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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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August 1992 Volume 1 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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August 1992 Volume 1 Issue 3

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Article

MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS

  • Authors:
    • PK LIPPONEN

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    Affiliations: Affliations not specified
  • Pages: 387-392
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    Published online on: August 1, 1992
       https://doi.org/10.3892/ijo.1.3.387
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Abstract

This review summarises recent prognostic results by mitotic indices in human tumours. The prognostic value of the mitotic indices is evaluated in breast carcinoma, in transitional cell bladder carcinoma, in ovarian carcinoma, in pancreatic carcinoma and in prostatic adenocarcinoma. The results show that mitotic indices can efficiently categorise particularly breast carcinomas, transitional cell bladder carcinomas and ovarian carcinomas into groups of distinctly different prognoses. The mitotic frequency 10 mitotic figures per mm2 of neoplastic tissue seems critical. The survival of patients with slowly proliferating tumours is significantly better than the survival of patients with a mitotic frequency over 10 mitotic fiqures per mm2 of neoplastic tissue. Methodological analyses also indicate that mitotic indices are reproducible and accordingly suitable for grading of tumours in clinical context. However, there are several variation factors related to mitosis counts like variation related to a delay in fixation, intratumoural variations, and variations related to observational reasons. Adequate standardization of fixation and measurement process probably improve the prognostic estimates based on mitosis counts.

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Copy and paste a formatted citation
Spandidos Publications style
LIPPONEN P: MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS. Int J Oncol 1: 387-392, 1992.
APA
LIPPONEN, P. (1992). MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS. International Journal of Oncology, 1, 387-392. https://doi.org/10.3892/ijo.1.3.387
MLA
LIPPONEN, P."MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS". International Journal of Oncology 1.3 (1992): 387-392.
Chicago
LIPPONEN, P."MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS". International Journal of Oncology 1, no. 3 (1992): 387-392. https://doi.org/10.3892/ijo.1.3.387
Copy and paste a formatted citation
x
Spandidos Publications style
LIPPONEN P: MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS. Int J Oncol 1: 387-392, 1992.
APA
LIPPONEN, P. (1992). MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS. International Journal of Oncology, 1, 387-392. https://doi.org/10.3892/ijo.1.3.387
MLA
LIPPONEN, P."MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS". International Journal of Oncology 1.3 (1992): 387-392.
Chicago
LIPPONEN, P."MITOTIC INDEXES AS INDICATORS OF MALIGNANCY IN HUMAN TUMORS". International Journal of Oncology 1, no. 3 (1992): 387-392. https://doi.org/10.3892/ijo.1.3.387
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