Clinical significance of integrin alpha 6 mRNA expression in gastric carcinoma

  • Authors:
    • K Mimori
    • M Mori
    • N Begum
    • S Tanaka
    • M Haraguchi
    • H Ueo
    • N Karimine
    • T Akiyoshi
    • G Barnard
  • View Affiliations

  • Published online on: November 1, 1997     https://doi.org/10.3892/ijo.11.5.959
  • Pages: 959-964
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Abstract

Integrin alpha 6 is believed to be involved in malignant biological development. High tumor/normal (T/N) ratio of integrin alpha 6 was observed in intestinal type tumors in gastric carcinoma. In an immunohistochemical study, an intense and continuous staining was seen at the basement layer in the intestinal type tumors. Concerning the variant, there was a significant correlation between the expression ratio of variant B/variant A and the depth of tumor invasion. In conclusion, i) integrin alpha 6 expression was intimately correlated with histologic differentiation, and ii) the overexpression of variant B may be correlated with tumor invasion of gastric carcinoma.

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November 1997
Volume 11 Issue 5

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Mimori K, Mori M, Begum N, Tanaka S, Haraguchi M, Ueo H, Karimine N, Akiyoshi T and Barnard G: Clinical significance of integrin alpha 6 mRNA expression in gastric carcinoma. Int J Oncol 11: 959-964, 1997
APA
Mimori, K., Mori, M., Begum, N., Tanaka, S., Haraguchi, M., Ueo, H. ... Barnard, G. (1997). Clinical significance of integrin alpha 6 mRNA expression in gastric carcinoma. International Journal of Oncology, 11, 959-964. https://doi.org/10.3892/ijo.11.5.959
MLA
Mimori, K., Mori, M., Begum, N., Tanaka, S., Haraguchi, M., Ueo, H., Karimine, N., Akiyoshi, T., Barnard, G."Clinical significance of integrin alpha 6 mRNA expression in gastric carcinoma". International Journal of Oncology 11.5 (1997): 959-964.
Chicago
Mimori, K., Mori, M., Begum, N., Tanaka, S., Haraguchi, M., Ueo, H., Karimine, N., Akiyoshi, T., Barnard, G."Clinical significance of integrin alpha 6 mRNA expression in gastric carcinoma". International Journal of Oncology 11, no. 5 (1997): 959-964. https://doi.org/10.3892/ijo.11.5.959