential clinical relevance (Review) ". International Journal of Molecular Medicine 26, no. 6 (2010): 771-778. https://doi.org/10.3892/ijmm_00000524