METHODOLOGICAL ASPECTS OF PHASE-I STUDIES OF NOVEL ANTICANCER AGENTS (REVIEW)

  • Authors:
    • J CASSIDY
    • D BISSETT
    • D KERR
  • View Affiliations

  • Published online on: July 1, 1992     https://doi.org/10.3892/ijo.1.2.195
  • Pages: 195-199
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Abstract

In the last 5 years we have performed 14 phase I studies in our department. Eight of these trials involved evaluation of both the clinical and the pharmacokinetic behaviour of novel anti-cancer agents. The remainder investigated various aspects of drug delivery, targetting or resistance modification with existing anti-cancer drugs. In total these studies have involved over 200 patients. In this review article we have drawn upon our experience to suggest guidelines for future studies.

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July 1992
Volume 1 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
CASSIDY J, BISSETT D and KERR D: METHODOLOGICAL ASPECTS OF PHASE-I STUDIES OF NOVEL ANTICANCER AGENTS (REVIEW). Int J Oncol 1: 195-199, 1992
APA
CASSIDY, J., BISSETT, D., & KERR, D. (1992). METHODOLOGICAL ASPECTS OF PHASE-I STUDIES OF NOVEL ANTICANCER AGENTS (REVIEW). International Journal of Oncology, 1, 195-199. https://doi.org/10.3892/ijo.1.2.195
MLA
CASSIDY, J., BISSETT, D., KERR, D."METHODOLOGICAL ASPECTS OF PHASE-I STUDIES OF NOVEL ANTICANCER AGENTS (REVIEW)". International Journal of Oncology 1.2 (1992): 195-199.
Chicago
CASSIDY, J., BISSETT, D., KERR, D."METHODOLOGICAL ASPECTS OF PHASE-I STUDIES OF NOVEL ANTICANCER AGENTS (REVIEW)". International Journal of Oncology 1, no. 2 (1992): 195-199. https://doi.org/10.3892/ijo.1.2.195