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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2010 Volume 26 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

The role of ghrelin in energy homeostasis and its potential clinical relevance (Review)

Kai-Chun Cheng, Ying-Xiao Li, Akihiro Asakawa, Akio Inui
Pages: 771-778
Published online on: 01 December 2010

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Article

The mechanism of atopic march may be the ‘social’ event of cells and molecules (Review)

Junming Luo, Yingxin Li, Rujun Gong
Pages: 779-785
Published online on: 01 December 2010

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Article Open Access

Cholesterol-dependent induction of dendrite formation by ginsenoside Rh2 in cultured melanoma cells

Yong-Sheng Jiang, Zhe-Xiong Jin, Hisanori Umehara, Takahide Ota
Pages: 787-793
Published online on: 01 December 2010

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Article Open Access

N-acetyl-seryl-aspartyl-lysyl-proline attenuates renal inflammation and tubulointerstitial fibrosis in rats

Mingao Wang, Ruichan Liu, Xibei Jia, Suhong Mu, Rujuan Xie
Pages: 795-801
Published online on: 01 December 2010

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Article

Monoclonal antibody to the six-transmembrane epithelial antigen of prostate 4 promotes apoptosis and inhibits proliferation and glucose uptake in human adipocytes

Da-Ni Qin, Chun-Zhao Kou, Yu-Hui Ni, Chun-Mei Zhang, Jin-Gai Zhu, Chun Zhu, Yan-Ping Wang, Guan-Zhong Zhu, Chunmei Shi, Chen-Bo Ji, Xi-Rong Guo
Pages: 803-811
Published online on: 01 December 2010

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Article

RAGE ligands induce apoptotic cell death of pancreatic β-cells via oxidative stress

Byung-Wan Lee, Hee Young Chae, Soo Jin Kwon, So Youn Park, Jahei Ihm, Sung-Hee Ihm
Pages: 813-818
Published online on: 01 December 2010

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Article

MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein

Yanhui Lou, Xingsheng Yang, Fuling Wang, Zhumei Cui, Yu Huang
Pages: 819-827
Published online on: 01 December 2010

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Article

Proteomic analysis of oxidative stress-induced neuronal cell death by using two-dimensional fluorescence difference gel electrophoresis

Eun Young Kim, Tae-Sung Yoon, Young Jae Bahn, Dae Gwin Jeong, Mi Rim Park, Sang J. Chung, Sung Goo Park, Byoung Chul Park, Sang Chul Lee, Seong Eon Ryu, Kwang-Hee Bae
Pages: 829-835
Published online on: 01 December 2010

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Article

Comparison of MammaPrint and TargetPrint results with clinical parameters in German patients with early stage breast cancer

Heidrun Gevensleben, Uwe-Jochen Göhring, Reinhard Büttner, Lukas C. Heukamp, Georg Kunz, Thomas Dimpfl, Christian Jackisch, Olaf Ortmann, Ute-Susann Albert, Richard Bender, Femke De Snoo, Oscar Krijgsman, Annuska M. Glas, Yavuz H. Ergönenc, Corinna Vogel, August Dykgers, Claus Langwieder, Martin Rees, Tobias Anzeneder
Pages: 837-843
Published online on: 01 December 2010

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Article

Enhanced enteric invasion of scrapie agents into the villous columnar epithelium via maternal immunoglobulin

Yasuhisa Ano, Akikazu Sakudo, Ryuta Uraki, Yukita Sato, Jyuri Kono, Katsuaki Sugiura, Takashi Yokoyama, Shigeyoshi Itohara, Hiroyuki Nakayama, Masayoshi Yukawa, Takashi Onodera
Pages: 845-851
Published online on: 01 December 2010

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Article

Internalization of REIC/Dkk-3 protein by induced pluripotent stem cell-derived embryoid bodies and extra-embryonic tissues

Ken Kataoka, Masakiyo Sakaguchi, Kun Peng Li, Chika Taketa, Ken-Ichi Yamamoto, Gang Du, Hiroaki Funahashi, Hitoshi Murata, Nam-Ho Huh
Pages: 853-859
Published online on: 01 December 2010

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Article

p63 (TP73L) a key player in embryonic urogential development with significant dysregulation in human bladder exstrophy tissue

Bonnie J. Ching, Lars Wittler, Judith Proske, Garima Yagnik, Lihong Qi, Markus Draaken, Heiko Reutter, John P. Gearhart, Michael Ludwig, Simeon A. Boyadjiev
Pages: 861-867
Published online on: 01 December 2010

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Article

T lymphocyte responses against hepatitis B virus-related hepatocellular carcinoma induced by adenovirus vaccine encoding HBx

Yuhua Li, Ping Cheng, Yanjun Wen, Ping Chen, Li Yang, Xia Zhao, Huimin Lv, Qingli Quan, Yonglin Wu, Huiqiang Yang, Jie Liu, Xueru Wen, Nina Liu, Zhuang Kang, Shan Luo, Lian Wang, Yuquan Wei
Pages: 869-876
Published online on: 01 December 2010

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Article

Effect of omeprazole on the expression of transcription factors in osteoclasts and osteoblasts

Jong Jin Hyun, Hoon Jai Chun, Bora Keum, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hong Sik Lee, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu, Sin Gon Kim, Woon-Won Jung
Pages: 877-883
Published online on: 01 December 2010

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Article

COMP and Col9A3 mutations and their relationship to the pseudoachondroplasia phenotype

Woon-Won Jung, Gracia Cielo Balce, Jae-Woo Cho, Sung-Chul Jung, Suk-Joo Hong, Hae-Ryong Song
Pages: 885-891
Published online on: 01 December 2010

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Article

The PTEN tumor suppressor inhibits human airway smooth muscle cell migration

Haibing Lan, Haohai Zhong, Yang Gao, Dunqiang Ren, Lili Chen, Dacheng Zhang, Wenyan Lai, Jian Xu, Yaling Luo
Pages: 893-899
Published online on: 01 December 2010

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Article

TGF-β1-treated ADSCs-CM promotes expression of type I collagen and MMP-1, migration of human skin fibroblasts, and wound healing in vitro and in vivo

Jae-We Cho, Min-Chul Kang, Kyu-Suk Lee
Pages: 901-906
Published online on: 01 December 2010

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Article

The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma

Kan Gong, Ning Zhang, Kai Zhang, Yanqun Na
Pages: 907-912
Published online on: 01 December 2010

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Article

Human RCAN3 gene expression and cell growth in endothelial cells

Silvia Canaider, Marina Vettraino, Lucy V. Norling, Enzo Spisni, Federica Facchin, Dianne Cooper, Mauro Perretti
Pages: 913-918
Published online on: 01 December 2010

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Article

Investigation of angiogenetic axis Angiopoietin-1 and -2/Tie-2 in fibrotic lung diseases: A bronchoalveolar lavage study

Giorgos A. Margaritopoulos, Katerina M. Antoniou, Kostas Karagiannis, Evi Vassalou, Ismini Lasithiotaki, Irini Lambiri, Nikos M. Siafakas
Pages: 919-923
Published online on: 01 December 2010

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Article

Evaluation of the effect of α-defensin human neutrophil peptides on neutrophil apoptosis

Isao Nagaoka, Kaori Suzuki, Taisuke Murakami, François Niyonsaba, Hiroshi Tamura, Michimasa Hirata
Pages: 925-934
Published online on: 01 December 2010

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Article

Chamomile: An anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity

Natarajan Bhaskaran, Sanjeev Shukla, Janmejai K. Srivastava, Sanjay Gupta
Pages: 935-940
Published online on: 01 December 2010

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Article

Comparative metabolic profiling of paediatric ependymoma, medulloblastoma and pilocytic astrocytoma

S. Cuellar-Baena, J. M. Morales, H. Martinetto, J. Calvar, G. Sevlever, G. Castellano, M. Cerdá-Nicolás, B. Celda, D. Monleon
Pages: 941-948
Published online on: 01 December 2010

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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