Expression of variant forms of fibroblast growth factor receptor 2 mRNA in human breast carcinomas

  • Authors:
    • F PenaultLlorca
    • P Parc
    • F Coulier
    • F Bertucci
    • J Jacquemier
    • D Birnbaum
  • View Affiliations

  • Published online on: June 1, 1997     https://doi.org/10.3892/ijo.10.6.1191
  • Pages: 1191-1196
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Abstract

FGF (fibroblast growth factors) and FGF receptors may play a role in stroma-epithelium relationships in the mammary gland. Dysregulation of their interactions may be important in mammary carcinogenesis. Isoforms of the FGFR2 receptor, differing in the structure of the extracellular region, are expressed in the mammary gland and may diversely affect stroma-epithelium relationships. We determined the mRNA variants encoding these isoforms in human cell lines and breast carcinomas. All possible combinations of variants were found. No correlation was observed between the presence of a particular variant and the expression of any FGF gene tested, or the status of any histoclinical parameter.

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June 1997
Volume 10 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
PenaultLlorca F, Parc P, Coulier F, Bertucci F, Jacquemier J and Birnbaum D: Expression of variant forms of fibroblast growth factor receptor 2 mRNA in human breast carcinomas. Int J Oncol 10: 1191-1196, 1997
APA
PenaultLlorca, F., Parc, P., Coulier, F., Bertucci, F., Jacquemier, J., & Birnbaum, D. (1997). Expression of variant forms of fibroblast growth factor receptor 2 mRNA in human breast carcinomas. International Journal of Oncology, 10, 1191-1196. https://doi.org/10.3892/ijo.10.6.1191
MLA
PenaultLlorca, F., Parc, P., Coulier, F., Bertucci, F., Jacquemier, J., Birnbaum, D."Expression of variant forms of fibroblast growth factor receptor 2 mRNA in human breast carcinomas". International Journal of Oncology 10.6 (1997): 1191-1196.
Chicago
PenaultLlorca, F., Parc, P., Coulier, F., Bertucci, F., Jacquemier, J., Birnbaum, D."Expression of variant forms of fibroblast growth factor receptor 2 mRNA in human breast carcinomas". International Journal of Oncology 10, no. 6 (1997): 1191-1196. https://doi.org/10.3892/ijo.10.6.1191