Six novel mutations in the NF2 tumor suppressor gene.

  • Authors:
    • P E Leone
    • M J Bello
    • M Mendiola
    • J Vaquero
    • J L Sarasa
    • M E Kusak
    • J M De Campos
    • A Pestana
    • J A Rey
  • View Affiliations

  • Published online on: April 1, 1998     https://doi.org/10.3892/ijo.12.4.935
  • Pages: 935-943
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Abstract

Six novel mutations were identified in the NF2 tumor suppressor gene in a panel of meningiomas and neurinomas. Screening was performed using a combination of single-strand conformation polymorphism and heteroduplex analyses on polymerase chain reaction-amplified DNA from tumors and matched peripheral blood lymphocytes. Mutations involved exons 2, 7, 11 and 12, and corresponded to three frameshift, one nonsense, one missense and one polymorphism.

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Apr 1998
Volume 12 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Leone P, Bello M, Mendiola M, Vaquero J, Sarasa J, Kusak M, De Campos J, Pestana A and Rey J: Six novel mutations in the NF2 tumor suppressor gene.. Int J Oncol 12: 935-943, 1998
APA
Leone, P., Bello, M., Mendiola, M., Vaquero, J., Sarasa, J., Kusak, M. ... Rey, J. (1998). Six novel mutations in the NF2 tumor suppressor gene.. International Journal of Oncology, 12, 935-943. https://doi.org/10.3892/ijo.12.4.935
MLA
Leone, P., Bello, M., Mendiola, M., Vaquero, J., Sarasa, J., Kusak, M., De Campos, J., Pestana, A., Rey, J."Six novel mutations in the NF2 tumor suppressor gene.". International Journal of Oncology 12.4 (1998): 935-943.
Chicago
Leone, P., Bello, M., Mendiola, M., Vaquero, J., Sarasa, J., Kusak, M., De Campos, J., Pestana, A., Rey, J."Six novel mutations in the NF2 tumor suppressor gene.". International Journal of Oncology 12, no. 4 (1998): 935-943. https://doi.org/10.3892/ijo.12.4.935